Results 81 to 90 of about 38,341 (274)

Light‐Responsive Mononucleotide Coacervates

open access: yesChemistry – A European Journal, EarlyView.
Light‐responsive mononucleotide coacervates undergo reversible phase transitions via azobenzene photoisomerization. Coacervates with high‐valency azobenzenes remain stable under UV light, while those with low‐valency azobenzenes dissolve, enabling nucleotide release. This minimal system highlights the potential role of light for exploring energy‐driven
Edison Rafael Jimenez Granda   +4 more
wiley   +1 more source

Randomised, double-blind comparison of a fixed co-formulation of intra-articular polynucleotides and hyaluronic acid versus hyaluronic acid alone in the treatment of knee osteoarthritis: two-year follow-up

open access: yesBMC Musculoskeletal Disorders, 2021
Background A first-year interim analysis of this two-year study suggested that intra-articular injections of highly purified, natural-origin polynucleotides and hyaluronic acid (HA) as a fixed combination (PNHA) might improve knee function and joint pain
Cesare Stagni   +9 more
doaj   +1 more source

Colloquium: Physical approaches to DNA sequencing and detection [PDF]

open access: yes, 2008
With the continued improvement of sequencing technologies, the prospect of genome-based medicine is now at the forefront of scientific research. To realize this potential, however, a revolutionary sequencing method is needed for the cost-effective and ...
Di Ventra, Massimiliano, Zwolak, Michael
core   +2 more sources

Analytical Study of Lanolin as Potential Biomarker of Prehistoric Sheep‐Shearing Practice

open access: yesChemistry–Methods, EarlyView.
Lanolin, a complex wax found on sheep wool, accumulates on shearing tools, such as flint and obsidian blades, used since the Neolithic. This study explores lanolin's degradation patterns as a potential biomarker for prehistoric sheep‐shearing practices, employing micro‐Fourier transformed infrared spectroscopy, hyperspectral imaging, and gas ...
Claudia Adsuar Fuster   +8 more
wiley   +1 more source

Study on Interaction of Cationic Porphyrazine with Synthetic Polynucleotides

open access: yesAnalytical Cellular Pathology, 2013
Interactions of cationic tetrakis (N, N′, N″, N‴- tetramethyltetra-3, 4-pyridinoporphyrazinatozinc (II) (Zn (tmtppa)) with synthetic polynucleotides, poly (G-C) and poly (A-T), and calf thymus DNA have been characterized in 7.5 mM phosphate buffer of pH ...
Hamid Dezhampanah, Soghra Fyzolahjani
doaj   +1 more source

Ribozyme Activity of RNA Nonenzymatically Polymerized from 3′,5′-Cyclic GMP

open access: yesEntropy, 2013
3′,5′-Cyclic GMP spontaneously nonenzymatically polymerizes in a base-catalyzed reaction affording G oligonucleotides. When reacted with fully or partially sequence-complementary RNA (oligo C), the abiotically generated oligo G RNA displays a typical ...
Samanta Pino   +5 more
doaj   +1 more source

DNA Renaturation at the Water-Phenol Interface [PDF]

open access: yes, 2003
We study DNA adsorption and renaturation in a water-phenol two-phase system, with or without shaking. In very dilute solutions, single-stranded DNA is adsorbed at the interface in a salt-dependent manner.
121   +161 more
core   +3 more sources

Exploring the Potential and Advancements of Circular RNA Therapeutics

open access: yesExploration, EarlyView.
Given the remarkable advantages in terms of stability, sustained expression profile, safety, wide range of druggable targets, scalable and cost‐effective manufacturing capabilities, circRNA is currently undergoing intensive investigation for various therapeutic applications such as vaccines, protein replacement, genetic disease treatment, gene therapy,
Lei Wang   +6 more
wiley   +1 more source

Activation of target-tissue immune-recognition molecules by double-stranded polynucleotides.

open access: yesProceedings of the National Academy of Sciences of the United States of America, 1999
Abnormal expression of major histocompatibility complex (MHC) class I and class II in various tissues is associated with autoimmune disease. Autoimmune responses can be triggered by viral infections or tissue injuries. We show that the ability of a virus
Koichi Suzuki   +7 more
semanticscholar   +1 more source

Viral Evolution and Adaptation as a Multivariate Branching Process [PDF]

open access: yes, 2011
In the present work we analyze the problem of adaptation and evolution of RNA virus populations, by defining the basic stochastic model as a multivariate branching process in close relation with the branching process advanced by Demetrius, Schuster and Sigmund ("Polynucleotide evolution and branching processes", Bull. Math. Biol. 46 (1985) 239-262), in
arxiv   +1 more source

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