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Polyunsaturated fatty acids and inflammation
IUBMB Life, 2015AbstractInflammation is a protective process for life that aims to restore body homeostasis by targeting the injury and by inducing repair mechanisms. This process can also become excessive and lead to chronic inflammation and organ fibrosis. Polyunsaturated fatty acids play a key role in inflammatory processes and their resolution.
Marion-Letellier, Rachel +2 more
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Polyunsaturated Fatty Acids and Ethanol
Advances in Alcohol & Substance Abuse, 1988Ethanol exposure leads to a loss in membrane polyunsaturated fatty acids (PUFA). It is proposed that polyunsaturated species of phospholipids are not randomly distributed, but are concentrated in the cytosolic leaflets of the plasma membrane and are preferentially associated with membrane proteins. These lipids affect the physical state of environments
Norman Salem, John W. Karanian
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Polyunsaturated Fatty Acids: Biotechnology
Critical Reviews in Biotechnology, 2006Polyunsaturated fatty acids like EPA and DHA have attracted a great attention due to their beneficial effects on human health. At present, fish oil is the major source of EPA and DHA. Various alternative sources are being explored to get these essential fatty acids.
Dnyaneshwar Warude +2 more
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Polyunsaturated Fatty Acids and Cardiovascular Disease
Current Pharmaceutical Design, 2009Several observational and experimental studies show the beneficial effects of omega-3 poly-unsaturated fatty acids (PUFA) in cardiovascular disease. The results from such studies justify supplementation of omega-3 PUFA in primary and secondary prevention of several clinical conditions, including coronary heart disease, sudden cardiac death and heart ...
Calzolari I +3 more
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Enzymatic Purification of Polyunsaturated Fatty Acids.
Journal of Bioscience and Bioengineering, 2001Polyunsaturated fatty acids (PUFAs) have various physiological functions. Of these, ethyl eicosapentaenoate is industrially purified and used as a medicine. Other PUFAs, such as docosahexaenoic acid (DHA), gamma-linolenic acid (GLA), and arachidonic acid (AA), are also expected to be used as pharmaceutical agents; however, their industrial purification
Akio Sugihara +2 more
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Polyunsaturated Fatty Acids and Cardiovascular Health
Nutrition Reviews, 2004Epidemiologic studies have shown a beneficial association between polyunsaturated fatty acid (PUFA), specifically linoleic acid (C18:2, n-6), intake and cardiovascular disease morbidity and mortality. Clinical studies have shown that n-6 PUFAs have the most potent cholesterol-lowering effects of the individual fatty acid classes, and emerging evidence ...
Kari D Hecker +2 more
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Regulation of the metabolism of polyunsaturated fatty acids
Scandinavian Journal of Clinical and Laboratory Investigation, 1988The object of the present work has been to assess some aspects of the control of the metabolism of polyunsaturated fatty acids. In these studies we have used isolated cells; hepatocytes and cardiac myocytes from rat, and lymphocytes and fibroblasts from humans.
Tor-Arne Hagve +3 more
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Polyunsaturated Fatty Acids in Emerging Psychosis
Current Pharmaceutical Design, 2012The role of polyunsaturated fatty acids and their metabolites for the cause and treatment of psychotic disorders are widely discussed. The efficacy as an augmenting agent in chronic schizophrenia seems to be small or not present, however epidemiological data, as well as some recent controlled studies in emerging psychosis point towards possible ...
Paolo Fusar-Poli +8 more
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The Polyunsaturated Fatty Acids of Microorganisms
1966Publisher Summary This chapter discusses the polyunsaturated fatty acids of microorganisms. Polyunsaturated or polyenoic fatty acids are those long-chain fatty acids that include two or more double bonds in the molecule. It is widely accepted that bacteria are incapable of synthesizing polyenoic fatty acids, and this generalization applies equally to
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Polyunsaturated fatty acids in infant nutrition
Acta Paediatrica, 1994The availability of long‐chain polyunsaturated fatty acids (LCP), such as arachidonic (C20:4n‐6) and docosahexaenoic (C22:6n‐3) acids, is important for early human growth and development. The capacity for endogenous synthesis of LCP from the precursor fatty acids lineoleic (C18:2n‐6) and alpha‐linolenic (C18:3n‐3) acid is limited in preterm and ...
Berthold Koletzko, Tamás Decsi
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