Results 151 to 160 of about 6,713 (180)

Longitudinal changes in PON1 activities, PON1 phenotype distribution and oxidative status throughout normal pregnancy

Reproductive Toxicology, 2012
The purpose of the present study was to determine changes in plasma paraoxonase-1 activity (an indicator of paraoxonase phenotype) throughout normal pregnancy and its relationship with maternal oxidative stress status. The frequencies of the paraoxonase-1 phenotype in the studied population were determined using a two-substrate (paraoxon/diazoxon ...
Stefanović, Aleksandra, Ardalić, Daniela, Kotur-Stevuljević, Jelena, Vujović, Ana, Spasić, Slavica, Spasojević-Kalimanovska, Vesna, Jelić-Ivanović, Zorana, Mandić-Marković, Vesna, Miković, Željko, Cerović, Nikola   +9 more
openaire   +4 more sources

?????????????????????????? ?????????????????? ???? ?????????????? PON1 ?? APM1 ?? ???????????? ?????????????? ?????????????????? ????????????????

2021
?????????????? ???????????????????? ?? 109 ?????????????????????? ???????????????? ?????????????? ??. ????????????????. ?????????????? ???????????? Q ???????? ???????????????????????? ?????????? ???????????????? ?????????????? ???????????????????? 0,67; ?????????????? ???????????? R ??? 0,33. ?????????????????????????? ?????????????????? ??????????????
openaire   +1 more source

The Relationship between PON1 Phenotype and PON1-192 Genotype in Detoxification of Three Oxons by Human Liver

Drug Metabolism and Disposition, 2007
Phosphorothioate pesticides (OP) such as diazinon, chlorpyrifos, and parathion are activated to highly toxic oxon metabolites by the cytochromes P450 (P450s), mainly in the liver. Simultaneously, the P450s catalyze detoxification of OP to nontoxic dearylated metabolites.
Mutch E, Daly AK, Williams FM
openaire   +3 more sources

???????????????????? ???????????????? ?? ?????????? ?????????????????? ????????: ???????????????? ???????????????????????????? ?????????????????????????? ???? ???????????? PON1 ???? FTO

2013
Shown no statistically significant differences of functional polymorphisms of genes PON1 and FTO in the determination of the risk of obesity in school-age children. The presence of abnormally burdened alleles does not significantly affect the distribution of body fat mass for healthy children, but there is direct strong correlation between neck ...
openaire   +1 more source

Paraoxonase (PON1) Gene Polymorphisms

2004
COSTA, Lucio Guido, FURLONG C. E.
openaire   +3 more sources

Paraoxonase‐1 (PON1) Status Analysis Using Non‐Organophosphate Substrates

Current Protocols, 2021
Lucio G Costa, Judit Marsillach, Clement Furlong   +2 more
exaly  

PON1 Structure

2002
Denis Josse, Patrick Masson, Cynthia Bartels, Oksana Lockridge   +3 more
openaire   +1 more source

PON1 Polymorphisms

2002
Victoria H. Brophy, Gail P. Jarvik, Clement E. Furlong   +2 more
openaire   +1 more source

Serum paraoxonase (PON1) and its interactions with HDL: Relationship between PON1 and oxidative stress

2010
PON1 is a high density lipoprotein (HDL)-associated serum enzyme. Its primary function is to degrade commonly used insecticides and nerve gases. PON1 is found to be more effective than lecithin:cholesterol acyltransferase (LCAT) or apoA-I in protecting low density lipoproteins (LDL) against oxidation.
Vekić, Jelena, Kotur-Stevuljević, Jelena, Zeljković, Aleksandra, Stefanović, Aleksandra, Jelić-Ivanović, Zorana, Spasić, S, Spasojević-Kalimanovska, Vesna   +6 more
openaire   +2 more sources

Paraoxonase (PON1) Enzyme and Polymorphisms

2014
Paraoxonase enzyme has initially been identified as a protective barrier against organophosphorus poisoning. In the recent years, a wide range of investigations were conducted on this enzyme and the knowledge about its functions and the etiopathogenetic role in some diseases has been clarified in depth.
KOÇ, Hatice Bige, KAÇAR, Yasemin
openaire   +1 more source