Results 71 to 80 of about 12,049 (265)

A highly potent human antibody neutralizing all serotypes of BK polyomavirus.

PLoS Pathogens
BK polyomavirus infection poses a significant risk to kidney transplant recipients. Reactivation of dormant virus in the transplanted kidney, triggered by immunosuppression, can lead to BK polyomavirus-associated nephropathy in up to 10% of transplants ...
Marcel Weber, Simone Schmitt, Barbara Eicher, Jemima Seidenberg, Justina Rutkauskaite, Benedikt Stöckli, Catherine Townsend, Uyen Huynh-Do, Thomas Schachtner, Serena Delbue, Armin Mäder, Christoph Esslinger, Matthias Hillenbrand   +12 more
doaj   +1 more source

Absence of DNA viruses in ameloblastomas

European Journal of Oral Sciences, EarlyView.
Abstract Ameloblastomas (ABs) are rare odontogenic benign tumors. Although studies of the molecular pathogenesis have revealed the presence of mutations and altered gene expression, the etiology is unresolved. Viruses cause 10%–15 % of cancers, but their potential role within benign tumors is less studied.
Maria K. Jauhiainen, Jetta Kelppe, Maria Söderlund‐Venermo, Antti A. Mäkitie, Saku T. Sinkkonen, Jaana Hagström   +5 more
wiley   +1 more source

First confirmed case of native Polyomavirus BK nephropathy in a liver transplant recipient seven years post-transplant

Annals of Hepatology, 2015
Renal dysfunction frequently occurs in liver transplant recipients and is associated with increased morbidity and mortality. BK virus is a human polyoma virus that reactivates during immunocompromised states and is a known cause of renal allograft ...
Yangmin Zeng, Alex Magil, Trana Hussaini, C. Kit Yeung, Siegfried R. Erb, Vladimir Marquez-Alazagara, Eric M. Yoshida, MD, MHSc, FRCP(C), FACP, FACG, FCAHS, FAASLD   +6 more
doaj   +1 more source

Review on the role of the human Polyomavirus JC in the development of tumors [PDF]

, 2017
Almost one fifth of human cancers worldwide are associated with infectious agents, either bacteria or viruses, and this makes the possible association between infections and tumors a relevant research issue.
Manola Comar, Pasquale Ferrante, Serena Delbue   +2 more
core   +1 more source

High Incidence and Early Onset of Urinary Tract Cancers in Patients with BK Polyomavirus Associated Nephropathy

Viruses, 2021
Over-immunosuppressed kidney transplant recipients are susceptible to malignancies and BK polyomavirus (BKPyV)-associated nephropathy (BKPyVAN). This study aimed to verify the association between BKPyV infection and urinary tract cancers (UTC).
Yi-Jung Li, Hsin-Hsu Wu, Cheng-Hsu Chen, Hsu-Han Wang, Yang-Jen Chiang, Hsiang-Hao Hsu, See-Tong Pang, Robert Y. L. Wang, Ya-Chung Tian   +8 more
doaj   +1 more source

BK virus infection, replication, and diseases in pediatric kidney transplantation [PDF]

, 2018
Polyomavirus-associated nephropathy is diagnosed in 2-8% of pediatric renal transplants and often precedes renal allograft dysfunction. Without intervention, however, significant graft dysfunction is observed in more than 50% of cases, although ...
Acott, Philip, Hirsch, Hans
core  

Antiviral regulator TRIM25 as a prognostic marker of better survival in Merkel cell carcinoma: Association with MCPyV status

International Journal of Cancer, Volume 158, Issue 12, Page 3268-3278, 15 June 2026.
What's new? TRIM25 is known for its role in antiviral immunity and association with poor prognosis in various cancers. This study reveals an association between high TRIM25 expression and Merkel cell polyomavirus positivity in Merkel cell carcinoma.
Klaus W. Fagerstedt, Sami Kilpinen, Johanna Arola, Benjamin Z. Sundqvist, Tom Böhling, Leif C. Andersson, Harri Sihto   +6 more
wiley   +1 more source

Nonclassical MHC‐I Molecules: Emerging Therapeutic Targets in Next‐Generation Immunotherapy

MedComm, Volume 7, Issue 5, May 2026.
Immunotherapies dependent on classical MHC‐I molecules face significant challenges, including extreme polymorphism and frequent downregulation in pathological conditions. This review discusses how nonclassical MHC‐I molecules (HLA‐E, HLA‐F, HLA‐G, CD1, MR1) may potentially circumvent these limitations through restricted genetic diversity, stable ...
Wanlin He, Andrew J. McMichael
wiley   +1 more source

Conversion from mycophenolate mofetil to mizoribine in the early stages of BK polyomavirus infection could improve kidney allograft prognosis: a single-center study from China

BMC Nephrology, 2021
Background Some studies have suggested mizoribine (MZR) could inhibit the replication of BK polyomavirus (BKPyV). The purpose of this study was to explore whether conversion from mycophenolate mofetil (MMF) to MZR in the early stages of BKPyV infection ...
Ping Li, Dongrui Cheng, Jiqiu Wen, Xuefeng Ni, Kenan Xie, Xue Li, Jinsong Chen   +6 more
doaj   +1 more source

BK Polyomavirus in Renal Transplantation [PDF]

General Medicine: Open Access, 2014
BK virus is a human polyomavirus that rarely causes disease, except in immune-compromised patients. Evidence of prior BK Virus (BKV) infection is highly prevalent in the general population, and although it rarely causes significant morbidity at primary infection, reactivation of BKV after kidney transplantation is recognized as a cause of BKV ...
openaire   +1 more source