Results 61 to 70 of about 32,631 (184)

Cross‐Neutralizing and Broadly Neutralizing Human Antibodies Against Nonenveloped Viruses

European Journal of Immunology, Volume 56, Issue 10, October 2026.
In this review article, Marchand et al. compare cross ‐ and broadly ‐neutralizing human antibodies against non ‐ enveloped viruses from several major families, discussing their structural characteristics, neutralization mechanisms and relevance for the development of antiviral vaccines and therapeutics.
Sarah Marchand, Samy Taouli, Dorian McIlroy   +2 more
wiley   +1 more source

First Phylodynamic Analysis of HRSV‐A and HRSV‐B in Rio de Janeiro, Brazil, Reveals Recurrent Dispersals From the Megalopolis Center to Suburban Cities

Journal of Medical Virology, Volume 98, Issue 10, October 2026.
ABSTRACT Human respiratory syncytial virus (HRSV) is the leading cause of acute lower respiratory tract infections in infants and represents a major burden to public health systems worldwide. Despite its epidemiological relevance, genomic surveillance of HRSV in Brazil remains limited.
Alessandra Pavan Lamarca, Melise Chaves Silveira, Renata Campos Azevedo, Maria Angélica Arpon Marandino Guimarães, Claudia Maria Braga de Mello, Adriana Cardoso Camargo, Leandro Magalhães de Souza, Alexandra Lehmkuhl Gerber, Ana Paula C. Guimarães, Andréa Cony Cavalcanti, Ana Tereza Ribeiro Vasconcelos   +10 more
wiley   +1 more source

Characterization of six Merkel cell polyomavirus‐positive Merkel cell carcinoma cell lines: Integration pattern suggest that large T antigen truncating events occur before or during integration

International Journal of Cancer, 2019
Merkel cell carcinoma (MCC), an aggressive neuroendocrine skin tumor, is a polyomavirus‐induced human cancer. To study the causal relationship of MCC carcinogenesis with the integrated Merkel cell polyomavirus (MCPyV) in detail, well‐characterized MCC ...
D. Schrama, Eva-Maria Sarosi, Christian Adam, Cathrin Ritter, U. Kaemmerer, E. Klopocki, Eva-Maria König, J. Utikal, J. Becker, R. Houben   +9 more
semanticscholar   +1 more source

Novel Polyomaviruses in Mammals from Multiple Orders and Reassessment of Polyomavirus Evolution and Taxonomy

Viruses, 2019
As the phylogenetic organization of mammalian polyomaviruses is complex and currently incompletely resolved, we aimed at a deeper insight into their evolution by identifying polyomaviruses in host orders and families that have either rarely or not been ...
Bernhard Ehlers, Augustin E. Anoh, Nicole Ben Salem, Sebastian Broll, Emmanuel Couacy-Hymann, Daniela Fischer, Alma Gedvilaite, Nanina Ingenhütt, Sonja Liebmann, Maite Martin, Arsene Mossoun, Lawrence Mugisha, Jean-Jacques Muyembe-Tamfum, Maude Pauly, Bernat Pérez de Val, Hannah Preugschas, Dania Richter, Grit Schubert, Claudia A. Szentiks, Tamara Teichmann, Cornelia Walter, Rainer G. Ulrich, Lidewij Wiersma, Fabian H. Leendertz, Sébastien Calvignac-Spencer   +24 more
doaj   +1 more source

Type O blood group associates with higher anti‐JC polyomavirus antibody levels

Brain and Behavior, 2021
Background Patients with multiple sclerosis (MS) and high anti‐JC polyomavirus (JCPyV) antibodies in blood have an increased risk for the development of progressive multifocal leukoencephalopathy (PML) when treated for MS.
Pia Frenken, Hans‐Peter Hartung, Tomas Olsson, Ortwin Adams, Clemens Warnke   +4 more
doaj   +1 more source

Polyomavirus-positive Merkel cell carcinoma derived from a trichoblastoma suggests an epithelial origin of this Merkel cell carcinoma.

Journal of Investigative Dermatology, 2019
Merkel cell carcinoma (MCC), an aggressive neuroendocrine carcinoma of the skin, is to date the only human cancer known to be frequently caused by a polyomavirus. However, it is a matter of debate which cells are targeted by the Merkel cell polyomavirus (
T. Kervarrec, M. Aljundi, S. Appenzeller, M. Samimi, E. Maubec, B. Cribier, L. Deschamps, B. Sarma, Eva-Maria Sarosi, P. Berthon, A. Lévy, G. Bousquet, A. Tallet, A. Touzé, S. Guyétant, D. Schrama, R. Houben   +16 more
semanticscholar   +1 more source

A highly potent human antibody neutralizing all serotypes of BK polyomavirus.

PLoS Pathogens
BK polyomavirus infection poses a significant risk to kidney transplant recipients. Reactivation of dormant virus in the transplanted kidney, triggered by immunosuppression, can lead to BK polyomavirus-associated nephropathy in up to 10% of transplants ...
Marcel Weber, Simone Schmitt, Barbara Eicher, Jemima Seidenberg, Justina Rutkauskaite, Benedikt Stöckli, Catherine Townsend, Uyen Huynh-Do, Thomas Schachtner, Serena Delbue, Armin Mäder, Christoph Esslinger, Matthias Hillenbrand   +12 more
doaj   +1 more source

The Role of Merkel Cell Polyomavirus and Other Human Polyomaviruses in Emerging Hallmarks of Cancer

Viruses, 2015
Polyomaviruses are non-enveloped, dsDNA viruses that are common in mammals, including humans. All polyomaviruses encode the large T-antigen and small t-antigen proteins that share conserved functional domains, comprising binding motifs for the tumor ...
Ugo Moens, Kashif Rasheed, Ibrahim Abdulsalam, Baldur Sveinbjørnsson   +3 more
doaj   +1 more source

Merkel cell polyomavirus recruits MYCL to the EP400 complex to promote oncogenesis

PLoS Pathogens, 2017
Merkel cell carcinoma (MCC) frequently contains integrated copies of Merkel cell polyomavirus DNA that express a truncated form of Large T antigen (LT) and an intact Small T antigen (ST).
Jingwei Cheng, D. Park, C. Berrios, E. White, Reety Arora, Rosa Yoon, T. Branigan, T. Xiao, T. Westerling, A. Federation, Rhamy Zeid, Ben Strober, S. Swanson, L. Florens, J. Bradner, Myles A. Brown, P. Howley, M. Padi, M. Washburn, J. DeCaprio   +19 more
semanticscholar   +1 more source

Anion homeostasis is important for non-lytic release of BK polyomavirus from infected cells [PDF]

Open Biology, 2015
BK polyomavirus (BKPyV) is a member of a family of potentially oncogenic viruses, whose reactivation can cause severe pathological conditions in transplant patients, leading to graft rejection. As with many non-enveloped viruses, it is assumed that virus
Gareth L. Evans, Laura G. Caller, Victoria Foster, Colin M. Crump   +3 more
doaj   +1 more source