Results 61 to 70 of about 22,086 (184)

Anion homeostasis is important for non-lytic release of BK polyomavirus from infected cells [PDF]

Open Biology, 2015
BK polyomavirus (BKPyV) is a member of a family of potentially oncogenic viruses, whose reactivation can cause severe pathological conditions in transplant patients, leading to graft rejection. As with many non-enveloped viruses, it is assumed that virus
Gareth L. Evans, Laura G. Caller, Victoria Foster, Colin M. Crump   +3 more
doaj   +1 more source

An Accurate Genetic Colocalisation Method for the HLA Locus

HLA, Volume 107, Issue 5, May 2026.
ABSTRACT Genetic colocalisation analyses are frequently conducted to determine if causal signals at a genetic locus are shared between two phenotypes. However, colocalisation is rarely undertaken at the HLA locus, due to its complex linkage disequilibrium (LD) and high polymorphism density.
Guillaume Butler‐Laporte, Tianyuan Lu, Sam Morris, Wenmin Zhang, Gavin Band, Fergus Hamilton, Amanda Chong, Kuang Lin, Ruth Nanjala, J. Brent Richards, Mei‐Hsuan Lee, Ling Yang, Pang Yao, Liming Li, Zhengming Chen, Yang Luo, Iona Y. Millwood, Robin G. Walters, Alexander J. Mentzer   +18 more
wiley   +1 more source

Frequency of Polyomavirus BK Infection in Kidney Transplant Patients Suspected to Nephropathy

International Journal of Organ Transplantation Medicine, 2015
Background: Polyomavirus BK is a major cause of nephropathy in immunosuppressed transplanted patients. Non-invasive diagnostic protocols such as molecular detection of polyomavirus BK replication are a useful strategy to predict BK virus-associated ...
M Pakfetrat, R Yaghobi, Z Salmanpoor, J Roozbeh, S Torabinezhad, S Kadkhodaei   +5 more
doaj  

The Role of Merkel Cell Polyomavirus and Other Human Polyomaviruses in Emerging Hallmarks of Cancer

Viruses, 2015
Polyomaviruses are non-enveloped, dsDNA viruses that are common in mammals, including humans. All polyomaviruses encode the large T-antigen and small t-antigen proteins that share conserved functional domains, comprising binding motifs for the tumor ...
Ugo Moens, Kashif Rasheed, Ibrahim Abdulsalam, Baldur Sveinbjørnsson   +3 more
doaj   +1 more source

Manufacturing and clinical applications of non‐CAR‐T immune effector cells

Transfusion, EarlyView.
Thane Kubik, Theodros Mamo, David H. McKenna   +2 more
wiley   +1 more source

Beyond Human Papillomavirus (HPV): Detection of EBV and Polyomaviruses in Cervical and Anal Samples

Journal of Medical Virology, Volume 98, Issue 4, April 2026.
ABSTRACT Colorectal and cervical cancers represent an important public health problem worldwide, particularly in Brazil. Colorectal cancer is one of the most frequently diagnosed malignancies worldwide and the most common cancer in both men and woman in Brazil.
Ana Carolina Silva Guimarães, Luana L. S. Rodrigues, Letícia Bomfim Campos, Katrini G. Martinelli, Nathália Silva Carlos Oliveira, W. Martin Kast, Charlotte A. Gaydos, Carlos Silva de Jesus, José H. Pilotto, Mariza G. Morgado, Tarik Gheit, Vanessa Salete de Paula   +11 more
wiley   +1 more source

Epigenetic regulation of polyomavirus JC [PDF]

Virology Journal, 2013
Abstract Background Polyomavirus JC (JCV) causes the CNS demyelinating disease progressive multifocal leukoencephalopathy (PML), which occurs almost exclusively in people with immune deficiencies, such as HIV-1/AIDS patients. JCV infection is very common and usually occurs early in life. After primary infection, virus
Wollebo, Hassen S, Woldemichaele, Baheru, Khalili, Kamel, Safak, Mahmut, White, Martyn K   +4 more
openaire   +2 more sources

Neoadjuvant therapy in skin cancer: current evidence and future perspectives

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 24, Issue 4, Page 454-462, April 2026.
Summary The development of immune checkpoint inhibitors and targeted therapies has fundamentally changed the treatment of cutaneous malignancies, especially in squamous cell carcinoma, melanoma, and Merkel cell carcinoma. The latest neoadjuvant approaches have shown promising results in locally advanced stages.
Lea Daniello, Johannes Kleemann, Bastian Schilling   +2 more
wiley   +1 more source

Glycosphingolipids as Receptors for Non-Enveloped Viruses

Viruses, 2010
Glycosphingolipids are ubiquitous molecules composed of a lipid and a carbohydrate moiety. Their main functions are as antigen/toxin receptors, in cell adhesion/recognition processes, or initiation/modulation of signal transduction pathways.
Stefan Taube, Mengxi Jiang, Christiane E. Wobus   +2 more
doaj   +1 more source

Neoadjuvante Therapie bei Hautkrebs: aktuelle Datenlage und Ausblicke

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 24, Issue 4, Page 454-463, April 2026.
Zusammenfassung Die Entwicklung von Immuncheckpoint‐Inhibitoren sowie zielgerichteten Therapien hat die Behandlung von Hauttumoren, vor allem des kutanen Plattenepithelkarzinoms, Melanoms und Merkelzellkarzinoms, grundlegend verändert. Neuste neoadjuvante Ansätze zeigen besonders bei lokal fortgeschrittenen Stadien nun praxisrelevante Ergebnisse.
Lea Daniello, Johannes Kleemann, Bastian Schilling   +2 more
wiley   +1 more source