Structure and Polymannuronate Specificity of a Eukaryotic Member of Polysaccharide Lyase Family 14. [PDF]
J Biol Chem, 2017 Alginate is an abundant algal polysaccharide, composed of β-d-mannuronate and its C5 epimer α-l-guluronate, that is a useful biomaterial in cell biology and tissue engineering, with applications in cancer and aging research. The alginate lyase (EC 4.2.2.3) from Aplysia kurodai, AkAly30, is a eukaryotic member of the polysaccharide lyase 14 (PL-14 ...
Qin HM +8 more
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A novel exo-lytic and disaccharide-yielding glycosaminoglycan lyase from a marine-derived polysaccharide-degrading actinobacterium Microbacterium sp. strain WS15 [PDF]
Frontiers in MicrobiologyIntroductionGlycosaminoglycan (GAG) lyases play key roles in preparing oligosaccharides, treating human diseases, and learning relationships between complex structures and various functions of carbohydrates.
Peng Li +8 more
doaj +2 more sources
Vibrio cholerae RbmB is an α-1,4-polysaccharide lyase with biofilm-disrupting activity against Vibrio polysaccharide (VPS). [PDF]
PLoS PathogMany pathogenic bacteria form biofilms as a protective measure against environmental and host hazards. The underlying structure of the biofilm matrix consists of secreted macromolecules, often including exopolysaccharides. To escape the biofilm, bacteria may produce a number of matrix-degrading enzymes, including glycosidic enzymes
Weerasekera R +12 more
europepmc +4 more sources
Engineering broad-spectrum digestion of polyuronides from an exolytic polysaccharide lyase. [PDF]
Biotechnol Biofuels, 2016 Macroalgae represents a promising source of fermentable carbohydrates for use in the production of energy efficient biofuel. The primary carbohydrate in brown algae is the uronic acid-containing alginate, whereas green algae contains a significant amount of glucuronan.
MacDonald LC, Weiler EB, Berger BW.
europepmc +4 more sources
Characterization of a New Cold-Adapted and Salt-Activated Polysaccharide Lyase family 7 Alginate Lyase from Pseudoalteromonas sp. SM0524 [PDF]
Frontiers in Microbiology, 2016 Marine bacterial alginate lyases play a role in marine alginate degradation and carbon cycling. Although a large number of alginate lyases have been characterized, reports on alginate lyases with special characteristics are still rather less.
Xiu-Lan Chen +19 more
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Novel Molecular Insights into the Catalytic Mechanism of Marine Bacterial Alginate Lyase AlyGC from Polysaccharide Lyase Family 6 [PDF]
Journal of Biological Chemistry, 2017 Bin-Bin Xie, Fei Xu, Chun-Yang Li
exaly +2 more sources
Marine Drugs, 2021 Alginate, a natural polysaccharide derived from brown seaweed, is finding multiple applications in biomedicine via its transformation through chemical, physical, and, increasingly, enzymatic processes.
Thi Nhu Thuong Nguyen +4 more
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Current Research in Food Science, 2023 Alginate lyase is essential for the production of alginate oligosaccharides (AOSs), which exhibit diverse bioactivities and have numerous applications in the food and pharmaceutical industries.
Yuting Zheng +5 more
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Gellan lyases-novel polysaccharide lyases [PDF]
Microbiology, 1994 A number of bacterial strains capable of degrading the bacterial exopolysaccharide gellan have been isolated by standard enrichment procedures. They include several pink-pigmented Gram-negative rod-shaped bacteria. A red-pigmented Gram-positive bacillus earlier found to degrade the exopolysaccharide xanthan from Xanthomonas campestris also showed ...
L, Kennedy, I W, Sutherland
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Journal of Fungi, 2021 Alginate is an anionic polysaccharide abundantly present in the cell walls of brown macroalgae. The enzymatic depolymerization is performed solely by alginate lyases (EC 4.2.2.x), categorized as polysaccharide lyases (PLs) belonging to 12 different PL ...
Bo Pilgaard +4 more
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