Results 231 to 240 of about 121,997 (290)

Development of micro-fibrous solid dispersions of poorly water-soluble drugs in sucrose using temperature-controlled centrifugal spinning.

Eur J Pharm Biopharm, 2016
Marano S, Barker SA, Raimi-Abraham BT, Missaghi S, Rajabi-Siahboomi A, Craig DQM.   +5 more
europepmc   +1 more source

Magnetic Field Driven Microrobot Based on Hydrogels

Advanced Robotics Research, EarlyView.
Hydrogel‐based magnetic microrobots synergize remote magnetic control with the biocompatibility of flexible hydrogels, emerging as promising tools for minimally invasive biomedicine. This enables remotely controllable, untethered navigation within complex biological microenvironments.
Juncai Song, Yubing Guo
wiley   +1 more source

Optimization design of solution preparation methods of three poorly soluble drugs of clinical use in infusions on orthogonal test and evaluation of stability study. [PDF]

Biochem Biophys Rep
Jiang D, Fang D, Wang Z, Cun H, Fang B, Chen F.   +5 more
europepmc   +1 more source

Rational Design of Optical Single‐Walled Carbon Nanotube‐Based Nanosensors with Biological Recognition Elements

Advanced Sensor Research, EarlyView.
This Review focuses on assessing and providing perspective on the field of rationally‐designed optical sensors constructed with single‐walled carbon nanotubes. The literature is reviewed and evaluated for SWCNT‐based sensors constructed with biomolecular recognition elements, including proteins, peptides, and oligonucleotides, as well as their methods ...
Amelia K. Ryan, Atara Israel, Maria Celina Stefoni, Catarina Ferraz, Ryan M. Williams   +4 more
wiley   +1 more source

Evaluating the Impact of Intestinal Bile Salts on Drug Absorption Using PBPK Modeling: Case Studies With Efavirenz, Cinnarizine, and Posaconazole. [PDF]

CPT Pharmacometrics Syst Pharmacol
Al-Amiry Santos LG, Polak S, Yeo KR.
europepmc   +1 more source

Theoretical View: Thermodynamics of the Saturation Dissolution of a Molecular (Solid) Dispersion of a Hydrophobic Molecule and Polymeric Surfactant in an Aqueous Solution. [PDF]

Int J Mol Sci
Poša M.
europepmc   +1 more source

Drug Delivery System for the Anticancer Drug Paclitaxel Using Lipocalin-Type Prostaglandin D Synthase Conjugated to a Tumor-Targeting Peptide. [PDF]

ACS Omega
Furuta K, Nakatsuji M, Yoshida H, Okubo R, Nishide K, Yamamura T, Inui T.   +6 more
europepmc   +1 more source

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Nanoprecipitation for Poorly Water-Soluble Drugs

Current Drug Metabolism, 2018
More than 60% of the active pharmaceutical ingredients, which are classified as Biopharmaceutics Classification System class II. The limited solubility of these drug may lead to low therapeutic effects.Nanoprecipitation presents some advantages because it is a straightforward method with low-cost equipment that is easy to scale up.However, there are ...
Tuong N G, Nguyen, Van-Thanh, Tran, Wei, Duan, Phuong H L, Tran, Thao T D, Tran   +4 more
openaire   +2 more sources

Hydrotropic Solubilization of Poorly Water-Soluble Drugs

Journal of Pharmaceutical Sciences, 2010
The solubilizing ability of two aromatic hydrotropes, N,N-diethylnicotinamide (DENA) and N,N-dimethylbenzamide (DMBA), was investigated using a set of 13 poorly soluble, structurally diverse drugs. The number of aromatic rings in the solute molecule has a very strong effect on the solubility enhancement produced by either hydrotrope.
Ji Young, Kim, Sungwon, Kim, Michelle, Papp, Kinam, Park, Rodolfo, Pinal   +4 more
openaire   +2 more sources

Drug Nanoparticles: Formulating Poorly Water-Soluble Compounds

Toxicologic Pathology, 2008
More than 40% of compounds identified through combinatorial screening programs are poorly soluble in water. These molecules are difficult to formulate using conventional approaches and are associated with innumerable formulation-related performance issues.
Elaine M, Merisko-Liversidge, Gary G, Liversidge   +1 more
openaire   +2 more sources