Insights into putative alginate lyases from epipelagic and mesopelagic communities of the global ocean. [PDF]
Sci RepAlginate lyases and oligoalginate lyases catalyze the cleavage of the glycosidic bonds of alginate, an acidic polysaccharide synthesized by brown algae and other organisms.
Lozada M, Dionisi HM.
europepmc +2 more sources
Frontiers in Bioengineering and Biotechnology, 2020 Fungal genomes often contain several copies of genes that encode carbohydrate active enzymes having similar activity. The copies usually have slight sequence variability, and it has been suggested that the multigenecity represents distinct reaction ...
Birgitte Zeuner +5 more
doaj +2 more sources
Crystal structure and catalytic mechanism of PL35 family glycosaminoglycan lyases with an ultrabroad substrate spectrum [PDF]
eLifeRecently, a new class of glycosaminoglycan (GAG) lyases (GAGases) belonging to PL35 family has been discovered with an ultrabroad substrate spectrum that can degrade three types of uronic acid-containing GAGs (hyaluronic acid, chondroitin sulfate and ...
Lin Wei +11 more
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Engineering broad-spectrum digestion of polyuronides from an exolytic polysaccharide lyase [PDF]
Biotechnology for Biofuels, 2016 Macroalgae represents a promising source of fermentable carbohydrates for use in the production of energy efficient biofuel. The primary carbohydrate in brown algae is the uronic acid-containing alginate, whereas green algae contains a significant amount of glucuronan.
Logan C. MacDonald +2 more
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Polyuronic acid degradation by polysaccharide lyase family 7 [PDF]
Acta Crystallographica Section A Foundations and Advances, 2022 M. Vuillemin +12 more
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Structural Determinants Responsible for Substrate Recognition and Mode of Action in Family 11 Polysaccharide Lyases* [PDF]
Journal of Biological Chemistry, 2009 A saprophytic Bacillus subtilis secretes two types of rhamnogalacturonan (RG) lyases, endotype YesW and exotype YesX, which are responsible for an initial cleavage of the RG type I (RG-I) region of plant cell wall pectin.
A. Ochiai +4 more
semanticscholar +3 more sources
Distinct Modes of Hidden Structural Dynamics in the Functioning of an Allosteric Polysaccharide Lyase [PDF]
ACS Central Science, 2022 Dynamics is an essential process to drive an enzyme to perform a function. When a protein sequence encodes for its three-dimensional structure and hence its function, it essentially defines the intrinsic dynamics of the molecule. The static X-ray crystal structure was thought to shed little insight into the molecule's dynamics until the recently ...
Prerana Dash, Rudresh Acharya
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Gellan lyases--novel polysaccharide lyases. [PDF]
Microbiology, 1994 A number of bacterial strains capable of degrading the bacterial exopolysaccharide gellan have been isolated by standard enrichment procedures. They include several pink-pigmented Gram-negative rod-shaped bacteria. A red-pigmented Gram-positive bacillus earlier found to degrade the exopolysaccharide xanthan from Xanthomonas campestris also showed ...
L. Kennedy, I. Sutherland
semanticscholar +3 more sources
Structural and mechanistic classification of uronic acid-containing polysaccharide lyases. [PDF]
Glycobiology, 2010 Polysaccharide lyases (PLs) have been assigned to 21 families based on their sequences, with ~ 50 singletons awaiting further classification. For 19 of these families, the structure of at least one protein is known. In this review, we have analyzed the available structural information and show that presently known PL families belong to six general ...
M. Garron, M. Cygler
semanticscholar +3 more sources
Exploring molecular determinants of polysaccharide lyase family 6–1 enzyme activity [PDF]
Glycobiology, 2021 Abstract The polysaccharide lyase family 6 (PL6) represents one of the 41 polysaccharide lyase families classified in the CAZy database with the vast majority of its members being alginate lyases grouped into three subfamilies, PL6_1–3. To decipher the mode of recognition and action of the enzymes belonging to subfamily PL6_1, we solved ...
Sébastien Violot +9 more
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