Results 141 to 150 of about 2,499 (191)

Normal phase chiral HPLC of methylphenidate: Comparison of different polysaccharide‐based chiral stationary phases

Chirality, 2001
AbstractA comparison of the enantiomeric resolution of (±)‐threo‐methylphenidate (MPH) (Ritalin®) was achieved on different polysaccharide based chiral stationary phases. The mobile phase used was hexane‐ethanol‐methanol‐trifluoroacetic acid (480:9.75:9.75:0.5, v/v/v/v).
Hassan Y, Aboul-Enein, Imran, Ali
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Enantioseparation of amino acids on a polysaccharide-based chiral stationary phase

Journal of Chromatography A, 2002
Sulfonic acids have been shown to be more effective than the commonly used trifluoroacetic acid (TFA) in the chiral resolution of underivatized aromatic amino acids on an amylosic column. Sulfonic acid additives give a more UV transparent mobile phase, possibly allowing the detection of non-aromatic analytes.
Yun K, Ye, Barbara S, Lord, Li, Yin, Rodger W, Stringham   +3 more
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Chiral Separation of Organic Phosphonate Compounds on Polysaccharide-Based Chiral Stationary Phases

Chromatographia, 2004
Four polysaccharide-based chiral stationary phases have been used to separate the enantiomers of fourteen O,O-dialkyl-1-benzyloxycarbonyl-aminoarylmethyl phosphonates. These polysaccharide-based chiral stationary phases are Chiralpak AD, Chiralpak AS, Chiralcel OG and Chiralcel OJ. The data obtained indicate that the chiral separation ability for these
G. S. Yang, C. Y. Zhan, G. H. Fu, P. Parrilla Vazquez, A. Garrido Frenich, J. L. Martinez Vidal, H. Y. Aboul-Enein   +6 more
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Enantioselective potential of polysaccharide‐based chiral stationary phases in supercritical fluid chromatography

Chirality, 2017
AbstractThe enantioselective potential of two polysaccharide‐based chiral stationary phases for analysis of chiral structurally diverse biologically active compounds was evaluated in supercritical fluid chromatography using a set of 52 analytes.
Gabriela Kucerova, Kveta Kalikova, Eva Tesarova   +2 more
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Chromatographic enantioseparations of binaphthyl compounds on an immobilized polysaccharide-based chiral stationary phase

Journal of Chromatography A, 2008
Seven binaphthyl compounds were enantioseparated by HPLC with an immobilized polysaccharide-based chiral stationary phase, Chiralpak IA. The experiments were performed under normal-phase conditions. Effects of polar modifier and column temperature on the retention time and separation factor were evaluated.
Wen, Weng, Hongxu, Guo, Fengping, Zhan, Hongli, Fang, Qingxiang, Wang, Bixia, Yao, Shunxing, Li   +6 more
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A separation strategy combining three HPLC modes and polysaccharide-based chiral stationary phases

Journal of Pharmaceutical and Biomedical Analysis, 2013
Nine polysaccharide-based chiral stationary phases (CSPs) were used to define a separation strategy that combines normal-phase (NP), reversed-phase (RP) and polar organic solvent chromatography (POSC) modes. After limiting ourselves to two CSPs per mode, in total, five CSPs, Chiralpak AD (NP), Chiralcel OD (RP and POSC), Lux Cellulose-1 (NP), Lux ...
Younes, Ahmed, Ates, Hasret, Mangelings, Debby, Yvan, Vander Heyden   +3 more
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Chiral separation and molecular modeling study of decursinol and its derivatives using polysaccharide-based chiral stationary phases

Journal of Chromatography A, 2023
Plant-based bioactive substances have long been used to treat inflammatory ailments, owing to their low toxicity and cost-effectiveness. To enhance plant treatment by eliminating undesirable isomers, optimizing the chiral separation techniques in pharmaceutical and clinical studies is important.
Bao Tan, Nguyen, Yoon Jung, Choi, Kyeong Ho, Kim, Gyu Yong, Song, Hyung Min, Kim, Jong Seong, Kang   +5 more
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Chiral separability of boron cluster species studied by screening approaches utilizing polysaccharide‐based chiral stationary phases

Biomedical Chromatography, 2014
ABSTRACTIn this study, the screening steps of chiral separation strategies with polysaccharide‐based chiral stationary phases were applied on boron cluster compounds in normal‐phase liquid chromatography (NPLC) and polar organic solvents chromatography (POSC).
Mangelings, Debby, Yvan, Vander Heyden, Vespalec, R.   +2 more
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Enantioseparation of 1-Phenyl-1,2,3,4-tetrahydroisoquinoline on Polysaccharide-Based Chiral Stationary Phases

Chromatographia, 2011
The enantiomers of 1-phenyl-1,2,3,4-tetrahydroisoquinoline have been directly separated on polysaccharide-based chiral stationary phases (CSPs). The normal phase separation of (S)- and (R)-1-phenyl-1,2,3,4-tetrahydroisoquinoline was accomplished by screening of the immobilized Chiralpak IC column with different eluents.
Helena Kažoka, Oksana Rotkaja, Larisa Varačeva   +2 more
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Chiral Separation of Several Pyrethroids on Polysaccharide‐Based Chiral Stationary Phases Under Normal and Reversed Phase Modes

Journal of Liquid Chromatography & Related Technologies, 2004
Abstract The enantiomers of eight pyrethroid insecticides have been separated by three polysaccharide‐based chiral stationary phases (CSP), namely Chiralcel OD‐R, Chiralpak AD, and Chiralcel OJ, both in reversed and normal phase modes. Deltamethrin, fenpropathrin, and lambda‐cyhalothrin could be baseline separated on Chiralcel OD‐R in reversed phase ...
Guo‐Sheng Yang, Piedad Parrilla Vázquez, Antonia Garrido Frenich, Jose L. Martínez Vidal, Hassan Y. Aboul‐Enein   +4 more
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