Results 21 to 30 of about 344,226 (306)

Transcriptome Analysis Reveals Possible Immunomodulatory Activity Mechanism of Chlorella sp. Exopolysaccharides on RAW264.7 Macrophages

Marine Drugs, 2021
In this study, the exopolysaccharides of Chlorella sp. (CEP) were isolated to obtain the purified fraction CEP4. Characterization results showed that CEP4 was a sulfated heteropolysaccharide.
Siwei Wu, Hongquan Liu, Siyu Li, Han Sun, Xiumiao He, Ying Huang, Han Long   +6 more
doaj   +1 more source

Heterologous expression of the pneumococcal serotype 14 polysaccharide in Lactococcus lactis requires lactococcal epsABC regulatory genes [PDF]

, 2008
The pneumococcal serotype 14 polysaccharide was produced in Lactococcus lactis by coexpressing pneumococcal polysaccharide type 14-specific genes (cpsFGHIJKL(14)) with the lactococcal regulatory and priming glucosyltransferase-encoding genes specific for
Kleerebezem, M., Masja N. Nierop Groot, Michiel Kleerebezem, Jeroen Godefrooij, Nierop Groot, M.N., Godefrooij, J.   +5 more
core   +1 more source

Polysaccharide determination in protein/polysaccharide mixtures for phase-diagram construction [PDF]

, 2010
The effect of protein removal from protein–polysaccharide mixtures on the determination of total sugar concentration for phase-diagram construction was explored by response surface methodology.
Agbenorhevi, Jacob K., Kontogiorgos, Vassilis, Jacob K. Agbenorhevi, Vassilis Kontogiorgos   +3 more
core   +1 more source

Optimization of Succinic Acid Production from Sweet Potato Powder by Actinobacillus succinogenes

Shipin gongye ke-ji, 2023
In order to raise yields and reduce production costs, the fermentation medium of succinic acid production by Actinobacillus succinogenes from sweet potato powder.
Shiyong LI, Qiuli WEI, Qionghui QIN, Shuyan LI, Fuhui CHEN, Chaodong SONG, Hongyan ZHANG, Yan QIN, Ge LIANG, Mingguo JIANG, Naikun SHEN   +10 more
doaj   +1 more source

Recombinant plants provide a new approach to the production of bacterial polysaccharide for vaccines. [PDF]

, 2014
Bacterial polysaccharides have numerous clinical or industrial uses. Recombinant plants could offer the possibility of producing bacterial polysaccharides on a large scale and free of contaminating bacterial toxins and antigens.
G. C. Whitelam (7665758), Marie Goldrick (324989), Roberts Ian S., Garry C. Whitelam (519301), Andrew, PW, Patel, Alexandra J.F., Whitelam, Garry C, Claire M. Smith (7665743), Peter W. Andrew (153608), Roberts, Ian S, Whitelam, Garry C., Patel Alexandra J. F., Roberts, IS, K. C. Gough (7665749), Glenn, S, Gough Kevin C., Andrew, Peter W, S. C. Fry (7665746), Alexandra J F Patel, Stephen C Fry, Garry C Whitelam, Kevin C Gough, Gough, KC, Sarah Glenn (519300), Fry Stephen C., Andrew Peter W., Gough, Kevin C, Whitelam, GC, Sarah Glenn, Fry, Stephen C., Claire M. Smith (519296), Roberts, Ian S., Ian S. Roberts (159693), Whitelam Garry C., Peter W Andrew, Smith, Claire M, Patel, Alexandra J F, Patel, AJ, Fry, Stephen C, Stephen C. Fry (519297), Andrew, Peter W., Kevin C. Gough (519298), Ian S Roberts, Fry, SC, Goldrick, M, Smith Claire M., Alexandra J. F. Patel (519299), Goldrick Marie, Marie Goldrick, M. Goldrick (7665755), Goldrick, Marie, Alexandra J. F. Patel (7665752), Gough, Kevin C., Glenn, Sarah, Glenn Sarah, Smith, Claire M., Claire M Smith, Smith, CM, I. S. Roberts (6341096)   +58 more
core   +1 more source

Polysaccharide degradation by lytic polysaccharide monooxygenases

Current Opinion in Structural Biology, 2019
The discovery of oxidative cleavage of glycosidic bonds by enzymes currently known as lytic polysaccharide monooxygenases (LPMOs) has had a major impact on our current understanding of the enzymatic conversion of recalcitrant polysaccharides such as chitin and cellulose.
Forsberg, Zarah, Sørlie, Morten, Petrović, Dejan, Courtade, Gaston, Aachmann, Finn, Vaaje-Kolstad, Gustav, Bissaro, Bastien, Røhr, Åsmund, Eijsink, Vincent Gh   +8 more
openaire   +6 more sources

Carbon Nanoparticles Inhibit Α-Glucosidase Activity and Induce a Hypoglycemic Effect in Diabetic Mice

Molecules, 2019
New, improved therapies to reduce blood glucose are required for treating diabetes mellitus (DM). Here, we investigated the use of a new nanomaterial candidate for DM treatment, carbon nanoparticles (CNPs).
Taili Shao, Pingchuan Yuan, Lei Zhu, Honggang Xu, Xichen Li, Shuguang He, Ping Li, Guodong Wang, Kaoshan Chen   +8 more
doaj   +1 more source

Insights into an NEk2 inhibitory profile of nitidine chloride by molecular docking and biological evaluation

BMC Chemistry, 2022
Deregulation of NEK2(NIMA-related serine/threonine 2) confers chemotherapeutic resistance to apoptosis and is closely correlated with poor prognosis in hepatocellular carcinoma (HCC).
Danni Li, Jiahao Lu, Qiying Zhang, Yuzhu Zhou, Long Li, Hua Zhu, Tong Li   +6 more
doaj   +1 more source

Polysaccharide-Based Nanomedicines Targeting Lung Cancer [PDF]

, 2022
A primary illness that accounts for a significant portion of fatalities worldwide is cancer. Among the main malignancies, lung cancer is recognised as the most chronic kind of cancer around the globe.
Obaid Afzal, Afzal, O, Almalki, WH, Dinesh Kumar Chellappan (3622100), Asif Ahmad Bhat, Altamimi, Abdulmalik S. A., Obaid Afzal (10509562), MacLoughlin, R, Brian G Olive (14513592), Almalki, Waleed Hassan, Kazmi, Imran, Alzarea, Sami I., Khalid Saad Alharbi, Dua, K, Alzarea, SI, Chellappan, DK, Asif Ahmad Bhat (14513584), Sami I. Alzarea, Dinesh Kumar Chellappan, Chellappan, Dinesh Kumar, Gaurav Gupta (316879), Fahad A. Al-Abbasi, Ronan MacLoughlin (7898939), Sachin Kumar Singh, Gupta, G, Kamal Dua, Bhat, AA, Imran Kazmi (12226378), Imran Kazmi, Abdulmalik S. A. Altamimi, Dua, Kamal, Kamal Dua (9903691), Al-Abbasi, FA, Sami I Alzarea (14513587), MacLoughlin, Ronan, Abdulmalik S A Altamimi (14513585), Alharbi, KS, Gaurav Gupta, Brian G Oliver, Kazmi, I, Bhat, Asif Ahmad, Waleed Hassan Almalki, Oliver, BG, Sachin Kumar Singh (8460930), Singh, Sachin Kumar, Afzal, Obaid, Singh, SK, Altamimi, ASA, Khalid Saad Alharbi (10515639), Waleed Hassan Almalki (10279493), Ronan MacLoughlin, Gupta, Gaurav, Oliver, Brian G, Alharbi, Khalid Saad, Al-Abbasi, Fahad A., Fahad A Al-Abbasi (7062128), Alzarea, Sami I, Al-Abbasi, Fahad A, Altamimi, Abdulmalik S A   +58 more
core   +1 more source

Folic acid modified TPGS as a novel nano-micelle for delivery of nitidine chloride to improve apoptosis induction in Huh7 human hepatocellular carcinoma

BMC Pharmacology and Toxicology, 2021
Background The development of novel and effective drugs for targeted human hepatocellular carcinoma still remains a great challenge. The alkaloid nitidine chloride (NC), a component of a traditional Chinese medicine, has been shown to have anticancer ...
Danni Li, Shaogang Liu, Jiahao Zhu, Liqun Shen, Qi ying Zhang, Hua Zhu   +5 more
doaj   +1 more source