Results 111 to 120 of about 20,745 (266)

Susceptibility of PON1/PON2 Genetic Variations to Ischemic Stroke Risk in a Chinese Han Population

open access: yesPharmacogenomics and Personalized Medicine, 2020
Yuqin Pan,1,* Bangshun He,1,* Huiling Sun,1 Tao Xu,1 Bei Pan,1 Shukui Wang,1 Yanping Mei2 1General Clinical Research Center, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu Province, 210006, People’s Republic of China ...
Pan Y   +6 more
doaj  

Investigation of the effects of Terminalia chebula seed hydroalcoholic extract on Paraoxonase1 enzyme activity in rats [PDF]

open access: yesJournal of Shahrekord University of Medical Sciences
Background and aims: Paraoxonase 1 (PON1) is related to high-density lipoprotein (HDL) in serum and protects against low-density lipoprotein (LDL) oxidation. This study aimed to investigate the effects of Terminalia chebula on PON1 in hyperlipidemic rats
Parastoo Taghipour   +5 more
doaj   +1 more source

Oxidative stress products in type 2 diabetes and their relation to paraoxonase 1 activity [PDF]

open access: yes, 2011
The present study indicated a significant increase in the serum advanced oxidn. protein products (AOPP) and malondialdehyde (MDA) a marker of lipid peroxidn., in diabetic group compared to control group. AOPP was found to be pos. correlated with MDA and
Ahmed Qahtan, .   +2 more
core  

PON1 as a model for integration of genetic, epigenetic, and expression data on candidate susceptibility genes

open access: yesEnvironmental epigenetics, 2015
Recent genome- and epigenome-wide studies demonstrate that the DNA methylation is controlled in part by genetics, highlighting the importance of integrating genetic and epigenetic data. To better understand molecular mechanisms affecting gene expression,
K. Huen   +4 more
semanticscholar   +1 more source

Potential cardiovascular risk protection of bilirubin in end-stage renal disease patients under hemodialysis [PDF]

open access: yes, 2014
We evaluated the potential cardiovascular risk protection of bilirubin in hemodialysis (HD) patients. An enlarged set of studies were evaluated in 191 HD patients, including hematological study, lipid profile, iron metabolism, nutritional, inflammatory ...
Belo, L.   +12 more
core   +4 more sources

Royal jelly maintains telomere length and antioxidant parameters in the pancreas of streptozotocin-induced rats

open access: yesTrakya University Journal of Natural Sciences
Background: Streptozotocin (STZ) is an agent with selective toxicity targeting pancreatic β-cells and is commonly used to establish models of pancreatic damage.
Selcen Çakır
doaj   +1 more source

Development of an immunoblot assay with infrared fluorescence to quantify paraoxonase 1 in serum and plasma

open access: yesJournal of Lipid Research, 2008
Paraoxonase 1 (PON1) requires calcium for activity and is inactivated in the presence of EDTA. Because of this, studies to date have used serum or heparinized plasma for both activity and mass assays of PON1.
Philip W. Connelly   +4 more
doaj   +1 more source

The effects of Purslane (Portulaca oleracea L.) on serum level of lipids, lipoproteins and paraoxanase 1(PON1) activity in hypercholesterolemia patients [PDF]

open access: yes, 2012
Some unverified reports around the world demonstrated that Purslane has therapeutic effects on some conditions. The aim of this study was to compare the effects of Purslane and Lovastatin therapy in decreasing serum lipids, lipoproteins, and paraoxanase1
Farrokhi, Effat.   +4 more
core  

HDL subfraction distribution of paraoxonase-1 and its relevance to enzyme activity and resistance to oxidative stress

open access: yesJournal of Lipid Research, 2008
The subfraction distribution of HDL-associated peptides has implications for their functions and the impact of pathological modifications to lipoprotein metabolism on these functions.
Xenia Moren   +4 more
doaj   +1 more source

Somatic Gene Therapy in the Prevention of Toxic Effects of Organophosphate Agents

open access: yesВестник войск РХБ защиты
Medical intervention in poisoning by organophosphate toxic agents (OPA) using atropine sulfate, 2-pyridinaldoxymethyl chloride (2-PAM), diazepam and other similar drugs can prevent the fatal outcome of poisoning.
J. Lakota
doaj   +1 more source

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