Results 81 to 90 of about 43,987 (256)

RNase E biomolecular condensates stimulate PNPase activity

Scientific Reports, 2023
Bacterial Ribonucleoprotein bodies (BR-bodies) play an essential role in organizing RNA degradation via phase separation in the cytoplasm of bacteria. BR-bodies mediate multi-step mRNA decay through the concerted activity of the endoribonuclease RNase E ...
Michael J. Collins, Dylan T. Tomares, Vidhyadhar Nandana, Jared M. Schrader, W. Seth Childers   +4 more
doaj   +1 more source

Genome wide association studies for acid phosphatase activity at varying phosphorous levels in Brassica juncea L

Frontiers in Plant Science, 2022
Acid phosphatases (Apases) are an important group of enzymes that hydrolyze soil and plant phosphoesters and anhydrides to release Pi (inorganic phosphate) for plant acquisition. Their activity is strongly correlated to the phosphorus use efficiency (PUE)
Priyanka Upadhyay, Mehak Gupta, Simarjeet Kaur Sra, Rakesh Sharda, Sanjula Sharma, Virender K. Sardana, Javed Akhatar, Gurpreet Kaur   +7 more
doaj   +1 more source

Maturation of Polycistronic mRNAs by the Endoribonuclease RNase Y and Its Associated Y-Complex in Bacillus Subtilis [PDF]

, 2018
Endonucleolytic cleavage within polycistronic mRNAs can lead to differential stability, and thus discordant abundance, among cotranscribed genes. RNase Y, the major endonuclease for mRNA decay in Bacillus subtilis, was originally identified for its ...
DeLoughery, Aaron, Lalanne, Jean-Benoit, Li, Gene-Wei, Losick, Richard   +3 more
core   +1 more source

Helicase SUV3, polynucleotide phosphorylase, and mitochondrial polyadenylation polymerase form a transient complex to modulate mitochondrial mRNA polyadenylated tail lengths in response to energetic changes. [PDF]

J Biol Chem, 2014
Background: Helicase SUV3, polynucleotide phosphorylase (PNPase), or mitochondrial poly(A) polymerases (mtPAP) have individual activity in regulating mitochondrial mRNA (mt-mRNA)-polyadenylated (poly(A)) tails.
Wang DD, Guo XE, Modrek AS, Chen CF, Chen PL, Lee WH.   +5 more
europepmc   +2 more sources

A PNPase dependent CRISPR System in Listeria. [PDF]

PLoS Genetics, 2014
The human bacterial pathogen Listeria monocytogenes is emerging as a model organism to study RNA-mediated regulation in pathogenic bacteria. A class of non-coding RNAs called CRISPRs (clustered regularly interspaced short palindromic repeats) has been ...
Nina Sesto, Marie Touchon, José Marques Andrade, Jiro Kondo, Eduardo P C Rocha, Cecilia Maria Arraiano, Cristel Archambaud, Éric Westhof, Pascale Romby, Pascale Cossart   +9 more
doaj   +1 more source

Analysis of mRNA Decay Intermediates in Bacillus subtilis 3′ Exoribonuclease and RNA Helicase Mutant Strains

mBio, 2022
The Bacillus subtilis genome encodes four 3′ exoribonucleases: polynucleotide phosphorylase (PNPase), RNase R, RNase PH, and YhaM. Previous work showed that PNPase, encoded by the pnpA gene, is the major 3′ exonuclease involved in mRNA turnover; in a ...
Shivani Chhabra, Zachary F. Mandell, Bo Liu, Paul Babitzke, David H. Bechhofer   +4 more
doaj   +1 more source

Sequence motifs that distinguish ATP(CTP) : tRNA nucleotidyl transferases from eubacterial poly(A) polymerases [PDF]

, 2004
ATP(CTP):tRNA nucleotidyl transferases, tRNA maturing enzymes found in all organisms, and eubacterial poly(A) polymerases, enzymes involved in mRNA degradation, are so similar that until now their biochemical functions could not be distinguished by their
Keller, W., Martin, G.
core   +2 more sources

The ribonuclease PNPase is a key regulator of biofilm formation in Listeria monocytogenes and affects invasion of host cells

npj Biofilms and Microbiomes, 2023
Biofilms provide an environment that protects microorganisms from external stresses such as nutrient deprivation, antibiotic treatments, and immune defences, thereby creating favorable conditions for bacterial survival and pathogenesis. Here we show that
Ana Patrícia Quendera, Sandra Nunes Pinto, Vânia Pobre, Wilson Antunes, Vasco D. B. Bonifácio, Cecília Maria Arraiano, José Marques Andrade   +6 more
doaj   +1 more source

Supernatants derived from chemotherapy-treated cancer cell lines can modify angiogenesis [PDF]

, 2012
BACKGROUND: There is evidence that tumours produce substances such as cytokines and microvesicular bodies bearing bioactive molecules, which support the carcinogenic process.
Bodman-Smith, M, Chanthirakumar, C, Coulton, G, Dalgleish, AG, Dennis, JL, Fowler, DW, Gravett, AM, Kaminska, E, Liu, WM   +8 more
core   +1 more source

Identification of Polynucleotide Phosphorylase (PNPase) in Escherichia coli Involved in Persister Formation

bioRxiv, 2018
Despite the identification of many genes and pathways involved in the persistence phenomenon of bacteria, the mechanisms of persistence are not well understood.
Nan Wu, Yumeng Zhang, Shanshan Zhang, Youhua Yuan, Shuang Liu, P. Cui, Wen Zhang, Ying Zhang   +7 more
semanticscholar   +1 more source