Results 61 to 70 of about 6,571 (231)
Dose-Response, 2014 Low capacity runner (LCR) rats have been developed by divergent artificial selection for treadmill endurance capacity to explore an aerobic biology-disease connection.
Nikolett Hart +6 more
doaj +1 more source
Computational evolution of an RNA-binding protein towards enhanced oxidized-RNA binding
Computational and Structural Biotechnology Journal, 2020 The oxidation of RNA has been implicated in the development of many diseases. Among the four ribonucleotides, guanosine is the most susceptible to oxidation, resulting in the formation of 8-oxo-7,8-dihydroguanosine (8-oxoG). Despite the limited knowledge
Juan C. Gonzalez-Rivera +9 more
doaj +1 more source
Crystal structure of human polynucleotide phosphorylase: insights into its domain function in RNA binding and degradation. [PDF]
Nucleic Acids Res, 2012 Lin CL +4 more
europepmc +2 more sources
Human FASTK preferentially binds single‐stranded and G‐rich RNA
The FEBS Journal, Volume 293, Issue 3, Page 729-748, February 2026.Although FASTK is known to play a role in mRNA biology, the mechanism through which it recognizes RNA has yet to be unraveled. Here, we used purified human FASTK to characterize its RNA‐binding properties in vitro. We found that FASTK prefers ssRNA oligonucleotides containing guanines with the potential to form G‐quadruplexes and binds robustly to any ...
Daria M. Dawidziak +7 more
wiley +1 more source
Defects of mitochondrial RNA turnover lead to the accumulation of double-stranded RNA in vivo.
PLoS Genetics, 2019 The RNA helicase SUV3 and the polynucleotide phosphorylase PNPase are involved in the degradation of mitochondrial mRNAs but their roles in vivo are not fully understood.
Aleksandra Pajak +12 more
doaj +1 more source
Small Science, Volume 5, Issue 12, December 2025.This review highlights the advances in graphene liquid cell designs for in situ liquid‐phase transmission electron microscopy, spanning veil‐type, well‐type, liquid‐flowing‐type, and mixing‐type configurations. These developments collectively enable real‐time visualization of diverse reactions in liquid environments at atomic resolution, thereby ...
Hyeonjong Ma +2 more
wiley +1 more source
BMC Genomics, 2021 Background The polynucleotide phosphorylase (PNPase) is conserved among both Gram-positive and Gram-negative bacteria. As a core part of the Escherichia coli degradosome, PNPase is involved in maintaining proper RNA levels within the bacterial cell.
Daniel-Timon Spanka +2 more
doaj +1 more source
The relation of polynucleotide phosphorylase and growth of Escherichia coli [PDF]
, 1968 Call number: LD2668 .T4 1968 C443Master of ...
Chen, Amy H. M.
core
Sequence motifs that distinguish ATP(CTP) : tRNA nucleotidyl transferases from eubacterial poly(A) polymerases [PDF]
, 2004 ATP(CTP):tRNA nucleotidyl transferases, tRNA maturing enzymes found in all organisms, and eubacterial poly(A) polymerases, enzymes involved in mRNA degradation, are so similar that until now their biochemical functions could not be distinguished by their
Martin, G., Keller, W.
core +1 more source
Journal of Clinical Laboratory Analysis, Volume 39, Issue 2, January 2025.Analysis of real‐world cross‐sectional study data revealed relative errors between the standard method and ICP‐MS for the different minerals tested. Additionally, several outliers were observed exclusively in the ICP‐MS results, likely due to hemolysis or other unidentified factors.
Kosuke Kojo +10 more
wiley +1 more source