The Pacific lineage (2E) of JC polyomavirus is prevalent in Sumba Island, Eastern Indonesia [PDF]
Recent studies have identified a Pacific lineage (2E) of JC polyomavirus (also designated as JC virus or JCV) that occurs in both Island Southeast Asia and Oceania, but not in mainland Asia.
Nakazawa, Minato +11 more
core +2 more sources
BKTyper: Free Online Tool for Polyoma BK Virus VP1 and NCCR Typing
Human BK polyomavirus (BKPyV) prevalence has been increasing due to the introduction of more potent immunosuppressive agents in transplant recipients, and its clinical interest. BKPyV has been linked mostly to polyomavirus-associated hemorrhagic cystitis,
Joan Martí-Carreras +5 more
doaj +1 more source
Histologic versus Molecular Diagnosis of BK Polyomavirus–Associated Nephropathy [PDF]
Although discovered in 1970 the BK virus infections had no significant clinical impact until the emergence of BK virus-associated allograft nephropathy (BKPVAN). Escalating clinical challenges required better diagnostic tools and delineation of uniform criteria for diagnosis.
Cinthia B, Drachenberg +2 more
openaire +2 more sources
BK Polyomavirus-Induced Nephropathy in Native Kidney
BK polyomavirus has been well-studied as an opportunistic infection in immunocompromised kidney transplant patients. In the majority of the population, BK polyomavirus establishes a lifelong infection in renal tubular and uroepithelial cells; however, in
Gupta, Nikhil +3 more
core +1 more source
BK polyomavirus: latency, reactivation, diseases and tumorigenesis
The identification of the first human polyomavirus BK (BKV) has been over half century, The previous epidemiological and phylogenetic studies suggest that BKV prevailed and co-evolved with humans, leading to high seroprevalence all over the world.
Xianfeng Zhou +4 more
doaj +1 more source
BK Polyomavirus in Renal Transplantation: Virological Notes for Monitoring and Diagnosis
Polyomavirus-associated nephropathy was first reported over 50 years ago. However, it still represents a cause of renal injury in kidney transplant recipients, particularly in the first two years post-transplantation, with occurrence rates of 1–10%.
Cristina Costa +3 more
doaj +1 more source
Cross‐Neutralizing and Broadly Neutralizing Human Antibodies Against Nonenveloped Viruses
In this review article, Marchand et al. compare cross ‐ and broadly ‐neutralizing human antibodies against non ‐ enveloped viruses from several major families, discussing their structural characteristics, neutralization mechanisms and relevance for the development of antiviral vaccines and therapeutics.
Sarah Marchand +2 more
wiley +1 more source
Polyomavirus Nephropathy in Kidney Transplantation
Polyomavirus nephropathy has become an important complication in kidney transplantation, with a prevalence of 1% to 8%. Unfortunately, the risk factors for polyomavirus nephropathy and renal allograft loss are not well defined.
Prabir Roy-Chaudhury +7 more
core +1 more source
Polyomavirus BK Nephropathy-Associated Transcriptomic Signatures: A Critical Reevaluation
Background. Recent work using DNA microarrays has suggested that genes related to DNA replication, RNA polymerase assembly, and pathogen recognition receptors can serve as surrogate tissue biomarkers for polyomavirus BK nephropathy (BKPyVN). Methods.
Ling Pan, MD +7 more
doaj +1 more source
Development of a droplet digital PCR assay for the detection of BK polyomavirus
The objective of this study was to establish a more sensitive and specific diagnostic method for detecting plasma BK polyomavirus (BKPyV) DNA load in patients after renal transplantation using droplet digital polymerase chain reaction (ddPCR) and to ...
Lu Ai +9 more
doaj +1 more source

