Results 61 to 70 of about 16,842 (191)

The number of domains in the ribosomal protein S1 as a hallmark of the phylogenetic grouping of bacteria.

PLoS ONE, 2019
The family of ribosomal proteins S1 contains about 20% of all bacterial proteins including the S1 domain. An important feature of this family is multiple copies of structural domains in bacteria, the number of which changes in a strictly limited range ...
Andrey V Machulin, Evgenia I Deryusheva, Olga M Selivanova, Oxana V Galzitskaya   +3 more
doaj   +1 more source

Regulatory Mechanisms of Exoribonuclease PNPase and Regulatory Small RNA on T3SS of Dickeya dadantii

Molecular Plant-Microbe Interactions, 2010
The type III secretion system (T3SS) is an essential virulence factor for many bacterial pathogens. Polynucleotide phosphorylase (PNPase) is one of the major exoribonucleases in bacteria and plays important roles in mRNA degradation, tRNA processing, and
Quan Zeng, A. Mark Ibekwe, Eulandria Biddle, Ching-Hong Yang   +3 more
doaj   +1 more source

Strategies for Detecting Aminoacylation and Aminoacyl‐tRNA Editing in vitro and in Cells

Israel Journal of Chemistry, Volume 64, Issue 8-9, September 2024.
Abstract Aminoacyl‐tRNA synthetases (aaRSs) maintain translational fidelity by ensuring the formation of correct aminoacyl‐tRNA pairs. Numerous point mutations in human aaRSs have been linked to disease phenotypes. Structural studies of aaRSs from human pathogens encoding unique domains support these enzymes as potential candidates for therapeutics ...
Rylan R. Watkins, Arundhati Kavoor, Karin Musier‐Forsyth   +2 more
wiley   +1 more source

Bottom‐Up Synthesized Glucan Materials: Opportunities from Applied Biocatalysis

Advanced Materials, Volume 36, Issue 27, July 4, 2024.
Linear d‐glucans, simple yet versatile polysaccharides, shape nanostructures crucial for biomaterial development. Shifting from top‐down to bottom‐up synthesis using natural and engineered enzymes provides meticulous control over polymer structures, fostering diversification for macromolecular materials.
Chao Zhong, Bernd Nidetzky
wiley   +1 more source

Single‐Molecule Electrical Profiling of Peptides and Proteins

Advanced Science, Volume 11, Issue 28, July 24, 2024.
This work presents a timely overview of the prominent research progress in peptide and protein‐related studies through single‐molecule electrical techniques, including single‐molecule junction, single‐molecule field‐effect transistor (FET), and nanopore.
Hongyu Ju, Li Cheng, Mengmeng Li, Kunrong Mei, Suhang He, Chuancheng Jia, Xuefeng Guo   +6 more
wiley   +1 more source

The RNA processing enzyme polynucleotide phosphorylase negatively controls biofilm formation by repressing poly-N-acetylglucosamine (PNAG) production in Escherichia coli C

BMC Microbiology, 2012
Background Transition from planktonic cells to biofilm is mediated by production of adhesion factors, such as extracellular polysaccharides (EPS), and modulated by complex regulatory networks that, in addition to controlling production of adhesion ...
Carzaniga Thomas, Antoniani Davide, Dehò Gianni, Briani Federica, Landini Paolo   +4 more
doaj   +1 more source

Rat liver mitochondrial polynucleotide phosphorylase

FEBS Letters, 1971
We have recently isolated, partially purified and demonstrated the specificity of a polynucleotide phosphorylase from crude guinea-pig liver nuclei [ 1,2] The enzyme was associated with membrane lipids and catalysed the phosphorolysis of polyribonucleotides to ribonucleoside diphosphates.
See, Yew Phew, Fitt, P.S.
openaire   +2 more sources

Antibiotic influx and efflux in Pseudomonas aeruginosa: Regulation and therapeutic implications

Microbial Biotechnology, Volume 17, Issue 5, May 2024.
This work comprehensively summarized the regulatory networks of the major porin proteins and efflux pumps that play critical roles in antibiotic influx and efflux in Pseudomonas aeruginosa. It also discussed promising therapeutic approaches to combat multidrug‐resistant P.
Weiyan Wu, Jiahui Huang, Zeling Xu
wiley   +1 more source

Mechanism of action of streptomycin : studies with polynucleotide phosphorylase and ribosomes

, 1962
Some of the previous work on the mechanism of action of streptomycin has indicated the general area of nucleic acid metabolism as being a possible site of action.
Willick, Gordon Edward
core   +1 more source

JAK Inhibition in PNPT1‐Related Mitochondrial Interferonopathy: A Case Report and Review of Mitochondrial–Immune Crosstalk

JIMD Reports
Biallelic pathogenic variants in PNPT1 cause combined oxidative phosphorylation deficiency 13 (COXPD13) (MIM #614932), linking mitochondrial dysfunction to type I interferon (IFN) activation through cytosolic leakage of mitochondrial double‐stranded RNA (
Dan Ross Brooks, Hyun Yong Koh, Taylor Martin Kerrins, Steven Lang, Emily Bland, Rui Yang, Sarah Kogan Nicholas, Stephanie Jean Sikkink, Stephen Kralik, Christine Eng, Chaya Nautiyal Murali, Seema Lalani, Pilar Lenglet Magoulas, Lisa Emrick, Kristen Sydney Fisher, Fernando Scaglia   +15 more
doaj   +1 more source