Results 51 to 60 of about 43,976 (255)

β-lactam-induced OMV release promotes polymyxin tolerance in Salmonella enterica sv. Typhi

Frontiers in Microbiology
The rise of multidrug-resistant bacteria is a global concern, leading to a renewed reliance on older antibiotics like polymyxins as a last resort. Polymyxins, cationic cyclic peptides synthesized nonribosomally, feature a hydrophobic acyl tail and ...
Pedro Marchant, Erika Vivanco, Andrés Silva, Jan Nevermann, Ignacio Fuentes, Boris Barrera, Carolina Otero, Iván L. Calderón, Fernando Gil, Juan A. Fuentes   +9 more
doaj   +1 more source

Mechanistic Insights From Global Metabolomics Studies into Synergistic Bactericidal Effect of a Polymyxin B Combination With Tamoxifen Against Cystic Fibrosis MDR Pseudomonas aeruginosa

Computational and Structural Biotechnology Journal, 2018
Polymyxins are amongst the most important antibiotics in modern medicine, in recent times their clinical utility has been overshadowed by nosocomial outbreaks of polymyxin resistant MDR Gram-negative ‘superbugs’.
Maytham Hussein, Mei-Ling Han, Yan Zhu, Elena K. Schneider-Futschik, Xiaohan Hu, Qi Tony Zhou, Yu-Wei Lin, Dovile Anderson, Darren J. Creek, Daniel Hoyer, Jian Li, Tony Velkov   +11 more
doaj   +1 more source

Appropriate use of colistin in neonates, infants and children: Interim guidance

Southern African Journal of Infectious Diseases, 2023
No abstract available.
Vindana Chibabhai, Adrie Bekker, Marianne Black, Despina Demopoulos, Angela Dramowski, Nicolette M. du Plessis, Veshni Pillay-Fuentes Lorente, Trusha Nana, Helena Rabie, Gary Reubenson, Reenu Thomas   +10 more
doaj   +1 more source

Evaluation of susceptibility testing methods for polymyxin

, 2010
SummaryBackgroundThe widespread resistance in Gram-negative bacteria has necessitated evaluation of the use of older antimicrobials such as polymyxins. In the present study we evaluated the different susceptibility testing methods for polymyxins B and E ...
Das, Anupam, Farooque, Kamran, Sharma, Vijay, Misra, M.C., Bhoi, Sanjeev, Mathur, Purva, Behera, Bijayini, Gupta, Babita, Kapil, Arti   +8 more
core   +1 more source

Early use of polymyxin B reduces the mortality of carbapenem-resistant Klebsiella pneumoniae bloodstream infection

Brazilian Journal of Infectious Diseases, 2019
Polymyxin B is one of the last resort option for carbapenem-resistant Klebsiella pneumoniae (CRKP) bloodstream infection in China. Therefore, the timing of administration of polymyxin is frequently delayed.
Qiqiang Liang, Man Huang, Zhijiang Xu
doaj   +1 more source

Exploring the Roles of Tuna‐Associated Acinetobacter sp. YFT067: Implications for Host Health and Metabolism

Animal Research and One Health, EarlyView.
This study firstly isolated a tuna‐derived gut probiotic Acinetobacter seifertii YFT067. Dietary administration of YFT067 played significant roles in promoting growth performance, SCFAs production, lipid absorption, and metabolism of the host, indicating YFT067 as a promising probiotic candidate for enhancing tuna aquaculture productivity through ...
Ying Zou, Hai Huang, Qiongyao Fu, Zhiyuan Lu, Zhiqiang Guo   +4 more
wiley   +1 more source

Co‐Infection of Brucella canis and Brucella melitensis in a Domestic Dog With Zoonotic Transmission to Human, China

Animal Research and One Health, EarlyView.
Source attribution figure for human and dogs Brucella canis infections. ABSTRACT We report a rare occurrence of genetic material from both Brucella canis and B. melitensis detected in a domesticated dog from Jiangsu Province, China. The detection was confirmed through serological assays, quantitative PCR (qPCR), metagenomic and genomic sequencing ...
Shengxin Ge, Jian Xu, Qingchun Shen, Jiabo Ding, Xiaowen Yang   +4 more
wiley   +1 more source

Sphingolipid-mediated vesiculation in multidrug-resistant Sphingobacterium detergens under polymyxin B stress

Applied and Environmental Microbiology
Among environmentally widespread Sphingobacterium species, the animal feces isolate Sphingobacterium detergens E70 exhibited multidrug antibiotic resistance despite carrying few annotated antibiotic resistance genes (ARGs), prompting investigation of non-
Jihyeon Min, Yewon Woo, Yerim Park, Woojun Park   +3 more
doaj   +1 more source

Ceftazidime/avibactam Improves the Antibacterial Efficacy of Polymyxin B Against Polymyxin B Heteroresistant KPC-2-Producing Klebsiella pneumoniae and Hinders Emergence of Resistant Subpopulation in vitro

Frontiers in Microbiology, 2019
Due to the increasing multidrug resistance and limited antibiotics, polymyxin B revived as the last resort for the treatment of carbapenemase-producing Klebsiella pneumoniae (CRKP).
Xingyan Ma, Yuting He, Xuegao Yu, Yimei Cai, Jianming Zeng, Jianming Zeng, Renxin Cai, Renxin Cai, Yang Lu, Yang Lu, Liang Chen, Cha Chen, Cha Chen, Bin Huang   +13 more
doaj   +1 more source

Polymyxin-induced neuromuscular weakness: a case report [PDF]

Polymyxin-induced neuromuscular blockade is a rare but potentially fatal condition, with majority of cases that were reported between 1962 and 1973. We describe a patient who developed hypercapnic respiratory failure after initiation of polymyxin for ...
Yihui Goh, Rahul Rathakrishnan, Yee Cheun Chan, Amanda X. Y. Chin, Kay W. P. Ng   +4 more
core   +1 more source