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Enantiomer separation of fungicidal triazolyl alcohols by normal phase HPLC on polysaccharide-based chiral stationary phases

Chirality, 1999
Three fungicidal triazolyl alcohols (triadimenol, hexaconazole, and cis/trans-1-4-chlorophenyl-2-1H-1,2,4-triazol-1-yl-cycloheptanol) were completely separated into enantiomers by chiral HPLC using polysaccharide-based chiral stationary phases. A better separation was achieved on cellulose and amylose carbamate phases compared with a cellulose ester ...
Torsten Spitzer   +2 more
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CHIRAL RECOGNITION MECHANISM OF b-AMINO ALCOHOLS ON POLYSACCHARIDE-BASED CHIRAL STATIONARY PHASE

2005
The b-amino alcohols are compounds of great interest in synthetic organic chemistry as subunits in many important biologically active natural and synthetic products[1]. Based on their pharmacological action therapeutic activity of these molecules can be divided into three categories: vasoconstrictors, antihypertensive agents and b-blockers [2, 3].
Šporec, Anita   +3 more
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Enantioseparations by High-Performance Liquid Chromatography Using Polysaccharide-Based Chiral Stationary Phases: An Overview

2012
This chapter summarizes the application of polysaccharide-based chiral stationary phases (CSPs) for separation of enantiomers in high-performance liquid chromatography (HPLC). Since this book contains dedicated chapters on enantioseparations using supercritical fluid chromatography (SFC), capillary electrochromatography (CEC), and simulated moving bed (
openaire   +2 more sources

Polysaccharide-Based Chiral Stationary Phases for Enantioseparations by High-Performance Liquid Chromatography: An Overview

2019
This chapter summarizes the application of polysaccharide-based chiral stationary phases (CSPs) for separation of enantiomers in high-performance liquid chromatography (HPLC). Since this book contains dedicated chapters on enantioseparations using supercritical fluid chromatography (SFC), or capillary electrochromatography (CEC), the application of ...
openaire   +2 more sources

Direct HPLC enantioseparation of Cetirizine Hydrochloride on polysaccharide-based chiral stationary phases

2005
Cetirizine hydrochloride is a non-sedating H1-receptor antagonist used in patients whit urticaria and allergic rhinitis. It is frequently administrated as racemate; although recent data demonstrate that the antihistaminergic activity of the racemate is primarily due to the levo-enantiomer, while dextrocetirizine failed to demonstrate any significant ...
RUSTICHELLI, Cecilia   +4 more
openaire   +1 more source

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