Results 61 to 70 of about 21,762 (254)

PoN-S: A Systematic Approach for Applying the Physics of Notation (PoN) [PDF]

, 2016
Visual Modeling Languages (VMLs) are important instruments of communication between modelers and stakeholders. Thus, it is important to provide guidelines for designing VMLs. The most widespread approach for analyzing and designing concrete syntaxes for VMLs is the so-called Physics of Notation (PoN).
Maria das Graças da Silva Teixeira, Glaice Kelly Quirino, Frederik Gailly, Ricardo de Almeida Falbo, Giancarlo Guizzardi, Monalessa Perini Barcellos   +5 more
openaire   +2 more sources

Early‐stage health technology assessment of a curative gene therapy for multiple sclerosis

British Journal of Clinical Pharmacology, EarlyView.
Aims Multiple sclerosis (MS) is associated with significant early morbidity, reduced life expectancy and substantial healthcare and societal costs. The primary objective of this study is to assess the early cost‐effectiveness potential of a novel gene therapy, IMMUTOL, for MS compared with current high‐efficacy treatment sequences.
Attila Imre, Balázs Nagy, Rok Hren
wiley   +1 more source

Mapping opioid exposure through prescription data and postmortem analysis of opioid drugs in multiple tissues

British Journal of Clinical Pharmacology, EarlyView.
Background and Purpose Although opioids are central to end of life (EoL) care, tissue‐level opioid exposure remains poorly understood. The objective of this study was to characterize the relationship between prescription‐derived morphine equivalent daily dose (MEDD) and measured morphine concentrations across multiple organs.
Niamh Higgins, Alan Wells, Nimish Patel, Nicole Muttera, Mattia Trunfio, Alessandra Manca, Amedeo De Nicolò, Micol Ferrara, Stefano Bonora, Jessica Cusato, Alice Palermiti, Antonio D'Avolio, Marissa Borochoff, Patricia K. Riggs, Elizabeth Hastie, Rabia S. Atayee, Stephanie Solso, Cheryl Dullano, Vanessa Gomez‐Moreno, Tara Tenenbaum, Robert Deiss, Davey M. Smith, Antoine Chaillon, Sara Gianella   +23 more
wiley   +1 more source

Machine Learning‐Based PAT Tool for Real‐Time Residual Moisture Monitoring in Lyophilized Biopharmaceuticals Using NIR Spectroscopy

Biotechnology and Bioengineering, EarlyView.
ABSTRACT There is a growing demand in the pharmaceutical industry to optimize analytical methodologies, reducing time and resource consumption while ensuring rapid process development and cost‐efficient manufacturing. Indeed, Food and Drug Administration (FDA) introduced the Process Analytical Technology (PAT) as an initiative enabling manufacturers to
Samuele Fiorenza, Mariapia D'Urso, Ambra Massei, Nunzia Falco, Davide Fissore, Enza Torino   +5 more
wiley   +1 more source

What drives animal responses to high severity fire? The role of functional traits

Biological Reviews, EarlyView.
ABSTRACT Fire regimes are changing worldwide, with increases in the frequency, extent, and severity of fires posing growing risks to biodiversity. Fire severity – the degree of habitat alteration following fire – strongly influences both immediate survival and long‐term recovery of fauna.
Grace A. Vielleux, Trent D. Penman, Victoria A. Reynolds, Matthew H. Swan   +3 more
wiley   +1 more source

Rising Strong: Cultivating Resilience in Edible City Entrepreneurship. Insights Into the Landscape of Urban Food Initiatives

Business Strategy and the Environment, EarlyView.
ABSTRACT In response to growing global challenges, this study explores how social entrepreneurship within the Edible City movement contributes to building resilient, sustainable, and equitable urban food systems. Drawing on semistructured interviews with over 70 stakeholders across five cities—Berlin, Andernach, Oslo, Rotterdam, and Havana—we ...
Ina Säumel, Stephanie Ligan, Alice Bischof, Edi Emilov Ivanov, Laura Martinez‐Izquierdo, Sara Noémie Plassnig, Marisa Pettit   +6 more
wiley   +1 more source

ESG Controversies in Global Firms: A Black Mark?

Business Strategy and the Environment, EarlyView.
ABSTRACT Despite increasing attention paid by companies to sustainability, there is still evidence of environmental, social and governance (commonly referred to as ESG) scandals. As research on this topic is scant, this paper aims to analyse the impact of ESG controversies on firms' sustainability practices, that is, ESG policies, as well as ...
Beatrice Bais, Guido Orzes, Marco Sartor
wiley   +1 more source

Revisiting the Latin Vocabulary of Terminologia Histologica: II. Adjectives and Participles

Clinical Anatomy, EarlyView.
ABSTRACT Terminologia Histologica, the international standard nomenclature of human histology and cytology, contains 1093 Latin words that appear to be used as adjectives. Among these, we identified 56 (5%) with a variety of linguistic issues, including typographical or spelling errors, less favored spelling variants, and several unfortunate word ...
Paul E. Neumann, Mélanie Houle, Stephen Russell, Andrea Barta, Katalin Delbó, Katalin Fogarasi, Nicolás E. Ottone, Mariano del Sol   +7 more
wiley   +1 more source

PROGETTO MIAPI MONITORAGGIO E INDIVIDUAZIONE DELLE AREE POTENZIALMENTE INQUINATE

GEOmedia, 2015
The MIAPI Project (Detection And Monitoring Of Potentially Polluted Areas) is a cooperation between the Carabinieri Force and the Ministry of the Environment.
Laura Petriglia, Christian Peloso, Salvatore Costabile   +2 more
doaj  

The Indonesian National Sports Games (PON): Expectations and Reality

Jurnal Pendidikan Jasmani dan Olahraga, 2019
This paper describes an empirical study about the expectation and reality of the Indonesian NationalSportsGames (PON) aftertheregulationaboutnationalsportsystemcameintoforce in 2005.
Amung Ma'mun
doaj   +1 more source