Results 51 to 60 of about 80,646 (211)

BK polyomavirus: latency, reactivation, diseases and tumorigenesis

Frontiers in Cellular and Infection Microbiology, 2023
The identification of the first human polyomavirus BK (BKV) has been over half century, The previous epidemiological and phylogenetic studies suggest that BKV prevailed and co-evolved with humans, leading to high seroprevalence all over the world. In general, BKV stays latent and symptomless reactivation in healthy individuals.
Xianfeng Zhou, Xianfeng Zhou, Xianfeng Zhou, Chunlong Zhu, Hui Li   +4 more
openaire   +3 more sources

Evaluation of polyomavirus BK reactivation in lupus patients who underwent kidney transplantation

Microbiologia Medica, 2012
Background. A pathogenic role for polyomavirus BK in systemic lupus erythematosus (SLE) has been proposed, however no study evaluated the occurrence of BK replication in renal transplant recipients according to the underlying disease leading to ...
Cristina Costa, Giovanni Antonio Touscoz, Francesca Sidoti, Franca Sinesi, Daniela Re, Cinzia Balloco, Elsa Piasentin Alessio, Maria Messina, Giuseppe Paolo Segoloni, Rossana Cavallo   +9 more
doaj   +1 more source

Taking the Scenic Route: Polyomaviruses Utilize Multiple Pathways to Reach the Same Destination

Viruses, 2020
Members of the Polyomaviridae family differ in their host range, pathogenesis, and disease severity. To date, some of the most studied polyomaviruses include human JC, BK, and Merkel cell polyomavirus and non-human subspecies murine and simian virus 40 ...
Colleen L. Mayberry, Melissa S. Maginnis
doaj   +1 more source

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source

Exposing the Molecular Machinery of BK Polyomavirus [PDF]

Structure, 2016
BK polyomavirus (BKV) is an opportunistic pathogen that poses a serious threat to organ transplant recipients. In this issue of Structure, Hurdiss and colleagues' (Hurdiss et al., 2016) beautiful new high-resolution cryo-EM reconstruction of BKV provides a structural roadmap for the ongoing development of therapeutic antibodies and vaccines targeting ...
openaire   +2 more sources

Association Between the Time of Day of Post‐Transplant Cyclophosphamide Administration and Haemorrhagic Cystitis After Allogeneic Haematopoietic Stem Cell Transplantation

European Journal of Haematology, EarlyView.
ABSTRACT Objective To evaluate the impact of the time‐of‐day (daytime vs. nighttime) of the infusion of post‐transplantation cyclophosphamide (PTCy) on the occurrence of haemorrhagic cystitis (HC) in adult patients undergoing allogeneic haematopoietic stem cell transplantation (allo‐HSCT).
Maria‐Estela Moreno‐Martinez, Mireia Riba, Albert Esquirol, Irene García‐Cadenas, Clara Vila‐Gallego, Jose Manuel Portos, Ignasi Gich, Annalisa Paviglianiti, Sara Redondo, Javier Briones, Anna Feliu, Rodrigo Martino   +11 more
wiley   +1 more source

The lymphocyte function of allogeneic peripheral blood stem cell grafts is associated with relapse and cytomegalovirus reactivation

Transfusion, EarlyView.
Abstract Background Allogeneic hematopoietic stem cell transplantation (HSCT) is a treatment primarily for hematological malignancies. Infections, relapse, and graft versus host disease (GvHD) are some of the most common adverse events following HSCT. We aimed to evaluate whether the lymphocyte function of the stem cell graft was associated with these ...
Anna Söderström, Tengyu Wang, Johan Törlén, Hannes Lindahl, Davide Valentini, Stephan Mielke, Klara Asplund Högelin, Rebecca Axelsson Robertson, Michael Uhlin   +8 more
wiley   +1 more source

Increased Prevalence of Polyomavirus Bk Viruria That Correlates with Thrombocytopenia in Patients with Systemic Lupus Erythematosus on Intensive Immunosuppressive Therapy

, 2010
The prevalence of polyomavirus BK (BKV) reactivation is high in patients with systemic lupus erythematosus (SLE) on long -term immunosuppressants compared to normal population. However, only a few studies are available for the possible correlation of BKV
LU, MING-CHI;YU, CHIA-LI;YIN, WEN-YAO;TUNG, CHIEN-HSUEH;HUANG, KUANG-YUNG;LIU, SU-QIN;LAI, NING-SHENG, 呂明錡;余家利;尹文耀;童建學;黃光永;劉素勤;賴寧生   +1 more
core   +1 more source

First confirmed case of native Polyomavirus BK nephropathy in a liver transplant recipient seven years post-transplant

Annals of Hepatology, 2015
Renal dysfunction frequently occurs in liver transplant recipients and is associated with increased morbidity and mortality. BK virus is a human polyoma virus that reactivates during immunocompromised states and is a known cause of renal allograft ...
Yangmin Zeng, Alex Magil, Trana Hussaini, C. Kit Yeung, Siegfried R. Erb, Vladimir Marquez-Alazagara, Eric M. Yoshida, MD, MHSc, FRCP(C), FACP, FACG, FCAHS, FAASLD   +6 more
doaj   +1 more source

Polyomavirus Drives Cerebellar Lesions in AIDS Monkeys With Ataxia

MedComm, Volume 7, Issue 11, November 2026.
Chronic SIV‐infected macaques with ataxia develop severe cerebellar lesions driven by simian polyomavirus 40 (SV40) infection. SV40 preferentially infects cerebellar granule cells, inducing pyroptosis and an aberrant proliferative state. Pyroptotic neuronal injury promotes microglial recruitment and activation, amplifying local neuroinflammation and ...
Tian‐Zhang Song, Li‐Rong Zhang, Yun‐Mei Wang, Yan Hu, Qing Li, Ren‐Rong Tian, Liu‐Meng Yang, Si‐Dong Xiong, Dong‐Dong Wu, Yong‐Tang Zheng   +9 more
wiley   +1 more source