Functional Exploration of the Polysaccharide Lyase Family PL6. [PDF]
Alginate, the main cell-wall polysaccharide of brown algae, is composed of two residues: mannuronic acid (M-residues) and, its C5-epimer, guluronic acid (G-residues).
Sophie Mathieu +4 more
doaj +9 more sources
Polysaccharide lyases are the products of various microorganisms, bacteriophage and some eukaryotes. All such enzymes cleave a hexose-1,4-alpha- or beta-uronic acid sequence by beta-elimination. They are in some examples, the only known type of enzymes degrading their polyanionic substrates.
I Sutherland
+6 more sources
A hierarchical classification of polysaccharide lyases for glycogenomics [PDF]
Carbohydrate-active enzymes face huge substrate diversity in a highly selective manner using only a limited number of available folds. They are therefore subjected to multiple divergent and convergent evolutionary events. This and their frequent modularity render their functional annotation in genomes difficult in a number of cases.
Vincent Lombard +5 more
openalex +7 more sources
Substrate recognition and catalysis of polysaccharide lyases [PDF]
Sine Larsen +9 more
openalex +3 more sources
From structure to function: Smlt1473, a pH-dependent polysaccharide lyase [PDF]
Shubhant Pandey +4 more
openalex +3 more sources
Rhamnogalacturonan lyase reveals a unique fold and suggests a common polysaccharide lyase mechanism [PDF]
M.A. McDonough +4 more
openalex +3 more sources
Engineering broad-spectrum digestion of polyuronides from an exolytic polysaccharide lyase [PDF]
Macroalgae represents a promising source of fermentable carbohydrates for use in the production of energy efficient biofuel. The primary carbohydrate in brown algae is the uronic acid-containing alginate, whereas green algae contains a significant amount of glucuronan.
Logan C. MacDonald +2 more
openalex +4 more sources
Alginate is an anionic polysaccharide abundantly present in the cell walls of brown macroalgae. The enzymatic depolymerization is performed solely by alginate lyases (EC 4.2.2.x), categorized as polysaccharide lyases (PLs) belonging to 12 different PL ...
Bo Pilgaard +4 more
doaj +1 more source
The O-specific polysaccharide lyase from the phage LKA1 tailspike reduces Pseudomonas virulence [PDF]
AbstractPseudomonas phage LKA1 of the subfamily Autographivirinae encodes a tailspike protein (LKA1gp49) which binds and cleaves B-band LPS (O-specific antigen, OSA) of Pseudomonas aeruginosa PAO1. The crystal structure of LKA1gp49 catalytic domain consists of a beta-helix, an insertion domain and a C-terminal discoidin-like domain.
Tomasz Olszak +17 more
openalex +4 more sources
Applying a polysaccharide lyase from <i>Stenotrophomonas maltophilia</i> to disrupt alginate exopolysaccharide produced by <i>Pseudomonas aeruginosa</i> clinical isolates. [PDF]
Felton SM +10 more
europepmc +2 more sources

