Results 31 to 40 of about 8,066,649 (187)
BMC Nephrology, 2021 Background Some studies have suggested mizoribine (MZR) could inhibit the replication of BK polyomavirus (BKPyV). The purpose of this study was to explore whether conversion from mycophenolate mofetil (MMF) to MZR in the early stages of BKPyV infection ...
Ping Li +6 more
doaj +1 more source
Glucocorticoids Do Not Enhance BK Polyomavirus Replication in Human Renal Proximal Tubular Epithelial Cells In Vitro. [PDF]
Clin Transl SciABSTRACT BK polyomavirus (BKPyV) infection may lead to BKPyV‐associated nephropathy (BKPyVAN) and subsequent graft loss in kidney transplant recipients. Experimental studies have suggested that glucocorticoids (GCs) may enhance BKPyV replication through a steroid‐responsive element within the viral genome.
Moest WT +7 more
europepmc +2 more sources
Polyomavirus BK with rearranged noncoding control region emerge in vivo in renal transplant patients and increase viral replication and cytopathology [PDF]
, 2008 Immunosuppression is required for BK viremia and polyomavirus BK-associated nephropathy (PVAN) in kidney transplants (KTs), but the role of viral determinants is unclear.
Hirsch, Hans H. +13 more
core +1 more source
Characterizing determinants of BK Polyomavirus-specific immune response [PDF]
, 2016 BK polyomavirus (BKPyV) is one of now 13 human polyomavirus (HPyV) species detected in humans. BKPyV is only known to infect humans and seroprevalence rates of more than 90% have been reported in adult populations around the world.
Cioni, Michela
core +1 more source
Microbiologia Medica, 2016 Polyomavirus-associated nephropathy is an important cause of allograft dysfunction and graft loss after kidney transplantation. Even if histological evaluation is the gold standard for graft study and diagnosis of polyomavirus-associated nephropathy, K ...
Antonio Curtoni +8 more
doaj +1 more source
JC and BK polyomavirus-like particles as targets of innate and adaptive humoral immunity [PDF]
, 2015 JC polyomavirus (JCPyV) and BK polyomavirus (BKPyV) were identified as the first of now more than 12 human polyomaviruses (HPyVs). The average JCPyV and BKPyV seroprevalence rates in adults are 70% and 90%, respectively. After asymptomatic infection both
Kardas, Piotr
core +1 more source
Transplantation Direct, 2022 Background:. Screening for polyomavirus infection after kidney transplantation is recommended by clinical practice guidelines, but cost-effectiveness of this strategy is uncertain.
Germaine Wong, PhD +5 more
doaj +1 more source
Polyomavirus BK-specific cellular immune response in Kidney transplant recipients [PDF]
, 2007 Polyomavirus BK is an emerging pathogen in KT recipients. New potent immunosuppressive drugs promote reactivation and replication of BKV and progression towards PVAN.
Binggeli, Simone Young
core +1 more source
In vitro and in vivo characterization of the cytomegalovirus and polyomavirus BK specific immune response [PDF]
, 2008 During my PhD thesis several aspects of the interaction of Cytomegalovirus and Polyomavirus BK with the host’s immune system were examined (see list of publications).
Egli, Adrian
core +1 more source
Polyomavirus-Associated Nephropathy
Medicine, 2011 Polyomavirus-associated nephropathy (PVAN) is an increasing cause of renal allograft dysfunction, but the optimal management of immunosuppression for these patients is unclear. We examined the clinical course of 58 patients with biopsy-proven PVAN diagnosed from 1997 to 2008 at Johns Hopkins Medical Institutions.
Duvuru, Geetha +4 more
openaire +2 more sources