Results 21 to 30 of about 23,515 (209)

Bacterial polysaccharide lyase family 33: Specificity from an evolutionarily conserved binding tunnel. [PDF]

Proc Natl Acad Sci U S A
Acidic glycans are essential for the biology of multicellular eukaryotes. To utilize them, microbial life including symbionts and pathogens has evolved polysaccharide lyases (PL) that cleave their 1,4 glycosidic linkages via a β-elimination mechanism. PL family 33 (PL33) enzymes have the unusual ability to target a diverse range of glycosaminoglycans ...
Loiodice M, Drula E, McIver Z, Antonyuk S, Baslé A, Lima M, Yates EA, Byrne DP, Coughlan J, Leech A, Mesdaghi S, Rigden DJ, Drouillard S, Helbert W, Henrissat B, Terrapon N, Wright GSA, Couturier M, Cartmell A.   +18 more
europepmc   +7 more sources

Vibrio cholerae RbmB is an α-1,4-polysaccharide lyase with biofilm-disrupting activity against Vibrio polysaccharide (VPS). [PDF]

PLoS Pathog
Many pathogenic bacteria form biofilms as a protective measure against environmental and host hazards. The underlying structure of the biofilm matrix consists of secreted macromolecules, often including exopolysaccharides. To escape the biofilm, bacteria may produce a number of matrix-degrading enzymes, including glycosidic enzymes
Weerasekera R, Moreau A, Huang X, Nam KM, Hinbest AJ, Huynh Y, Liu X, Ashwood C, Pepi LE, Paulson E, Cegelski L, Yan J, Olson R.   +12 more
europepmc   +4 more sources

A hierarchical classification of polysaccharide lyases for glycogenomics [PDF]

Biochemical Journal, 2010
Carbohydrate-active enzymes face huge substrate diversity in a highly selective manner using only a limited number of available folds. They are therefore subjected to multiple divergent and convergent evolutionary events. This and their frequent modularity render their functional annotation in genomes difficult in a number of cases.
Lombard, Vincent, Bernard, Thomas, Rancurel, Corinne, Brumer, Harry, Coutinho, Pedro, Henrissat, Bernard   +5 more
openaire   +4 more sources

Insights into the Influence of Signal Peptide on the Enzymatic Properties of Alginate Lyase AlyI1 with Removal Effect on Pseudomonas aeruginosa Biofilm

Marine Drugs, 2022
Most reports on signal peptides focus on their ability to affect the normal folding of proteins, thereby affecting their secreted expression, while few studies on its effects on enzymatic properties were published. Therefore, biochemical characterization
Ming-Jing Zhang, Shuai-Ting Yun, Xiao-Chen Wang, Li-Yang Peng, Chuan Dou, Yan-Xia Zhou   +5 more
doaj   +1 more source

The regulatory and transcriptional landscape associated with carbon utilization in a filamentous fungus. [PDF]

, 2020
Filamentous fungi, such as Neurospora crassa, are very efficient in deconstructing plant biomass by the secretion of an arsenal of plant cell wall-degrading enzymes, by remodeling metabolism to accommodate production of secreted enzymes, and by enabling ...
Benz, J Philipp, Blow, Matthew J, Calhoun, Sara, Dietschmann, Axel, Glass, N Louise, Grigoriev, Igor V, Huberman, Lori B, Kowbel, David J, Lee, Juna, Lipzen, Anna, Monti, Remo, O'Malley, Ronan C, Singan, Vasanth R, Thieme, Nils, Wu, Vincent W, Xiong, Yi   +15 more
core   +3 more sources

Sustainable alginate lyases catalyzed degradation of bio-based carbohydrates

Frontiers in Chemistry, 2022
Alginate is a water-soluble and acidic polysaccharide derived from the cell wall and intercellular substance of brown algae. It is widely distributed in brown algae, such as Laminaria, Sargassum, and Macrocystis, etc.
Zhiguo Zheng, Ali Dai, Yonggui Liu, Tingting Li   +3 more
doaj   +1 more source

Biochemical characteristics and molecular mechanism of an exo-type alginate lyase VxAly7D and its use for the preparation of unsaturated monosaccharides

Biotechnology for Biofuels, 2020
Background As the most abundant polysaccharide in brown algae, alginate has become a promising economical material for bioethanol production. Recently, exo-type alginate lyases have received extensive attention because the unsaturated monosaccharides ...
Luyao Tang, Ying Wang, Shan Gao, Hao Wu, Danni Wang, Wengong Yu, Feng Han   +6 more
doaj   +1 more source

Microbial Regulation of Deterioration and Preservation of Salted Kelp under Different Temperature and Salinity Conditions

Foods, 2021
High salinity is an effective measure to preserve kelp, but salted kelp can still deteriorate after long-term preservation. In order to clarify the key conditions and microbial behavior of salted kelp preservation, 10% (S10), 20% (S20), and 30% (S30 ...
Wei Wei, Xin Zhang, Zhaozhi Hou, Xinyu Hu, Yuan Wang, Caizheng Wang, Shujing Yang, Henglin Cui, Lin Zhu   +8 more
doaj   +1 more source

Genes for degradation and utilization of uronic acid-containing polysaccharides of a marine bacterium Catenovulum sp. CCB-QB4 [PDF]

PeerJ, 2021
Background Oligosaccharides from polysaccharides containing uronic acids are known to have many useful bioactivities. Thus, polysaccharide lyases (PLs) and glycoside hydrolases (GHs) involved in producing the oligosaccharides have attracted interest in ...
Go Furusawa, Nor Azura Azami, Aik-Hong Teh   +2 more
doaj   +2 more sources

Polysaccharide lyases from gellan-producing Sphingomonas spp. [PDF]

Microbiology, 1996
A number ofSphingomonasstrains capable of synthesizing the bacterial exopolysaccharide gellan and related polymers were shown to possess constitutive gellanase activity. In each case, the degradation of deacylated gellan was due to extracellular, eliminase-type enzymes (lyases) which cleave the sequence …ß-D-glucosyl 1,4-ß-D-glucuronosyl… in the ...
Lynn, Kennedy, Ian W, Sutherland
openaire   +2 more sources