Results 241 to 250 of about 246,499 (299)

Advances in Medical Devices for Augmented Acupuncture Therapy

open access: yesAdvanced Science, EarlyView.
Traditional acupuncture therapy faces several challenges in clinical applications, such as complex operation procedures and prolonged therapeutic periods. By incorporating physical stimulations and drug delivery technologies, engineered acupuncture needles (EANs) can enhance therapeutic efficacy, improve patient compliance, as well as mitigate ...
Ruisi Cai   +7 more
wiley   +1 more source

Large‐Scale Bioprinting of Human Epiblast‐Like Models Featuring Disc‐Shaped Morphogenesis and Gastrulation Events

open access: yesAdvanced Science, EarlyView.
Large‐scale generation of disc‐shaped models mimicking human epiblast layer is achieved by bioprinting of human pluripotent stem cells using a well‐defined biomatrix. The bioactive component and physical confinement from laminin/alginate microgels, combined with the endogenous regulation of the WNT signaling pathway regulated disc‐like morphogenesis ...
Yixue Luo   +11 more
wiley   +1 more source

Developing Biomaterial‐Based mRNA Delivery System for Lung Disease Treatment

open access: yesAdvanced Science, EarlyView.
Schematic illustration of biomaterial delivery mRNA for the treatment of lung diseases. Abstract Lung disease remains a persistent global health challenge. Advances in medical research have led to innovative strategies to combat these conditions, with biomaterials emerging as a promising platform for targeted drug delivery.
Qiancheng Gu   +7 more
wiley   +1 more source

Impact of Virus‐Mediated Modifications in Bacterial Communities on the Accumulation of Soil Organic Carbon

open access: yesAdvanced Science, EarlyView.
This study illustrates the impact of viruses on carbon cycling in soils with different availabilities of carbon. In conditions of low carbon availability, viruses adopt a lysogenic lifestyle, integrate into the host genomes and facilitate the degradation of carbon.
Mingfeng Liu   +8 more
wiley   +1 more source

Volumetric Engineered 3D Drug Reservoir Against Diabetic Implant Infection via Cuproptosis‐Like Bacterial Death and Hunger‐Triggered Maintenance of Mitochondrial Integrity

open access: yesAdvanced Science, EarlyView.
This study provides a volumetric engineered 3D drug reservoir to combat diabetic implant infection. Cu‐doped quantum dots induce cuproptosis‐like bacterial death via metabolic collapse, while glucose oxidase triggers hunger‐triggered mitochondrial protection in host cells.
Dize Li   +8 more
wiley   +1 more source

Spatiotemporal Adaptations‐Driven Dynamic Thra Activation Simulates a Skin Wound Healing Response

open access: yesAdvanced Science, EarlyView.
This study uncovers the thyroid hormone receptor Thra as a pivotal regulator that spatiotemporally orchestrates dual‐phase skin repair. Epidermal Thra accelerates barrier restoration via glutathione‐driven keratin assembly, while dermal Thra establishes angiogenic niches through SAA3‐FN1‐mediated matrix remodeling.
Zeming Li   +15 more
wiley   +1 more source

Home - About - Disclaimer - Privacy