Results 11 to 20 of about 23,350 (227)

Mechanistic Insights into Substrate Recognition and Catalysis of a New Ulvan Lyase of Polysaccharide Lyase Family 24. [PDF]

Appl Environ Microbiol, 2021
Ulvan is a major cell wall component of green algae of the genus Ulva. Many marine heterotrophic bacteria can produce extracellular ulvan lyases to degrade ulvan for a carbon nutrient. In addition, ulvan has a range of physiological bioactivities based on its specific chemical structure.
Xu F, Dong F, Sun XH, Cao HY, Fu HH, Li CY, Zhang XY, McMinn A, Zhang YZ, Wang P, Chen XL.   +10 more
europepmc   +4 more sources

Gellan lyases-novel polysaccharide lyases [PDF]

Microbiology, 1994
A number of bacterial strains capable of degrading the bacterial exopolysaccharide gellan have been isolated by standard enrichment procedures. They include several pink-pigmented Gram-negative rod-shaped bacteria. A red-pigmented Gram-positive bacillus earlier found to degrade the exopolysaccharide xanthan from Xanthomonas campestris also showed ...
L, Kennedy, I W, Sutherland
openaire   +2 more sources

Polysaccharide lyases [PDF]

FEMS Microbiology Reviews, 1995
Polysaccharide lyases are the products of various microorganisms, bacteriophage and some eukaryotes. All such enzymes cleave a hexose-1,4-alpha- or beta-uronic acid sequence by beta-elimination. They are in some examples, the only known type of enzymes degrading their polyanionic substrates.
openaire   +4 more sources

Specificities and Synergistic Actions of Novel PL8 and PL7 Alginate Lyases from the Marine Fungus Paradendryphiella salina

Journal of Fungi, 2021
Alginate is an anionic polysaccharide abundantly present in the cell walls of brown macroalgae. The enzymatic depolymerization is performed solely by alginate lyases (EC 4.2.2.x), categorized as polysaccharide lyases (PLs) belonging to 12 different PL ...
Bo Pilgaard, Marlene Vuillemin, Jesper Holck, Casper Wilkens, Anne S. Meyer   +4 more
doaj   +1 more source

Bacterial polysaccharide lyase family 33: Specificity from an evolutionarily conserved binding tunnel. [PDF]

Proc Natl Acad Sci U S A
Acidic glycans are essential for the biology of multicellular eukaryotes. To utilize them, microbial life including symbionts and pathogens has evolved polysaccharide lyases (PL) that cleave their 1,4 glycosidic linkages via a β-elimination mechanism. PL family 33 (PL33) enzymes have the unusual ability to target a diverse range of glycosaminoglycans ...
Loiodice M, Drula E, McIver Z, Antonyuk S, Baslé A, Lima M, Yates EA, Byrne DP, Coughlan J, Leech A, Mesdaghi S, Rigden DJ, Drouillard S, Helbert W, Henrissat B, Terrapon N, Wright GSA, Couturier M, Cartmell A.   +18 more
europepmc   +7 more sources

Vibrio cholerae RbmB is an α-1,4-polysaccharide lyase with biofilm-disrupting activity against Vibrio polysaccharide (VPS). [PDF]

PLoS Pathog
Many pathogenic bacteria form biofilms as a protective measure against environmental and host hazards. The underlying structure of the biofilm matrix consists of secreted macromolecules, often including exopolysaccharides. To escape the biofilm, bacteria may produce a number of matrix-degrading enzymes, including glycosidic enzymes
Weerasekera R, Moreau A, Huang X, Nam KM, Hinbest AJ, Huynh Y, Liu X, Ashwood C, Pepi LE, Paulson E, Cegelski L, Yan J, Olson R.   +12 more
europepmc   +4 more sources

Diversity and function of phage encoded depolymerases [PDF]

, 2020
Bacteriophages of the Podoviridae family often exhibit so-called depolymerases as structural components of the virion. These enzymes appear as tail spike proteins (TSPs).
Fieseler, Lars, Knecht, Leandra E., Veljkovic, Marjan   +2 more
core   +1 more source

A hierarchical classification of polysaccharide lyases for glycogenomics [PDF]

Biochemical Journal, 2010
Carbohydrate-active enzymes face huge substrate diversity in a highly selective manner using only a limited number of available folds. They are therefore subjected to multiple divergent and convergent evolutionary events. This and their frequent modularity render their functional annotation in genomes difficult in a number of cases.
Lombard, Vincent, Bernard, Thomas, Rancurel, Corinne, Brumer, Harry, Coutinho, Pedro, Henrissat, Bernard   +5 more
openaire   +4 more sources

Insights into the Influence of Signal Peptide on the Enzymatic Properties of Alginate Lyase AlyI1 with Removal Effect on Pseudomonas aeruginosa Biofilm

Marine Drugs, 2022
Most reports on signal peptides focus on their ability to affect the normal folding of proteins, thereby affecting their secreted expression, while few studies on its effects on enzymatic properties were published. Therefore, biochemical characterization
Ming-Jing Zhang, Shuai-Ting Yun, Xiao-Chen Wang, Li-Yang Peng, Chuan Dou, Yan-Xia Zhou   +5 more
doaj   +1 more source

Sustainable alginate lyases catalyzed degradation of bio-based carbohydrates

Frontiers in Chemistry, 2022
Alginate is a water-soluble and acidic polysaccharide derived from the cell wall and intercellular substance of brown algae. It is widely distributed in brown algae, such as Laminaria, Sargassum, and Macrocystis, etc.
Zhiguo Zheng, Ali Dai, Yonggui Liu, Tingting Li   +3 more
doaj   +1 more source