The Inflammatory Roles of n-3 and n-6 Polyunsaturated Fatty Acids in COPD: Clinical Implications and Underlying Mechanisms. [PDF]
Wang Y +9 more
europepmc +1 more source
Peroxiredoxin 4 Involved in Spermatogenesis by Affecting Oxidative Stress and Ferroptosis
ABSTRACT Background The main functions of testes are sperm production and androgen secretion in testicular befitting microenvironment. Excessive level of the reactive oxygen species (ROS) from metabolism and cellular events can lead to oxidative stress (OS) and ferroptosis, which injure the functions of mitochondria and endoplasmic reticulum (ER) of ...
Shuning Yuan +10 more
wiley +1 more source
Supplementation with Polyunsaturated Fatty Acids as the Main Dietary Factor Is Associated with the Omega-3 Index in Lithuanian Professional Athletes. [PDF]
Baranauskas M +3 more
europepmc +1 more source
Amyloid‐β aggregates induce vasculopathy via ferroptosis in brain endothelial cells
Blood–brain barrier (BBB) disruption is evident in brains with amyloidopathy. In this study, we demonstrate that amyloid β (Aβ) drives abnormal lipid metabolism and lipid droplet formation in brain endothelial cells, leading to lipid peroxidation and ferroptosis.
Suhyeon Son +7 more
wiley +1 more source
The association between omega-3 and omega-6 polyunsaturated fatty acids and 3 cardiac inflammatory diseases: A Mendelian randomization study. [PDF]
Song Z +7 more
europepmc +1 more source
Untargeted multiomic profiling of cerebrospinal fluid reveals that proteomic, but not lipidomic, signatures robustly distinguish ALS patients from controls and stratify individuals by survival, highlighting marked molecular differences between short survival and long survival disease.
Sergio Roca‐Pereira +19 more
wiley +1 more source
Altered polyunsaturated fatty acids and oxylipins profile in Behçet's disease. [PDF]
Ben-Fradj MK +6 more
europepmc +1 more source
Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?
Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli +7 more
wiley +1 more source
Effects of polyunsaturated fatty acids on gastric cancer immunity and immunotherapy. [PDF]
Wu D +6 more
europepmc +1 more source

