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Efficacy of Pneumococcal Polysaccharide Vaccines

Clinical Infectious Diseases, 1981
due to pneumococcal infection. Estimates based on data obtained in this country after licensure of the vaccine suggest that the efficacy in certain groups may be low:
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Polysaccharide Meningococcal Vaccines—Current Status

Hospital Practice, 1979
Two separate periods of intensive research, with a 25-year hiatus after the advent of the sulfonamides, have resulted in two good, but imperfect, antimeningococcal vaccines--against serogroups A and C. Neither is recommended for routine use, but both have been effective in halting epidemics.
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[Polysaccharide subunit vaccines].

La Revue du praticien, 1995
The polysaccharide capsules of many germs (pneumococcus, meningococcus, Haemophilus b, salmonella, etc.) can induce synthesis of protective antibodies in man. The development of many vaccines has been based on this phenomenon. Unfortunately, the polysaccharide antigens cannot trigger an immune response before the age of 2 years.
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Bacterial Polysaccharide Vaccines

2011
Capsulated bacteria, Gram-positive or Gram-negative, cause a variety of infections in man. Prominent among them are streptococci of Lancefield’s groups A, B, and C, staphylococci, meningococci, Haemophilus influenzae type b, klebsiellas, Escherichia coli, and Salmonella typhi, to name but some.
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Polysaccharide vaccines

Annales de l'Institut Pasteur / Microbiologie, 1985
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Chemically Modified Capsular Polysaccharides as Vaccines

1988
Capsular polysaccharides have assumed an important role as vaccines against disease caused by bacteria in humans. The concept of using pure definable polysaccharides devoid of their accompanying complex bacterial mass is technically elegant and is obviously capable of extension into other areas of immunoprophylaxis.
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Preparation of Polysaccharide-Conjugate Vaccines

2003
Peeters, CC   +7 more
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