Results 111 to 120 of about 16,258 (219)

Serum paraoxonase 1 (PON1) measurement: an update

BMC Veterinary Research, 2014
Paraoxonase 1 (PON1) is a widely studied enzyme based on its protective role against poisoning by organophosphate (OP) metabolites of specific OP insecticides and in vascular disease, as well as its use as biomarker of diseases involving oxidative stress,
J. Cerón, F. Tecles, A. Tvarijonaviciute   +2 more
semanticscholar   +1 more source

Paraoxonase (PON1) and Detoxication of Nerve Agents

, 2015
Paraoxonase (PON1) is a serum and liver enzyme that can hydrolyze in vitro a number of organophosphorus (OP) compounds, including the active metabolites of specific OP insecticides, and certain OP nerve agents such as sarin and soman.
Furlong C. E., Costa L. G., Cole T. B., Toby B. Cole, Lucio G. Costa, Clement E. Furlong   +5 more
core   +1 more source

Evaluation of Paraoxonase1 Polymorphisms in Hypothyroid Patients and Their Relationship with Paraoxonase Activity and Serum Lipids

Endocrinology Research and Practice, 2019
Objective: The risk for atherosclerosis increases in hypothyroidism, although its associated mode of pathogenesis has not been determined yet. Paraoxonase1 (PON1) is an enzyme that is antioxidative and antiatherogenic. This study was planned to determine
Ayşen CANİKLİOĞLU, Gülden BAŞKOL, Fahri BAYRAM, Yusuf ÖZKUL, Ferhan ELMALI, İlkay ÇAKIR, Meral MERT, Nahide EKİCİ GÜNAY   +7 more
doaj   +1 more source

Royal jelly maintains telomere length and antioxidant parameters in the pancreas of streptozotocin-induced rats

Trakya University Journal of Natural Sciences
Background: Streptozotocin (STZ) is an agent with selective toxicity targeting pancreatic β-cells and is commonly used to establish models of pancreatic damage.
Selcen Çakır
doaj   +1 more source

PON1-108 TT and PON1-192 RR genotypes are more frequently encountered in Greek PCOS than non-PCOS women, and are associated with hyperandrogenaemia

, 2013
Objective To investigate the frequencies of three paraoxonase (PON)1 polymorphisms in Greek polycystic ovary syndrome (PCOS) and non-PCOS women, and their genotypes association with hyperandrogenaemia and insulin resistance.
Paltoglou, George, Gazouli, Maria, Creatsas, George, Tavernarakis, George, Deligeoroglou, Efthimios, Vlassi, Margarita, Mastorakos, George, Christopoulos, Panagiotis   +7 more
core  

Organophosphate pesticide exposure, PON1, and neurodevelopment in school-age children from the CHAMACOS study

Environmental Research, 2014
Introduction Organophosphate (OP) pesticides remain widely used in agriculture. Previously, we reported that PON1 genotype was directly associated with neurodevelopment at age two, and that PON1 genotype may increase susceptibility to OP exposure ...
B. Eskenazi, K. Kogut, K. Huen, K. Harley, M. Bouchard, A. Bradman, Dana Boyd-Barr, Caroline B. Johnson, Nina T. Holland   +8 more
semanticscholar   +1 more source

Paraoxonase 1 (PON1) modulates the toxicity of mixed organophosphorus compounds

, 2009
A transgenic mouse model of the human hPON1(Q192R) polymorphism was used to address the role of paraoxonase (PON1) in modulating toxicity associated with exposure to mixtures of organophosphorus (OP) compounds.
JANSEN K. L., PARK S. S., COLE T. B., COSTA, Lucio Guido, FURLONG C. E.   +4 more
core   +1 more source

PON1 paraoxonase activities in the healthy subjects and the ACS patients based on their PON1 192 genotype.

, 2015
The PON1 Q192R genotype was determined by RT-PCR. PON1 paraoxonase activity was determined by measuring paraoxon absorbance at 412 nm.
Pamela Camponova (779670), Abdelghani Bounafaa (779663), Abdelouahed Khalil (3826456), Abdelkhalid Essamadi (779673), Hicham Berrougui (779664), Najoua Yamoul (779671), Abderrahmane Moujahid (779668), Abdallah Bagri (779667), Olivier Kamtchueng Simo (779672), Noreddine Ghalim (779665), Souad Ikhlef (779669), Boubker Nasser (779666)   +11 more
core   +1 more source

U?INEK ANAEROBNEGA TRENINGA NA AKTIVNOST SERUMSKE PARAOKSONAZE 1 (PON1) IN VLOGA POLIMORFIZMA PON1-L55M [PDF]

Paraoxonase (PON) enzyme family (paraoxonase 1, 2 and 3) has antiatherosclerotic properties. The decreased PON1 enzyme activity (EA), PON1 level and PON1-L55M polymorphism (PON1P) are risk factors for atherosclerosis.
Asikovali, Semih, Sevilmis, Ezgi, Vural, Faik, Kiliç, Çağan, Yigittürk, Oya, Durmaz, Burak, Özçaldiran, Bahtiyar   +6 more
core   +2 more sources

Association of PON-1 Genes (Q192R and L55M) Polymorphism with Cardiovascular Disease in Type 2 Diabetes Mellitus in Indian Population

Journal of Medical Sciences and Health
Background: Paraoxonase 1 (PON1) is known to modulate the antioxidant and anti-inflammatory role of HDL and may protect against cardiovascular complications in Type 2 Diabetes Mellitus (T2DM).
Shilpa Suneja, Dhivya S, Deepa Haldar, Rohit Kumar, Alka Ramteke   +4 more
doaj   +1 more source