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BK Polyomavirus-Associated Urothelial Carcinoma of the Bladder with a Background of BK Polyomavirus Nephropathy in a Kidney Transplant Recipient

Nephron, 2023
Renal transplant recipients are at increased risk for the development of a malignant neoplasm. Polyomavirus-associated urothelial carcinoma is a rare tumor that occurs in renal transplant recipients, with approximately 41 cases reported since 2002. It accounts for 27–31% of all post-transplant urothelial carcinomas and develops at an average of 8.5 ...
Sari Iwasaki   +9 more
openaire   +2 more sources

Transplacental transmission of human polyomavirus BK

Journal of Medical Virology, 1998
The presence of BK virus (BKV) and JC virus (JCV) in autopsy materials (placenta, brain, and kidney) of aborted fetuses was investigated by PCR using two sets of primers, specific for the regulatory region (RR) and for the capsid protein VP1, respectively.
PIETROPAOLO, Valeria Antonietta   +7 more
openaire   +3 more sources

Leflunomide for Polyomavirus Type BK Nephropathy

New England Journal of Medicine, 2005
To the Editor: Polyomavirus type BK nephropathy is an aggressively destructive disease occurring in up to 8 percent of patients with renal allografts,1,2 with rates of graft loss within one year of 30 to 65 percent.3,4 There is no therapy with proven efficacy.
James W, Williams   +11 more
openaire   +2 more sources

BK polyomavirus

Journal of Kidney Care
This article outlines what a patient needs to know about the BK polyomavirus and how it can effect a kidney transplant
Simon Baker   +2 more
openaire   +1 more source

Update on human polyomavirus BK nephropathy

Diagnostic Cytopathology, 2009
AbstractPolyomavirus BK (BKV) has ebeen identified as the main cause of polyomavirus‐associated nephropathy, a major cause of renal allograft failure. Although BKV‐associated nephropathy develops in only 2% to 5% of renal transplant recipients, its prognosis when present is very poor, with irreversible graft failure developing in 45% of affected ...
David, Cimbaluk   +3 more
openaire   +2 more sources

Immunosuppression, BK polyomavirus infections, and BK polyomavirus-specific T cells after pediatric kidney transplantation

Pediatric Nephrology, 2019
After kidney transplantation, immunosuppressive therapy increases risk of BK polyomavirus-associated nephropathy (BKPyVAN). Outcomes of BKPyV viremia are various and prognostic markers are missing. The impact of different immunosuppressive regimens on BKPyV infections is currently under discussion.We analyzed immunosuppressive therapy and BKPyV ...
Thurid Ahlenstiel-Grunow, Lars Pape
openaire   +2 more sources

BK Polyomavirus Infection in the Renal Transplant Recipient

Infectious Disease Clinics of North America, 2013
Renal transplant recipients continue to have progressive kidney dysfunction and renal graft loss has been attributed to emerging opportunistic infections, specifically BK virus (BKV). BKV is postulated to be selected by the new potent immunosuppressive medications and to be an important factor in graft failure.
Gayle P, Balba   +2 more
openaire   +2 more sources

Polyomavirus BK in the pathogenesis of bladder cancer.

The Netherlands journal of medicine, 2013
Polyomaviruses are able to drive malignant transformation in rodent models, and have been implicated in the aetiology of a variety of human malignancies. However, the reports on this association in humans are strongly conflicting. Here we describe a renal transplant (RT) recipient with ureteral stenosis against the background of polyomavirus BK (BKV ...
van Aalderen, M. C.   +7 more
openaire   +2 more sources

Polyomavirus BK-Specific Immunity after Kidney Transplantation

Transplantation, 2004
Failure to mount or maintain a protective immune response may influence the development of polyomavirus BK (BKV)-associated nephropathy (PVAN). However, limited data are so far available on BKV-specific immunity after kidney transplantation. BKV-specific cellular immune response was retrospectively analyzed in kidney recipients with or without BKV ...
COMOLI P   +12 more
openaire   +4 more sources

Polyomavirus BK infection in Greek renal transplant recipients

Transplantation Proceedings, 2004
BK polyoma virus associated nephropathy is increasingly recognized as an important cause of allograft dysfunction among renal transplant recipients. Herein we present the cases of two renal transplant recipients who developed progressive functional deterioration suspicious for BK polyoma virus involvement.
G, Zavos   +7 more
openaire   +2 more sources

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