Results 121 to 130 of about 16,258 (219)

Differential hydrolysis of homocysteine thiolactone by purified human serum 192Q and 192R PON1 isoenzymes

, 2011
Human serum paraoxonase 1 (PON1) is a HDL-associated enzyme that catalyzes the hydrolysis of a variety of aromatic carboxylic acid esters and several organophosphates.
Kamer Kılınç, Demirpence, Ediz, Kilinc, Kamer, Tülin Bayrak, Ediz Demirpençe, Bayrak, Tulin, Ahmet Bayrak, Bayrak, Ahmet   +7 more
core   +1 more source

Structure-Activity relationship of human serum Paraoxonase PON1

, 2003
Substrate analogues based on the parent compounds paraoxon and phenyl acetate were tested on human serum paraoxonase (PON1) to explore the active site of the enzyme.
Akhtar, Mahmoud, Biggadike, K, Allemann, Rudolf, Gani, David, Bargota, Rakesh   +4 more
core   +1 more source

Associations of PON1 with Obesity Parameters at Ages 2 and 5.

, 2013
aPON1192 coded as number of Q alleles, 0, 1 or 2.bChildren were considered obese if their BMI was at or above 95th percentile of the 2000 CDC sex-specific BMI-for-age growth charts.cUsing a Bonferonni correction for multiple testing (5 tests per model ...
Kim Harley (409719), Brenda Eskenazi (27323), Nina Holland (409720), Karen Huen (207307), Kenneth Beckman (73447)   +4 more
core   +1 more source

The importance of paraoxonase 1 activity in chronic kidney disease

Renal Failure
Paraoxonase 1 (PON1) is one of the most significant antioxidative enzymes associated with high-density lipoprotein (HDL). It has been proved that is involved in the pathogenesis of many diseases including chronic kidney disease (CKD).
Elisabeth C. Samouilidou, Augustina Liaouri, Vassilis Kostopoulos, Dimitris Nikas, Eirini Grapsa   +4 more
doaj   +1 more source

Human serum paraoxonase (PON1) activity in acute organophosphorous insecticide poisoning

, 2003
40th Annual Meeting of the International-Association-of-Forensic-Toxicologists -- AUG 26-30, 2002 -- PARIS, FRANCEHuman serum paraoxonase (PON1) and perhaps other mammalian paraoxonases catalyzes the hydrolysis of certain organophosphorus (OP ...
Solak, I, Ege, B, Ozturk, P, Moral, AR, Akgur, SA   +4 more
core   +1 more source

Paraoxonase 1 Phenotype and Paraoxonase Activity in Asthmatic Patients

Iranian Journal of Allergy, Asthma and Immunology, 2015
Oxidative stress is involved in the pathogenesis of asthma. Paraoxonase 1 (PON1) and arylesterase are esterase enzymes displaying antioxidant characteristics.
Nurhan Sarioglu, Adnan Adil Hismiogullari, Fuat Erel, Dudu Demir, Nahit Gencer   +4 more
doaj  

Decreased PON1 activity as a biological marker for depressive disorders: a narrative review

Journal of Affective Disorders Reports
Background: This study conducts a narrative review to summarize evidence regarding changes in serum/plasma paraoxonase 1 (PON1) activity in patients with major depressive disorder (MDD) or other depressive disorders and assess their possible marker value.
Oleg A. Levada, Oleksandra S. Troian
doaj   +1 more source

Association of a protective paraoxonase 1 (PON1) polymorphism in Parkinson's disease

, 2012
Pesticide exposure has been suggested to increase the risk to develop Parkinson's disease (PD). The arylesterase paraoxonase 1 (PON1) is mainly expressed in the liver and hydrolyzes organophosphates such as pesticides. The polymorphism Leu54Met (rs854560)
Anvret, M., Nissbrandt, Hans,, Westerlund, M., Håkansson, Anna,, Dizdar (Dizdar Segrell), Nil,, Söderkvist, Peter,, Soderkvist, P., Belin, A. C., Westerlund, Marie,, Anvret, A., Ran, C., Ran, Caroline,, Ahmadi, Ahmad,, Galter, D., Sydow, O., Willows, T., Dizdar, N., Belin, Andrea Carmine,, Willows, Thomas,, Sydow, Olof,, Paddock, Silvia,, Paddock, S., Ahmadi, A., Anvret, Anna,, Galter, Dagmar,, Anvret, Maria,, Belin, AC, Hakansson, A, Anvret, A, Ran, C,, Westerlund, M,, Dizdar, N, Soderkvist, P, Paddock, S, Nissbrandt, H, Ahmadi, A   +35 more
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Paraoxonase (PON1): from toxicology to cardiovascular medicine

, 2005
Paraoxonase (PON1) is a liver and plasma enzyme most studied because of its ability to hydrolyze the active metabolites of several organophosphorus insecticides.
C. E. Furlong, T. B. Cole, COSTA, Lucio Guido   +2 more
core  

Single nucleotide polymorphisms in PON1 gene and their relation with PON1 activity in Vokkaliga population of Mysore, South India

, 2012
The cardio protective functions of HDL are attributed to the HDL-associated proteins like Paraoxonase 1 (PON1). PON1 is associated with HDL through a N-terminal signal peptide. HDL-associated PON1 alone is cardio protective.
D’Souza, C. J. M., Cletus J. M. D’Souza, Frank, Elizabeth A., Jyothi, M., Jyothi Mallaiah, Rajashekara Reddy Ravuri, Elizabeth A. Frank, Ravuri, Rajashekara Reddy   +7 more
core   +1 more source