Results 131 to 140 of about 16,258 (219)

Somatic Gene Therapy in the Prevention of Toxic Effects of Organophosphate Agents

Вестник войск РХБ защиты
Medical intervention in poisoning by organophosphate toxic agents (OPA) using atropine sulfate, 2-pyridinaldoxymethyl chloride (2-PAM), diazepam and other similar drugs can prevent the fatal outcome of poisoning.
J. Lakota
doaj   +1 more source

The Regulatory Variant -108C/T in the Promoter of Paraoxonase 1 (PON1) Gene has a More Important Role in Regulating PON1 Activity Compared to rs3735590 in 3ʹ-UTR in Patients with Coronary Artery Disease

Advanced Biomedical Research
Background: This study aimed to assess the serum activity of paraoxonase 1 (PON1) in patients with coronary artery disease (CAD) based on two genetic variants including the -108C/T variant in the promoter region and the rs3735590 variant in the binding ...
Mehryar Zargari, Negar Maadi, Maysam Rezapour, Abouzar Bagheri, Samane Fallahpour, Mani Nosrati, Abdolkarim Mahrooz   +6 more
doaj   +1 more source

PON1 arylesterase activity in the healthy subjects and the ACS patients and based on their PON1 55 genotype.

, 2015
The PON1 L55M genotype was determined by RT-PCR. PON1 arylesterase activity was measured by the increase in absorbance at 270 using phenylacetate as a substrate.
Pamela Camponova (779670), Abdelghani Bounafaa (779663), Abdelouahed Khalil (3826456), Abdelkhalid Essamadi (779673), Hicham Berrougui (779664), Najoua Yamoul (779671), Abderrahmane Moujahid (779668), Abdallah Bagri (779667), Olivier Kamtchueng Simo (779672), Noreddine Ghalim (779665), Souad Ikhlef (779669), Boubker Nasser (779666)   +11 more
core   +1 more source

Polymorfismus allel lidské paraoxonasy (PON1) a hemodialýza

, 2008
Allelický polymorfismus lidské paroxonasy a hemodialýza Renata Dvořáková ABSTRAKT Nemocní léčení hemodialýzou (HD) mají vysoké riziko koronárního onemocnění. Lidská paraoxonasa (PON1, EC 3.1.8.1) je enzym asociovaný s lipoproteinem o vysoké hustotě (HDL),
Dvořáková, Renata
core  

Genetic and temporal determinants of pesticide sensitivity: role of paraoxonase (PON1)

, 2000
Susceptibility to organophosphorus (OP) insecticides and nerve agents is strongly influenced by genetic and developmental factors. A number of organophosphorothioate insecticides are detoxified in part via a two-step pathway involving bioactivation of ...
Li, W. F, Richter, R. J, Costa, L. G., Shih, D. M, Alleva, E, Furlong, C. E, Lusis, A. J   +6 more
core  

CRISPR/dCas9-induced upregulation of endogenous apolipoprotein A1 and paraoxonase 1 genes reduces the aortic lipid deposits in apoE^-/- mice. [PDF]

Mol Biomed
Toma L, Barbălată T, Hărătău JIC, Sanda GM, Fuior EV, Fenyo IM, Niculescu LŞ, Dăian LM, Sasson S, Sima AV, Stancu CS.   +10 more
europepmc   +1 more source

Reduced Serum PON1 Lactonase Activity Is Associated with Mild Cognitive Impairment and Mixed Dementia. [PDF]

Antioxidants (Basel)
Riccetti R, Trentini A, Mola G, Brombo G, di Paola DF, Castellazzi M, Candeloro R, Manfrinato MC, Zuliani G, Cervellati C.   +9 more
europepmc   +1 more source

Role of polyphenols and polyphenol-rich foods in the modulation of PON1 activity and expression.

Journal of Nutritional Biochemistry, 2017
D. Martini, C. Del Bo', M. Porrini, S. Ciappellano, P. Riso   +4 more
semanticscholar   +1 more source

Association of <i>PON1</i> Haplotypes (Q192R and L55M) with the Severity of Coronary Atherosclerosis. [PDF]

Int J Mol Sci
Rychlik-Sych M, Barańska M, Dudarewicz M, Owczarek J.   +3 more
europepmc   +1 more source

Occupational Organophosphorus Pesticide Exposure and Metabolic Syndrome: Implications of PPARγ. [PDF]

Toxics
Sakr S, Eldaly MM, Elshamy RA, Almadani N, Nofal HA, Hammad SA, Eldesoqui M, Soliman WI.   +7 more
europepmc   +1 more source