Results 61 to 70 of about 12,049 (265)

Human polyomaviruses in children undergoing transplantation, United States, 2008-2010 [PDF]

, 2012
Immunocompromised patients are at risk for disease caused by infection by some polyomaviruses. To define the prevalence of polyomaviruses in children undergoing transplantation, we collected samples from a longitudinal cohort and tested for the 9 known ...
Bauer, Irma, Canter, Charles, Hmiel, Paul, Holtz, Lori R, Lassa-Claxton, Sherry, Le, Binh-minh, Shenoy, Shalini, Shepherd, Ross, Siebrasse, Erica A, Sweet, Stuart, Turmelle, Yumirle, Wang, David   +11 more
core   +2 more sources

BK Polyomavirus-Induced Nephropathy in Native Kidney

Cureus, 2023
BK polyomavirus has been well-studied as an opportunistic infection in immunocompromised kidney transplant patients. In the majority of the population, BK polyomavirus establishes a lifelong infection in renal tubular and uroepithelial cells; however, in an immunocompromised state, the virus can reactivate and can lead to BK polyomavirus-associated ...
Munjal, Ripudaman S, Munjal, Jaskaran, Gandhi, Pulkit, Gupta, Nikhil   +3 more
openaire   +2 more sources

Taking the Scenic Route: Polyomaviruses Utilize Multiple Pathways to Reach the Same Destination

Viruses, 2020
Members of the Polyomaviridae family differ in their host range, pathogenesis, and disease severity. To date, some of the most studied polyomaviruses include human JC, BK, and Merkel cell polyomavirus and non-human subspecies murine and simian virus 40 ...
Colleen L. Mayberry, Melissa S. Maginnis
doaj   +1 more source

Evaluation of polyomavirus BK reactivation in lupus patients who underwent kidney transplantation

Microbiologia Medica, 2012
Background. A pathogenic role for polyomavirus BK in systemic lupus erythematosus (SLE) has been proposed, however no study evaluated the occurrence of BK replication in renal transplant recipients according to the underlying disease leading to ...
Cristina Costa, Giovanni Antonio Touscoz, Francesca Sidoti, Franca Sinesi, Daniela Re, Cinzia Balloco, Elsa Piasentin Alessio, Maria Messina, Giuseppe Paolo Segoloni, Rossana Cavallo   +9 more
doaj   +1 more source

The DNA damage response promotes Polyomavirus JC infection by nucleus to cytoplasm NF-Kappa B activation. [PDF]

, 2017
Background: Infection of glial cells by human neurotropic polyomavirus JC (JCV), the causative agent of the CNS demyelinating disease progressive multifocal leukoencephalopathy (PML), rapidly inflicts damage to cellular DNA.
Bellizzi, Anna, Ibba, Gabriele, Palamara, Anna T., Pietropaolo, Valeria, White, Martyn K., Wollebo, Hassen, Wollebo|   +6 more
core   +1 more source

Exposing the Molecular Machinery of BK Polyomavirus [PDF]

Structure, 2016
BK polyomavirus (BKV) is an opportunistic pathogen that poses a serious threat to organ transplant recipients. In this issue of Structure, Hurdiss and colleagues' (Hurdiss et al., 2016) beautiful new high-resolution cryo-EM reconstruction of BKV provides a structural roadmap for the ongoing development of therapeutic antibodies and vaccines targeting ...
openaire   +2 more sources

Identification of the novel KI polyomavirus in paranasal and lung tissues [PDF]

, 2009
KI is a novel polyomavirus identified in the respiratory secretions of children with acute respiratory symptoms. Whether this reflects a causal role of the virus in the human respiratory disease remains to be established.
Aquaro, S, Babakir-Mina, M, Ciccozzi, M, Campitelli, L, Ciotti, M, Lo Coco, A, Perno, CF   +5 more
core   +1 more source

From Data to Decisions: How Machine Learning and Generative Artificial Intelligence Are Redefining Precision Medicine in Kidney Transplantation

Organ Medicine, EarlyView.
This review evaluates how machine learning, multimodal integration, and generative AI optimize kidney transplant outcomes. These tools enable superior prediction and personalized therapy but face hurdles in data volume, generalizability, and ethics. Future clinical adoption depends on continued innovation and multidisciplinary collaboration to overcome
Maoxin Liao, Cheng Yang
wiley   +1 more source

BK viremia in critically ill surgical patients with hemorrhagic or septic shock [PDF]

, 2012
Background Infections with polyomavirus BK virus (BKV) are a common cause of renal dysfunction after renal transplantation and may also be harmful in surgical patients with shock.
Benedikt Weissbrich, Elisabeth Schneider, Manfred Weiss, Maximilian Nass, Moritz Huber   +4 more
core   +2 more sources

Paediatric renal transplantation: Paediatric surgeons' perspective

Surgical Practice, EarlyView.
Abstract Renal transplantation is the most effective treatment for paediatric end‐stage renal disease (ESRD), offering advantages in survival, growth and neurocognitive development that surpass other renal replacement therapies (RRT). The paediatric setting, however, introduces distinct complexities that distinguish it from adult practice.
Adrian Chi‐heng Fung, Mary Kim Elizabeth Tan Cudia, Ivy Hau‐yee Chan, Kenneth Kak‐yuen Wong   +3 more
wiley   +1 more source