Results 21 to 30 of about 3,251 (110)

The Mystery of Exosomes in Gestational Diabetes Mellitus

Oxidative Medicine and Cellular Longevity, Volume 2022, Issue 1, 2022., 2022
Gestational diabetes mellitus (GDM) is one of the common pregnancy complications, which increases the risk of short‐term and long‐term adverse consequences in both the mother and offspring. However, the pathophysiological mechanism of GDM is still poorly understood.
Tong Chen, Dan Liu, Demetrios Kouretas
wiley   +1 more source

Dissecting the phenotypic components and genetic architecture of maize stem vascular bundles using high‐throughput phenotypic analysis

Plant Biotechnology Journal, Volume 19, Issue 1, Page 35-50, January 2021., 2021
Summary High‐throughput phenotyping is increasingly becoming an important tool for rapid advancement of genetic gain in breeding programmes. Manual phenotyping of vascular bundles is tedious and time‐consuming, which lags behind the rapid development of functional genomics in maize.
Ying Zhang, Jinglu Wang, Jianjun Du, Yanxin Zhao, Xianju Lu, Weiliang Wen, Shenghao Gu, Jiangchuan Fan, Chuanyu Wang, Sheng Wu, Yongjian Wang, Shengjin Liao, Chunjiang Zhao, Xinyu Guo   +13 more
wiley   +1 more source

MiR-183-5p-PNPT1 Axis Enhances Cisplatin-induced Apoptosis in Bladder Cancer Cells

Current Medical Science, 2022
It has been reported that intrinsic apoptosis is associated with the progression of bladder cancer (BC). Recent evidence suggests that polyribonucleotide nucleotidyltransferase 1 (PNPT1) is a pivotal mediator involved in RNA decay and cell apoptosis ...
Qing-gang Hu, Zhi Yang, Jia-wei Chen, Gallina Kazobinka, L. Tian, Wen-cheng Li   +5 more
semanticscholar   +1 more source

3′-Terminal 2′-O-methylation of lung cancer miR-21-5p enhances its stability and association with Argonaute 2

Nucleic Acids Research, 2020
Methylation of miRNAs at the 2′-hydroxyl group on the ribose at 3′-end (2′-O-methylation, 2′Ome) is critical for miRNA function in plants and Drosophila. Whether this methylation phenomenon exists for mammalian miRNA remains unknown.
Hongwei Liang, Zichen Jiao, Weiwei Rong, Shuang Qu, Zhicong Liao, Xinlei Sun, Yao Wei, Quan Zhao, Jun Wang, Yuan Liu, Xi Chen, Tao Wang, Chen-Yu Zhang, Ke Zen   +13 more
semanticscholar   +1 more source

Prevention of dsRNA‐induced interferon signaling by AGO1x is linked to breast cancer cell proliferation

EMBO Journal, 2020
Translational readthrough, i.e., elongation of polypeptide chains beyond the stop codon, was initially reported for viral RNA, but later found also on eukaryotic transcripts, resulting in proteome diversification and protein‐level modulation.
Souvik Ghosh, Joao C. Guimaraes, Manuela Lanzafame, A. Schmidt, Afzal P. Syed, Beatrice Dimitriades, Anastasiya Börsch, Shreemoyee Ghosh, Nitish Mittal, Thomas Montavon, A. L. Correia, Johannes Danner, G. Meister, L. Terracciano, S. Pfeffer, S. Piscuoglio, M. Zavolan   +16 more
semanticscholar   +1 more source

RNA binding protein FXR1-miR301a-3p axis contributes to p21WAF1 degradation in oral cancer

PLoS Genetics, 2020
RNA‐binding proteins (RBPs) associate with primary, precursor, and mature microRNAs (miRNAs), which in turn control mature miRNA levels, and post‐transcriptional gene regulation (PTR).
Mrinmoyee Majumder, Viswanathan Palanisamy   +1 more
semanticscholar   +1 more source

Insights into the genome structure of four acetogenic bacteria with specific reference to the Wood–Ljungdahl pathway

MicrobiologyOpen, Volume 8, Issue 12, December 2019., 2019
Acetogenic bacteria are able to convert one‐carbon substrates into acetate through the Wood‐Ljungdahl (WL) pathway. We report a comparative genomic analysis of four acetogenic species with a focus on the genes encoding enzymes of the WL pathway. We found variations in the organization of WL pathway gene clusters and an expansion of protein orthologues.
Alfonso Esposito, Sabrina Tamburini, Luca Triboli, Luca Ambrosino, Maria Luisa Chiusano, Olivier Jousson   +5 more
wiley   +1 more source

Adaptation of the Alphaproteobacterium Rhodobacter sphaeroides to stationary phase

Environmental Microbiology, Volume 21, Issue 11, Page 4425-4445, November 2019., 2019
Summary Exhaustion of nutritional resources stimulates bacterial populations to adapt their growth behaviour. General mechanisms are known to facilitate this adaptation by sensing the environmental change and coordinating gene expression. However, the existence of such mechanisms among the Alphaproteobacteria remains unclear.
Matthew McIntosh, Katrin Eisenhardt, Bernhard Remes, Anne Konzer, Gabriele Klug   +4 more
wiley   +1 more source

Integrating GWAS and gene expression data for functional characterization of resistance to white mould in soya bean

Plant Biotechnology Journal, Volume 16, Issue 11, Page 1825-1835, November 2018., 2018
Summary White mould of soya bean, caused by Sclerotinia sclerotiorum (Lib.) de Bary, is a necrotrophic fungus capable of infecting a wide range of plants. To dissect the genetic architecture of resistance to white mould, a high‐density customized single nucleotide polymorphism (SNP) array (52 041 SNPs) was used to genotype two soya bean diversity ...
Zixiang Wen, Ruijuan Tan, Shichen Zhang, Paul J. Collins, Jiazheng Yuan, Wenyan Du, Cuihua Gu, Shujun Ou, Qijian Song, Yong‐Qiang Charles An, John F. Boyse, Martin I. Chilvers, Dechun Wang   +12 more
wiley   +1 more source

Transcriptome atlas of Striga germination: Implications for managing an intractable parasitic plant

PLANTS, PEOPLE, PLANET, Volume 7, Issue 2, Page 396-410, March 2025.
Witchweeds, parasitic plants of the genus Striga, are nicknamed “cereal killers” because of their devastating destruction of Africa's most staple cereals, including maize, sorghum, millets, and upland rice. The parasite relies on biomolecules emitted from the host roots to germinate and therefore initiate its infectious lifecycle.
Gilles Irafasha, Sylvia Mutinda, Fredrick Mobegi, Brett Hale, George Omwenga, Asela J. Wijeratne, Susann Wicke, Emily S. Bellis, Steven Runo   +8 more
wiley   +1 more source