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BK polyomavirus-associated nephropathy [PDF]

open access: yesChildhood Kidney Diseases, 2022
BK polyomavirus (BKPyV) is a ubiquitous virus residing in the kidney tubules and is clinically significant only in immunocompromised patients. In clinical practice, BKPyV is a causative pathogen of BKPyV-associated nephropathy (BKVAN) in kidney allograft
Yo Han Ahn, Hee Gyung Kang
doaj   +4 more sources

BK Polyomavirus-associated nephropathy - diagnostic and treatment standard. [PDF]

open access: yesNephrol Dial Transplant
ABSTRACT BK polyomavirus (BKPyV) is recognized as a significant viral complication of kidney transplantation. Prompt immunosuppression reduction reduces early graft failure rates due to BK polyomavirus-associated nephropathy (BKPyVAN), however, modulation of immunosuppression can lead to acute rejection.
Al-Talib M   +3 more
europepmc   +9 more sources

BK polyomavirus nephropathy in two kidney transplant patients with distinct diagnostic strategies for BK virus and similar clinical outcomes: two case reports

open access: yesJournal of Medical Case Reports, 2017
Background BK polyomavirus-associated nephropathy is an important cause of post-transplantation renal failure. We present two cases of BK polyomavirus-associated nephropathy who were submitted to contrasting strategies of clinical follow-up to BK ...
Ana Luisa Figueira Gouvêa   +10 more
doaj   +2 more sources

Leflunomide and Polyomavirus-Associated Nephropathy in Renal Transplant [PDF]

open access: yes, 2009
Polyomavirus nephropathy is a major complication in renal transplantation, associated with renal allograft loss in 14 to 80% of cases. There is no established treatment, although improvement has been reported with a variety of approaches. The authors report two cases of polyomavirus infection in renal allograft recipients.
Ferreira, AC   +6 more
core   +3 more sources

BK Polyomavirus-Associated Nephropathy and Hemorrhagic Cystitis in Transplant Recipients—What We Understand and What Remains Unclear [PDF]

open access: yesViruses
The reactivation of BK polyomavirus (BKPyV) during severe immunosuppression plays a crucial role in two significant syndromes observed in transplant recipients: BK polyomavirus-associated nephropathy (BKPyVAN) in kidney transplant patients and BK ...
Tang-Her Jaing   +2 more
doaj   +2 more sources

BK polyomavirus microRNA expression and sequence variation in polyomavirus-associated nephropathy [PDF]

open access: yesJournal of Clinical Virology, 2018
BK polyomavirus (BKPyV) infection is a common asymptomatic viral infection in the general population. Severe complications are seen in immunocompromised individuals, such as polyomavirus-associated nephropathy (PyVAN) in renal transplant recipients. Information on BKPyV microRNA expressions is scarce, although polyomavirus-encoded microRNAs have been ...
Virtanen, Elina   +8 more
openaire   +4 more sources

Polyomavirus – an emergent pathogen in transplant recipients [PDF]

open access: yesEinstein (São Paulo), 2007
Medical centers that work with transplants often face opportunisticinfections that demand specific tools to make diagnosis. Theprevalence of latent polyomavirus infections is high, and the mostcommon site of latency of the most prevalent polyomavirus in ...
Juliana de Moura Montagner   +8 more
doaj   +1 more source

Cellular immunity in BK polyomavirus associated nephropathy following adult kidney transplantation

open access: yesTransplantation Reports, 2022
Background: BK polyomavirus (BKPyV) is the most important polyomavirus affecting renal transplant recipients. BKPyV associated nephropathy (BKVAN) is seen in about 5% of renal transplant patients and can lead to graft loss in up to 50% of cases ...
Laila Schneidewind   +5 more
doaj   +2 more sources

BK Polyomavirus-specific T cell immune responses in kidney transplant recipients diagnosed with BK Polyomavirus-associated nephropathy [PDF]

open access: yesBMC Infectious Diseases, 2019
Background Adjustment of immunosuppression is the main therapy for BK polyomavirus (BKPyV)-associated nephropathy (BKPyVAN) after kidney transplantation (KT). Studies of BKPyV-specific T cell immune response are scarce.
Jackrapong Bruminhent   +7 more
doaj   +2 more sources

Polyomavirus specific cellular immunity: from BK-virus-specific cellular immunity to BK-virus-associated nephropathy ? [PDF]

open access: yesFrontiers in Immunology, 2015
In renal transplantation, BK-virus-associated nephropathy has emerged as a major complication, with a prevalence of 5–10% and graft loss in >50% of cases. BK-virus is a member of the Polyomavirus family and rarely induces apparent clinical disease in the
manon edekeyser   +3 more
doaj   +2 more sources

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