Results 21 to 30 of about 3,888 (165)

Mitochondrial RNA processing defect caused by a SUPV3L1 mutation in two siblings with a novel neurodegenerative syndrome

Journal of Inherited Metabolic Disease, Volume 45, Issue 2, Page 292-307, March 2022., 2022
Abstract SUPV3L1 encodes a helicase that is mainly localized in the mitochondria. It has been shown in vitro to possess both double‐stranded RNA and DNA unwinding activity that is ATP‐dependent. Here we report the first two patients for this gene who presented with a homozygous preliminary stop codon resulting in a C‐terminal truncation of the SUPV3L1 ...
Selma L. van Esveld, Richard J. Rodenburg, Fathiya Al‐Murshedi, Eiman Al‐Ajmi, Sana Al‐Zuhaibi, Martijn A. Huynen, Johannes N. Spelbrink   +6 more
wiley   +1 more source

Comparative genomics provides structural and functional insights into Bacteroides RNA biology

Molecular Microbiology, Volume 117, Issue 1, Page 67-85, January 2022., 2022
Most of our knowledge of bacterial regulatory RNAs and their associated proteins stems from model organisms such as Escherichia coli and Salmonella enterica. In contrast, the RNA biology of Bacteroides spp.—an important component of the human gut microbiota—is significantly understudied.
Gianluca Prezza, Daniel Ryan, Gohar Mädler, Sarah Reichardt, Lars Barquist, Alexander J. Westermann   +5 more
wiley   +1 more source

The Mystery of Exosomes in Gestational Diabetes Mellitus

Oxidative Medicine and Cellular Longevity, Volume 2022, Issue 1, 2022., 2022
Gestational diabetes mellitus (GDM) is one of the common pregnancy complications, which increases the risk of short‐term and long‐term adverse consequences in both the mother and offspring. However, the pathophysiological mechanism of GDM is still poorly understood.
Tong Chen, Dan Liu, Demetrios Kouretas
wiley   +1 more source

Systematic identification of gene families for use as markers for phylogenetic and phylogeny- driven ecological studies of bacteria and archaea and their major subgroups [PDF]

, 2013
With the astonishing rate that the genomic and metagenomic sequence data sets are accumulating, there are many reasons to constrain the data analyses.
Eisen, Jonathan A., Jospin, Guillaume, Wu, Dongying   +2 more
core   +7 more sources

Dissecting the phenotypic components and genetic architecture of maize stem vascular bundles using high‐throughput phenotypic analysis

Plant Biotechnology Journal, Volume 19, Issue 1, Page 35-50, January 2021., 2021
Summary High‐throughput phenotyping is increasingly becoming an important tool for rapid advancement of genetic gain in breeding programmes. Manual phenotyping of vascular bundles is tedious and time‐consuming, which lags behind the rapid development of functional genomics in maize.
Ying Zhang, Jinglu Wang, Jianjun Du, Yanxin Zhao, Xianju Lu, Weiliang Wen, Shenghao Gu, Jiangchuan Fan, Chuanyu Wang, Sheng Wu, Yongjian Wang, Shengjin Liao, Chunjiang Zhao, Xinyu Guo   +13 more
wiley   +1 more source

Redox stress defines the small artery vasculopathy of hypertension: how do we bridge the bench-to-bedside gap? [PDF]

, 2017
Although convincing experimental evidence demonstrates the importance of vascular reactive oxygen and nitrogen species (RONS), oxidative stress, and perturbed redox signaling as causative processes in the vasculopathy of hypertension, this has not ...
Liang, Mingyu, Montezano, Augusto C., Rios, Francisco, Touyz, Rhian M., Widlansky, Michael E.   +4 more
core   +1 more source

Multilocus Genotyping Reveals New Molecular Markers for Differentiating Distinct Genetic Lineages among “Candidatus Phytoplasma Solani” Strains Associated with Grapevine Bois Noir [PDF]

, 2020
none18openPassera, Alessandro; Zhao, Yan; Murolo, Sergio; Pierro, Roberto; Arsov, Emilija; Mori, Nicola; Moussa, Abdelhameed; Silletti, Maria R.; Casati, Paola; Panattoni, Alessandra; Wei, Wei; Mitrev, Sasa; Materazzi, Alberto; Luvisi, Andrea; Romanazzi,
Arsov E., Bianco P. A., Casati P., Davis R. E., Luvisi A., Materazzi A., Mitrev S., Mori N., Moussa A., Murolo S., Panattoni A., Passera A., Pierro R., Quaglino F., Romanazzi G., Silletti M. R., Wei W., Zhao Y.   +17 more
core   +4 more sources

Modulation of Neurogenesis through the Promotion of Energy Production Activity Is behind the Antidepressant-Like Effect of Colonial Green Alga, Botryococcus braunii [PDF]

, 2017
Algae have been recognized as important resources providing functional components due to their capacity to exert beneficial effects on health. Therefore, there is increasing interest in investigating the biological activity of algae.
Demura Mikihide, Isoda Hiroko, Othman Mahmoud B., Sasaki Kazunori, Watanabe Makoto, 佐々木 一憲, 礒田 博子   +6 more
core   +1 more source

3′-Terminal 2′-O-methylation of lung cancer miR-21-5p enhances its stability and association with Argonaute 2

Nucleic Acids Research, 2020
Methylation of miRNAs at the 2′-hydroxyl group on the ribose at 3′-end (2′-O-methylation, 2′Ome) is critical for miRNA function in plants and Drosophila. Whether this methylation phenomenon exists for mammalian miRNA remains unknown.
Hongwei Liang, Zichen Jiao, Weiwei Rong, Shuang Qu, Zhicong Liao, Xinlei Sun, Yao Wei, Quan Zhao, Jun Wang, Yuan Liu, Xi Chen, Tao Wang, Chen-Yu Zhang, Ke Zen   +13 more
semanticscholar   +1 more source

Transient expression of βC1 protein differentially regulates host genes related to stress response, chloroplast and mitochondrial functions [PDF]

, 2010
Background Geminiviruses are emerging plant pathogens that infect a wide variety of crops including cotton, cassava, vegetables, ornamental plants and cereals.
Amin, Imran, Andleeb, Saiqa, Bashir, Aftab, Briddon, Rob W, Mansoor, Shahid   +4 more
core   +3 more sources