Results 61 to 70 of about 88,763 (155)

Characterization of Runella slithyformis HD-Pnk, a Bifunctional DNA/RNA End-Healing Enzyme Composed of an N-Terminal 2′,3′-Phosphoesterase HD Domain and a C-Terminal 5′-OH Polynucleotide Kinase Domain

Journal of Bacteriology, 2016
Annum Munir, S. Shuman
semanticscholar   +1 more source

Tidying up loose ends: the role of polynucleotide kinase/phosphatase in DNA strand break repair.

TIBS -Trends in Biochemical Sciences. Regular ed, 2011
M. Weinfeld, Rajam S. Mani, I. Abdou, R. D. Aceytuno, J. Glover   +4 more
semanticscholar   +1 more source

RNA ligase RtcB splices 3′-phosphate and 5′-OH ends via covalent RtcB-(histidinyl)-GMP and polynucleotide-(3′)pp(5′)G intermediates

Proceedings of the National Academy of Sciences of the United States of America, 2012
A. Chakravarty, R. Subbotin, B. Chait, S. Shuman   +3 more
semanticscholar   +1 more source

Structural basis for the phosphatase activity of polynucleotide kinase/phosphatase on single- and double-stranded DNA substrates

Proceedings of the National Academy of Sciences of the United States of America, 2011
N. Coquelle, Zahra Havali-Shahriari, N. Bernstein, R. Green, J. Glover   +4 more
semanticscholar   +1 more source

Horizontal acquisition of a DNA ligase improves DNA damage tolerance in eukaryotes. [PDF]

Nat Commun, 2023
Nicolas E, Simion P, Guérineau M, Terwagne M, Colinet M, Virgo J, Lingurski M, Boutsen A, Dieu M, Hallet B, Van Doninck K.   +10 more
europepmc   +1 more source

Direct comparison of nick-joining activity of the nucleic acid ligases from bacteriophage T4.

Biochemical Journal, 2006
D. Bullard, R. Bowater
semanticscholar   +1 more source

Active site of the mRNA-capping enzyme guanylyltransferase from Saccharomyces cerevisiae: similarity to the nucleotidyl attachment motif of DNA and RNA ligases.

Proceedings of the National Academy of Sciences of the United States of America, 1994
L. D. Fresco, S. Buratowski
semanticscholar   +1 more source

Direct adenylation from 5'-OH-terminated oligonucleotides by a fusion enzyme containing Pfu RNA ligase and T4 polynucleotide kinase. [PDF]

Nucleic Acids Res, 2022
Yang Z, Zhang C, Lian G, Dong S, Song M, Shao H, Wang J, Zhong T, Luo Z, Jin S, Ding C.   +10 more
europepmc   +1 more source

Human polynucleotide kinase participates in repair of DNA double-strand breaks by nonhomologous end joining but not homologous recombination.

Cancer Research, 2007
Feridoun Karimi-Busheri, A. Rasouli-Nia, J. Allalunis-Turner, M. Weinfeld   +3 more
semanticscholar   +1 more source

Polynucleotide kinase as a potential target for enhancing cytotoxicity by ionizing radiation and topoisomerase I inhibitors.

Anti-Cancer Agents in Medicinal Chemistry, 2008
N. Bernstein, Feridoun Karimi-Busheri, A. Rasouli-Nia, R. Mani, G. Dianov, J. Glover, M. Weinfeld   +6 more
semanticscholar   +1 more source