Results 81 to 90 of about 6,754 (176)

The case for BK polyomavirus as a cause of bladder cancer

Current Opinion in Virology, 2019
In 2014, the International Agency for Research on Cancer judged Merkel cell polyomavirus (MCPyV) to be a probable human carcinogen. BK polyomavirus (BKPyV, a distant cousin of MCPyV) was ruled a possible carcinogen. In this review, we argue that it has recently become reasonable to view both of these viruses as known human carcinogens.
Gabriel J, Starrett, Christopher B, Buck
openaire   +3 more sources

A Retrograde Trafficking Inhibitor of Ricin and Shiga-Like Toxins Inhibits Infection of Cells by Human and Monkey Polyomaviruses

mBio, 2013
Polyomaviruses are ubiquitous pathogens that cause severe disease in immunocompromised individuals. JC polyomavirus (JCPyV) is the causative agent of the fatal demyelinating disease progressive multifocal leukoencephalopathy (PML), whereas BK ...
Christian D. S. Nelson, Dan W. Carney, Aaron Derdowski, Alex Lipovsky, Gretchen V. Gee, Bethany O’Hara, Paul Williard, Daniel DiMaio, Jason K. Sello, Walter J. Atwood   +9 more
doaj   +1 more source

BK polyomavirus infection: more than 50 years and still a threat to kidney transplant recipients

Frontiers in Transplantation
BK polyomavirus (BKPyV) is a ubiquitous human polyomavirus and a major infection after kidney transplantation, primarily due to immunosuppression. BKPyV reactivation can manifest as viruria in 30%–40%, viremia in 10%–20%, and BK polyomavirus-associated ...
Sandesh Parajuli, Fahad Aziz, Weixiong Zhong, Arjang Djamali   +3 more
doaj   +1 more source

Polyomavirus specific cellular immunity: from BK-virus-specific cellular immunity to BK-virus-associated nephropathy ?

Frontiers in Immunology, 2015
In renal transplantation, BK-virus-associated nephropathy has emerged as a major complication, with a prevalence of 5–10% and graft loss in >50% of cases. BK-virus is a member of the Polyomavirus family and rarely induces apparent clinical disease in the
manon edekeyser, helene efrancois, severine ebeaudreuil, Antoine eDurrbach   +3 more
doaj   +1 more source

An unusually high substitution rate in transplant-associated BK polyomavirus in vivo is further concentrated in HLA-C-bound viral peptides.

PLoS Pathogens, 2018
Infection with human BK polyomavirus, a small double-stranded DNA virus, potentially results in severe complications in immunocompromised patients. Here, we describe the in vivo variability and evolution of the BK polyomavirus by deep sequencing.
Pilar Domingo-Calap, Benjamin Schubert, Mélanie Joly, Morgane Solis, Meiggie Untrau, Raphael Carapito, Philippe Georgel, Sophie Caillard, Samira Fafi-Kremer, Nicodème Paul, Oliver Kohlbacher, Fernando González-Candelas, Seiamak Bahram   +12 more
doaj   +1 more source

Renal Allograft Biopsies with Polyomavirus BK Nephropathy: Turin Transplant Center, 2015-19. [PDF]

Viruses, 2020
Zanotto E, Allesina A, Barreca A, Sidoti F, Gallo E, Bottino P, Iannaccone M, Bianco G, Biancone L, Cavallo R, Costa C.   +10 more
europepmc   +1 more source

Development of a Nucleic Acid Lateral Flow Immunoassay for the Detection of Human Polyomavirus BK. [PDF]

Diagnostics (Basel), 2020
Huang YH, Yu KY, Huang SP, Chuang HW, Lin WZ, Cherng JH, Hung YW, Yeh MK, Hong PD, Liu CC.   +9 more
europepmc   +1 more source

Clinical Efficacy of Intravenous Immunoglobulin for BK Polyomavirus-Associated Nephropathy After Living Kidney Transplantation

Therapeutics and Clinical Risk Management, 2020
Soichi Matsumura,1 Taigo Kato,1,2 Ayumu Taniguchi,1 Masataka Kawamura,1 Shigeaki Nakazawa,1 Tomoko Namba-Hamano,3 Toyofumi Abe,1 Norio Nonomura,1 Ryoichi Imamura1 1Department of Urology, Osaka University Graduate School of Medicine, Osaka 565-0871, Japan;
Matsumura S, Kato T, Taniguchi A, Kawamura M, Nakazawa S, Namba-Hamano T, Abe T, Nonomura N, Imamura R   +8 more
doaj  

Experience of BK Virus in Allogenic and Autologous Bone Marrow Transplantation:

Mediterranean Journal of Hematology and Infectious Diseases, 2014
The BK virus is a member of the polyomavirus family. When the immune system is compromised, as in patients undergoing chemotherapy after hematopoietic stem cell and solid organ transplantation, the virus is reactivated leading to haemorrhagic cystitis ...
Ilhami BERBER, Mehmet Ali ERKURT, Emin KAYA, Irfan KUKU, Mustafa KOROGLU, Ilknur NIZAM   +5 more
doaj  

Allogeneic CD4 T Cells Sustain Effective BK Polyomavirus-Specific CD8 T Cell Response in Kidney Transplant Recipients

Kidney International Reports
Introduction: BK polyomavirus-associated nephropathy (BKPyVAN) is a significant complication in kidney transplant recipients (KTRs), associated with a higher level of plasmatic BK polyomavirus (BKPyV) replication and leading to poor graft survival ...
Manon Dekeyser, Marie-Ghislaine de Goër de Herve, Houria Hendel-Chavez, Romain Lhotte, Ivan Scriabine, Karen Bargiel, Emmanuelle Boutin, Florence Herr, Jean-Luc Taupin, Yassine Taoufik, Antoine Durrbach   +10 more
doaj   +1 more source