Results 61 to 70 of about 2,001 (190)

Binding of $TMPyP^{3+}$ porphyrin to poly(A)-poly(U) polynucleotide: a spectroscopic study [PDF]

open access: yesarXiv
The porphyrins are macrocyclic compounds widely used as photosensitizers in anticancer photodynamic therapy. The binding of a tricationic meso-tris(N-methylpyridinium)-porphyrin, $TMPyP^{3+}$, to poly(A)-poly(U) polynucleotide has been studied in neutral buffered solution, pH6.9, of low and near-physiological ionic strength in a wide range of molar ...
arxiv  

Optimal experimental design in an EGFR signaling and down-regulation model [PDF]

open access: yesarXiv, 2006
We apply the methods of optimal experimental design to a differential equation model for epidermal growth factor receptor (EGFR) signaling, trafficking, and down-regulation. The model incorporates the role of a recently discovered protein complex made up of the E3 ubiquitin ligase, Cbl, the guanine exchange factor (GEF), Cool-1 (Beta-Pix), and the Rho ...
arxiv  

Splicing Systems from Past to Future: Old and New Challenges [PDF]

open access: yesarXiv, 2015
A splicing system is a formal model of a recombinant behaviour of sets of double stranded DNA molecules when acted on by restriction enzymes and ligase. In this survey we will concentrate on a specific behaviour of a type of splicing systems, introduced by P\u{a}un and subsequently developed by many researchers in both linear and circular case of ...
arxiv  

Two distinct polynucleotide ligases from rat liver [PDF]

open access: yesFEBS Letters, 1975
Kinji Tsukada   +2 more
openaire   +3 more sources

Deciding Whether a Regular Language is Generated by a Splicing System [PDF]

open access: yesarXiv, 2011
Splicing as a binary word/language operation is inspired by the DNA recombination under the action of restriction enzymes and ligases, and was first introduced by Tom Head in 1987. Shortly thereafter, it was proven that the languages generated by (finite) splicing systems form a proper subclass of the class of regular languages.
arxiv  

Polynucleotide Ligase Activity in Adenovirus-Infected Human Embryonic Kidney Cell Cultures

open access: yesExperimental Biology and Medicine, 1970
SummaryCell-free extracts prepared from human embryonic kidney (HEK) cultures after infection with adenovirus 2 or 12 had a decreased ability to repair single-strand breaks in the HEK cell DNA substrate. The apparent loss of polynucleotide ligase activity found in infected cells may be related to the adenovirus-induced inhibition of HEK cell DNA ...
openaire   +3 more sources

Horizontal acquisition of a DNA ligase improves DNA damage tolerance in eukaryotes. [PDF]

open access: yesNat Commun, 2023
Nicolas E   +10 more
europepmc   +1 more source

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