Results 11 to 20 of about 257,706 (241)
Beeswax and resin are the main components of propolis, both of which are hydrophobic. The use of emulsifiers helps to improve the extraction of active propolis compounds and makes them more widely used.
Felix Shih-Hsiang Hsiao +7 more
doaj +1 more source
Polysorbates (PS 20 and PS 80) are the most widely used surfactants in biopharmaceutical formulations to protect proteins from denaturation, aggregation, and surface adsorption.
Hailong Zhang +7 more
doaj +1 more source
The amount of polysorbate 80 in pharmaceutical formulations affects the product quality and efficacy. A reliable test method is required to quantify the amount of Polysorbate 80 present in the drug product formulations.
Bikash Mondal +3 more
doaj +1 more source
Symurban Nanocrystals for Advanced Anti-Pollution Skincare [PDF]
Several of most common dermatoses worldwide, e.g., psoriasis and atopic dermatitis, are worsened in their clinical picture when the skin is regularly exposed to an increased air pollution level, e.g., particulate matter.
Köpke, Daniel, Pyo, Sung Min
core +1 more source
Insights into ultra-low affinity lipase-antibody noncovalent complex binding mechanisms
Detection of host cell protein (HCP) impurities is critical to ensuring that recombinant drug products, including monoclonal antibodies (mAbs), are safe.
Elizabeth Sara Hecht +11 more
doaj +1 more source
Evaluation of Patients with Vaccine Allergies Prior to mRNA-Based COVID-19 Vaccination
During the initial rollout of coronavirus disease 2019 (COVID-19) vaccination in Singapore, the Ministry of Health (MOH) issued a recommendation that patients with a history of any previous vaccine allergy be referred to an allergist for further review ...
Xin Rong Lim +12 more
doaj +1 more source
Polysorbate 80 blocked a peripheral sodium channel, Na1.7, and reduced neuronal excitability
Polysorbate 80 is a non-ionic detergent derived from polyethoxylated sorbitan and oleic acid. It is widely used in pharmaceuticals, foods, and cosmetics as an emulsifier. Na v 1.7 is a peripheral sodium channel that is highly expressed in sympathetic and
Ryeong-Eun Kim, Jin-Sung Choi
doaj +1 more source
Destabilization of α-helical structure in solution improves bactericidal activity of antimicrobial peptides: Opposing effects on bacterial and viral targets [PDF]
We have previously examined the mechanism of antimicrobial peptides on the outer membrane of vaccinia virus. Here we show that the formulation of peptides LL37 and magainin-2B amide in polysorbate 20 (Tween-20™) results in greater reductions in virus ...
Beck, Konrad +4 more
core +2 more sources
Objectives. We hereby describe an improvement of a previously developed quantification technique for polysorbate 80 in biopharmaceutical formulations (darbepoetin alfa and eculizumab) and report the validation of the new approach.Methods. Polysorbate was
A. S. Seregin +4 more
doaj +1 more source
Development of a Potentiometric Sensor Sensitive to Polysorbate 20 [PDF]
Polyoxyethylated sorbitans (polysorbates) are widely used in the chemical, pharmaceutical, and cosmetic industries, but only quantitative determination is used mainly for chromatographic methods.
Kotok, V. (Valerii) +4 more
core +2 more sources

