Results 181 to 190 of about 16,258 (219)

Chlorpyrifos and Chlorpyrifos-Oxon: A Widening Spectrum of Toxicity. [PDF]

Int J Mol Sci
Kalenik S, Zaczek A, Rodacka A.
europepmc   +1 more source

Exploring Influencing Factors Including CYP2C19 Genotypes, and Developing a Machine Learning-Based Predictive Model for Clopidogrel Resistance in Chinese Patients with Ischemic Stroke. [PDF]

Int J Gen Med
Xu B, Gu L, Lin G, Ni H, Shi H, Chen B.
europepmc   +1 more source

Exposure to Heavy Metals Arsenic, Cadmium and Lead Exacerbates Carcinogenic and Noncarcinogenic Health Risks Among Diabetic and Hypertensive Patients. [PDF]

J Toxicol
Mbebwoh FZ, Kum MJT, Aphrodite CT, Antoine KS, Suh FC, Pascal MTF, Edouard NA.   +6 more
europepmc   +1 more source

Developmental Changes in PON1 Enzyme Activity in Young Children and Effects of PON1 Polymorphisms [PDF]

Environmental Health Perspectives, 2009
BACKGROUND: Paraoxonase 1 (PON1) is an enzyme that detoxifies activated organophosphorus pesticides (OPs) and is also involved in oxidative stress pathways.
Asa Bradman, Kim Harley, Brenda Eskenazi   +2 more
exaly   +2 more sources

Paraoxonase-1 (PON1) Status Analysis Using Non-Organophosphate Substrates [PDF]

Current Protocols, 2021
Human paraoxonase-1 (PON1) is a high-density lipoprotein-associated enzyme with antioxidant, anti-inflammatory, and antiapoptotic roles. The ability of PON1 to hydrolyze specific organophosphate (OP) compounds and prevent accumulation of oxidized lipids ...
Lucio G. Costa, Judit Marsillach, Clement E Furlong   +2 more
exaly   +2 more sources

The effect of HDL-bound and free PON1 on copper-induced LDL oxidation.

Chemico-Biological Interactions, 2016
Oxidative modification of LDL plays an important role in the development of atherosclerosis. High density lipoprotein (HDL) confers protection against atherosclerosis and the antioxidative properties of paraoxonase 1 (PON1) has been suggested to ...
Ahmet Tugrul Bayrak, T. Bayrak, E. Bodur, K. Kilinç, E. Demirpençe   +4 more
semanticscholar   +2 more sources

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Importance of paraoxonase 1 (PON1) as an antioxidant and antiatherogenic enzyme in the cardiovascular complications of type 2 diabetes: Genotypic and phenotypic evaluation.

Diabetes Research and Clinical Practice, 2020
Oxidant-antioxidant imbalance is involved in the etiology of different diseases, including cardiovascular diseases (CVDs), liver disorders, kidney diseases, cancers and diabetes mellitus.
Y. Shokri, Atena Variji, Mani Nosrati, Abbas Khonakdar-Tarsi, Anvarsadat Kianmehr, Z. Kashi, A. Bahar, A. Bagheri, A. Mahrooz   +8 more
semanticscholar   +1 more source

The epigenetic regulation of paraoxonase 1 (PON1) as an important enzyme in HDL function: The missing link between environmental and genetic regulation.

Clinical Biochemistry, 2019
BACKGROUND Paraoxonase 1 (PON1) is an important antiatherogenic and antioxidant enzyme in the circulation that has been associated with adverse health outcomes particularly cardiovascular disease (CVD) and other metabolic disorders.
A. Mahrooz, M. Mackness, A. Bagheri, M. Ghaffari-Cherati, Parisa Masoumi   +4 more
semanticscholar   +1 more source

The combined utility of myeloperoxidase (MPO) and paraoxonase 1 (PON1) as two important HDL-associated enzymes in coronary artery disease: Which has a stronger predictive role?

Atherosclerosis, 2019
BACKGROUND AND AIMS Serum paraoxonase 1 (PON1) and myeloperoxidase (MPO) are HDL-associated enzymes that contribute significantly to the formation of dysfunctional HDL.
Atena Variji, Y. Shokri, S. Fallahpour, M. Zargari, B. Bagheri, S. Abediankenari, A. Alizadeh, A. Mahrooz   +7 more
semanticscholar   +1 more source