Results 71 to 80 of about 36,847 (227)

An enhancer of recombination in polyomavirus DNA [PDF]

Journal of Virology, 1996
Previous work from this laboratory has indicated that intramolecular homologous recombination of polyomavirus (Py) DNA is dependent upon promoter structure or function. In this report, we demonstrate that Py DNA contains not two but three binding sites for transcription factor YY1, all located on the late side of viral origin of replication (ori) and ...
D, Gendron, L, Delbecchi, D, Bourgaux-Ramoisy, P, Bourgaux   +3 more
openaire   +2 more sources

Beyond Human Papillomavirus (HPV): Detection of EBV and Polyomaviruses in Cervical and Anal Samples

Journal of Medical Virology, Volume 98, Issue 4, April 2026.
ABSTRACT Colorectal and cervical cancers represent an important public health problem worldwide, particularly in Brazil. Colorectal cancer is one of the most frequently diagnosed malignancies worldwide and the most common cancer in both men and woman in Brazil.
Ana Carolina Silva Guimarães, Luana L. S. Rodrigues, Letícia Bomfim Campos, Katrini G. Martinelli, Nathália Silva Carlos Oliveira, W. Martin Kast, Charlotte A. Gaydos, Carlos Silva de Jesus, José H. Pilotto, Mariza G. Morgado, Tarik Gheit, Vanessa Salete de Paula   +11 more
wiley   +1 more source

A highly potent human antibody neutralizing all serotypes of BK polyomavirus.

PLoS Pathogens
BK polyomavirus infection poses a significant risk to kidney transplant recipients. Reactivation of dormant virus in the transplanted kidney, triggered by immunosuppression, can lead to BK polyomavirus-associated nephropathy in up to 10% of transplants ...
Marcel Weber, Simone Schmitt, Barbara Eicher, Jemima Seidenberg, Justina Rutkauskaite, Benedikt Stöckli, Catherine Townsend, Uyen Huynh-Do, Thomas Schachtner, Serena Delbue, Armin Mäder, Christoph Esslinger, Matthias Hillenbrand   +12 more
doaj   +1 more source

Neoadjuvant therapy in skin cancer: current evidence and future perspectives

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 24, Issue 4, Page 454-462, April 2026.
Summary The development of immune checkpoint inhibitors and targeted therapies has fundamentally changed the treatment of cutaneous malignancies, especially in squamous cell carcinoma, melanoma, and Merkel cell carcinoma. The latest neoadjuvant approaches have shown promising results in locally advanced stages.
Lea Daniello, Johannes Kleemann, Bastian Schilling   +2 more
wiley   +1 more source

Frequency of Polyomavirus BK Infection in Kidney Transplant Patients Suspected to Nephropathy

International Journal of Organ Transplantation Medicine, 2015
Background: Polyomavirus BK is a major cause of nephropathy in immunosuppressed transplanted patients. Non-invasive diagnostic protocols such as molecular detection of polyomavirus BK replication are a useful strategy to predict BK virus-associated ...
M Pakfetrat, R Yaghobi, Z Salmanpoor, J Roozbeh, S Torabinezhad, S Kadkhodaei   +5 more
doaj  

Cancer vaccines: uses of HLA transgenic mice compared to genetically modified mice [PDF]

, 2008
Many tumor antigens have been identified that can be targeted by the immune system. Animal models that have been genetically modified to express human HLA molecules instead of their own MHC antigens have shown to be valuable in the discovery of peptides ...
McArdle, SE
core  

Intrachromosomal recombination mediated by the polyomavirus large T antigen [PDF]

, 1995
We used a spleen necrosis virus-based retroviral vector to introduce the polyomavirus replication origin into rat cells and developed a system to analyze homologous recombination events that do not reconstitute a selectable marker.
Alt, Asselin, Bastin, Bird, Botchan, Bouchard, Bouchard, Bouchard, Cegielska, Colantuoni, Dornreiter, Dougherty, Hirt, Israel, Land, Larose, Liskay, Miller, Pall, Pellegrini, Roberge, Scheidtmann, Scheidtmann, Schimke, Shah, Southern, Spradling, St-Onge, St-Onge, St-Once, St-Onge, Thomas, Tlsty, Varshavski, Wang, Watanabe   +35 more
core   +1 more source

A Novel Polyomavirus (Goose Hemorrhagic Polyomavirus) Is the Agent of Hemorrhagic Nephritis Enteritis of Geese [PDF]

Journal of Virology, 2000
ABSTRACT We have identified the etiological agent of hemorrhagic nephritis enteritis of geese (HNEG), a fatal disease of European geese. HNEG has been recognized in almost all goose breeding areas, with an epizootic pattern, and up to now, the infectious agent has remained unknown.
Guerin, J.L., Gelfi, Jacqueline, Dubois, Loic, Vuillaume, Adeline, Boucraut-Baralon, Corine, Pingret, J.L.   +5 more
openaire   +3 more sources

Neoadjuvante Therapie bei Hautkrebs: aktuelle Datenlage und Ausblicke

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 24, Issue 4, Page 454-463, April 2026.
Zusammenfassung Die Entwicklung von Immuncheckpoint‐Inhibitoren sowie zielgerichteten Therapien hat die Behandlung von Hauttumoren, vor allem des kutanen Plattenepithelkarzinoms, Melanoms und Merkelzellkarzinoms, grundlegend verändert. Neuste neoadjuvante Ansätze zeigen besonders bei lokal fortgeschrittenen Stadien nun praxisrelevante Ergebnisse.
Lea Daniello, Johannes Kleemann, Bastian Schilling   +2 more
wiley   +1 more source

Detection and differentiation of human polyomaviruses JC and BK by LightCycler PCR [PDF]

, 2001
Human polyomaviruses JC and BK may cause several clinical manifestations in immunocompromised hosts, including progressive multifocal leukoencephalopathy and hemorrhagic cystitis.
Whiley, David M., Mackay, Ian M., Sloots, Theo P.   +2 more
core   +1 more source