Results 51 to 60 of about 36,847 (227)

From Data to Decisions: How Machine Learning and Generative Artificial Intelligence Are Redefining Precision Medicine in Kidney Transplantation

open access: yesOrgan Medicine, EarlyView.
This review evaluates how machine learning, multimodal integration, and generative AI optimize kidney transplant outcomes. These tools enable superior prediction and personalized therapy but face hurdles in data volume, generalizability, and ethics. Future clinical adoption depends on continued innovation and multidisciplinary collaboration to overcome
Maoxin Liao, Cheng Yang
wiley   +1 more source

Merkel Cell Polyomavirus DNA in Respiratory Specimens from Children and Adults

open access: yesEmerging Infectious Diseases, 2009
Merkel cell polyomavirus (MCPyV) DNA was detected in 7 (1.3%) of 526 respiratory tract samples from patients in Australia with upper or lower respiratory tract symptoms.
Seweryn Bialasiewicz   +4 more
doaj   +1 more source

Paediatric renal transplantation: Paediatric surgeons' perspective

open access: yesSurgical Practice, EarlyView.
Abstract Renal transplantation is the most effective treatment for paediatric end‐stage renal disease (ESRD), offering advantages in survival, growth and neurocognitive development that surpass other renal replacement therapies (RRT). The paediatric setting, however, introduces distinct complexities that distinguish it from adult practice.
Adrian Chi‐heng Fung   +3 more
wiley   +1 more source

Polyomavirus genome and polyomavirus enhancer-driven gene expression during myogenesis [PDF]

open access: yesJournal of Virology, 1989
The mRNAs for myogenic functions are coordinately transcribed with polyomavirus (Py) early mRNA during in vitro differentiation of mouse C2 myoblast cells. Sequence analysis shows that the A domain of the Py enhancer includes an E1A-like consensus sequence that is also found in the 5' upstream region of two genes expressed during myoblast ...
MAIONE, Rossella   +4 more
openaire   +3 more sources

Absence of DNA viruses in ameloblastomas

open access: yesEuropean Journal of Oral Sciences, EarlyView.
Abstract Ameloblastomas (ABs) are rare odontogenic benign tumors. Although studies of the molecular pathogenesis have revealed the presence of mutations and altered gene expression, the etiology is unresolved. Viruses cause 10%–15 % of cancers, but their potential role within benign tumors is less studied.
Maria K. Jauhiainen   +5 more
wiley   +1 more source

Production of recombinant VP1-derived virus-like particles from novel human polyomaviruses in yeast [PDF]

open access: yes, 2015
Background: Eleven new human polyomaviruses (HPyVs) have been identified in the last decade. Serological studies show that these novel HPyVs sub-clinically infect humans at an early age.
Alma Gedvilaite   +5 more
core   +1 more source

Antiviral regulator TRIM25 as a prognostic marker of better survival in Merkel cell carcinoma: Association with MCPyV status

open access: yesInternational Journal of Cancer, Volume 158, Issue 12, Page 3268-3278, 15 June 2026.
What's new? TRIM25 is known for its role in antiviral immunity and association with poor prognosis in various cancers. This study reveals an association between high TRIM25 expression and Merkel cell polyomavirus positivity in Merkel cell carcinoma.
Klaus W. Fagerstedt   +6 more
wiley   +1 more source

Polyomavirus T Antigen Induces APOBEC3B Expression Using an LXCXE-Dependent and TP53-Independent Mechanism

open access: yesmBio, 2019
APOBEC3B is a single-stranded DNA cytosine deaminase with beneficial innate antiviral functions. However, misregulated APOBEC3B can also be detrimental by inflicting APOBEC signature C-to-T and C-to-G mutations in genomic DNA of multiple cancer types ...
Gabriel J. Starrett   +13 more
doaj   +1 more source

mSphere of Influence: It’s Not Me, It’s You—How Donor Factors Influence Kidney Transplant Outcomes

open access: yesmSphere, 2020
Diana V. Pastrana works in the field of DNA tumor virus biology. In this mSphere of Influence article, she reflects on how the two papers “Donor origin of BKV replication after kidney transplantation” (C. Schmitt, L. Raggub, S. Linnenweber-Held, O. Adams,
Diana Valeria Pastrana
doaj   +1 more source

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