Results 51 to 60 of about 12,049 (265)

Comparison of two RT-qPCR methods targeting BK polyomavirus microRNAs in kidney transplant recipients

open access: yesFrontiers in Medicine, 2023
BackgroundBK polyomavirus replication leads to progressive tubulointerstitial nephritis and ureteral stenosis, with a considerable risk of subsequent graft failure in kidney transplant recipients. Since specific antiviral therapies are lacking, new tools
Kenza Zoubir   +14 more
doaj   +1 more source

BK polyomavirus—pathogen, paradigm and puzzle

open access: yesNephrology Dialysis Transplantation, 2019
AbstractBK virus is a polyomavirus with seroprevalence rates of 80% in adults. Infection is usually acquired during childhood, and the virus is benign or pathologic depending on immune status. The virus reactivates in immunodeficiency states, mostly among transplant (either kidney or bone marrow) recipients.
Suman Krishna Kotla   +3 more
openaire   +2 more sources

BK polyomavirus: latency, reactivation, diseases and tumorigenesis

open access: yesFrontiers in Cellular and Infection Microbiology, 2023
The identification of the first human polyomavirus BK (BKV) has been over half century, The previous epidemiological and phylogenetic studies suggest that BKV prevailed and co-evolved with humans, leading to high seroprevalence all over the world. In general, BKV stays latent and symptomless reactivation in healthy individuals.
Xianfeng Zhou   +4 more
openaire   +3 more sources

Fluoroquinolone prophylaxis in preventing BK polyomavirus infection after renal transplant: A systematic review and meta-analysis

open access: yesKaohsiung Journal of Medical Sciences, 2016
Previous studies regarding the prevention of BK viremia following renal transplantation with fluoroquinolone have yielded conflicting results. The purpose of this systematic review was to examine the evidence regarding the efficacy of fluoroquinolone in ...
Tu-Run Song   +6 more
doaj   +1 more source

Analysis of hemorrhagic cystitis and BK viremia in children after hematopoietic stem cell transplantation

open access: yesIndian Journal of Transplantation, 2022
Purpose: Hemorrhagic cystitis (HC) which occurs in 9%–31% of recipients after hematopoietic stem cell transplantation (HSCT) is an important cause of morbidity and mortality.
Ayça Koca Yozgat   +7 more
doaj   +1 more source

BK Virus in Cancer Development

open access: yesCurrent Issues in Pharmacy and Medical Sciences, 2018
Polyomavirus (PyV) was discovered by accident in 1950 in the course of describing an infectious factor causing multiple tumours in rodents. The term is derived from two Greek words: poly (many) and oma (tumour).
Pasternak Justyna   +2 more
doaj   +1 more source

Detection of Bk Polyomavirus Antigen in Patients with Acute Lymphoblastic Leukemia

open access: yesDiyala Journal of Medicine, 2023
Background: BK polyomavirus  that is acquired in early childhood as BKPyV is near ubiquitous in adults with a seroprevalence of >80%, it has been found as the main cause of hemorrhagic cystitis in hematopoietic stem cell transplantation patients, due to
Safa H Ali ,   +3 more
doaj   +1 more source

Detection and differentiation of human polyomaviruses JC and BK by LightCycler PCR [PDF]

open access: yes, 2001
Human polyomaviruses JC and BK may cause several clinical manifestations in immunocompromised hosts, including progressive multifocal leukoencephalopathy and hemorrhagic cystitis.
Whiley, David M.   +2 more
core   +1 more source

Natalizumab affects T-cell phenotype in multiple sclerosis: implications for JCV reactivation [PDF]

open access: yes, 2016
The anti-CD49d monoclonal antibody natalizumab is currently an effective therapy against the relapsing-remitting form of multiple sclerosis (RRMS). Natalizumab therapeutic efficacy is limited by the reactivation of the John Cunningham polyomavirus (JCV ...
A Bellizzi   +51 more
core   +8 more sources

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