Results 1 to 10 of about 6,377,716 (133)

The role of cell cycle-related genes in the tumorigenesis of adrenal and thyroid neuroendocrine tumors

Heliyon
The molecular mechanisms underlying adrenal and thyroid neuroendocrine tumors, including their tumorigenesis, progression, and metastasis, involve unique pathways regulating cell cycle progression.
Ekaterina Filipovich, Ekaterina Gorodkova, Anastasia Shcherbakova, Walaa Asaad, Sergey Popov, Galina Melnichenko, Natalya Mokrysheva, Marina Utkina   +7 more
doaj   +1 more source

Genetic diversity and conservation in Bromeliaceae based on SSR markers [PDF]

Genetics and Molecular Biology
Bromeliaceae has been used as a model Neotropical group to study evolutionary and diversification processes. Moreover, since large parts of the Neotropics are under anthropogenic pressure, a high percentage of possibly threatened species occurs.
Milene Ferreira Barcellos, Laís Mara Santana Costa, Fernanda Bered   +2 more
doaj   +1 more source

Unraveling the Complexity of the Ne/Nc Ratio for Conservation of Large and Widespread Pelagic Fish Species: Current Status and Challenges

Evolutionary Applications
Estimating and understanding the ratio between effective population size (Ne) and census population size (Nc) are pivotal in the conservation of large marine pelagic fish species, including bony fish such as tunas and cartilaginous fish such as sharks ...
Chrystelle Delord, Sophie Arnaud‐Haond, Agostino Leone, Jonathan Rolland, Natacha Nikolic   +4 more
doaj   +1 more source

Faster model-based estimation of ancestry proportions

Peer Community Journal
Ancestry estimation from genotype data in unrelated individuals has become an essential tool in population and medical genetics to understand demographic population histories and to model or correct for population structure.
Santander, Cindy G., Refoyo Martinez, Alba, Meisner, Jonas   +2 more
doaj   +1 more source

Exploring a Pool‐seq‐only approach for gaining population genomic insights in nonmodel species

Ecology and Evolution, 2019
Developing genomic insights is challenging in nonmodel species for which resources are often scarce and prohibitively costly. Here, we explore the potential of a recently established approach using Pool‐seq data to generate a de novo genome assembly for ...
Sara Kurland, Christopher W. Wheat, Maria de laPaz Celorio Mancera, Verena E. Kutschera, Jason Hill, Anastasia Andersson, Carl‐Johan Rubin, Leif Andersson, Nils Ryman, Linda Laikre   +9 more
doaj   +1 more source

Exploring penetrance of clinically relevant variants in over 800,000 humans from the Genome Aggregation Database

Nature Communications
Incomplete penetrance, or absence of disease phenotype in an individual with a disease-associated variant, is a major challenge in variant interpretation.
Sanna Gudmundsson, Moriel Singer-Berk, Sarah L. Stenton, Julia K. Goodrich, Michael W. Wilson, Jonah Einson, Nicholas A. Watts, Genome Aggregation Database Consortium, Tuuli Lappalainen, Heidi L. Rehm, Daniel G. MacArthur, Anne O’Donnell-Luria   +11 more
doaj   +1 more source

Improved allele frequencies in gnomAD through local ancestry inference

Nature Communications
The Genome Aggregation Database (gnomAD) is a foundational resource for allele frequency data, widely used in genomic research and clinical interpretation.
Pragati Kore, Michael W. Wilson, Grace Tiao, Katherine Chao, Philip W. Darnowsky, Nicholas A. Watts, Jessica Honorato Mauer, Samantha M. Baxter, Genome Aggregation Database Consortium, Heidi L. Rehm, Mark J. Daly, Konrad J. Karczewski, Elizabeth G. Atkinson   +12 more
doaj   +1 more source

Genetic Sex and Origin Identification Suggests Differential Migration of Male and Female Atlantic Bluefin Tuna (Thunnus thynnus) in the Northeast Atlantic

Evolutionary Applications
Knowledge about sex‐specific difference in life‐history traits—like growth, mortality, or behavior—is of key importance for management and conservation as these parameters are essential for predictive modeling of population sustainability.
Einar Eg Nielsen, Kim Birnie‐Gauvin, Henrik Baktoft, Haritz Arrizabalaga, Tomas Brodin, Massimiliano Cardinale, Michele Casini, Gustav Helström, Teunis Jansen, Anders Koed, Petter Lundberg, Brian R. MacKenzie, Antonio Medina, Søren Post, Naiara Rodriguez‐Ezpeleta, Andreas Sundelöf, José Luis Varela, Kim Aarestrup   +17 more
doaj   +1 more source

Genetika Populasi dan Strategi Konservasi Badak Jawa (Rhinoceros sondaicus Desmarest 1822) (Population Genetics of Javan Rhino (Rhinoceros sondaicus Desmarest 1822) and It’s Conservation Strategy)

Jurnal Manajemen Hutan Tropika, 2011
Javan rhino (Rhinoceros sondaicus Desmarest 1822) of which spread is limited in Indonesia and Vietnam is the rarest species among 5 species of rhino in the world. Without appropriate and long-term well organized management action, the population of javan
U Mamat Rahmat
doaj   +3 more sources

A Comparative Meta‐Analysis on the Association of lncRNAs MALAT1, HOTAIR, and AFAP1‐AS1 With the Risk of Developing Lymph Node Metastasis in Lung Cancer

Cancer Reports
Background Numerous studies have demonstrated the significance of long noncoding RNA (lncRNA) in the development of cancer metastasis. The expression levels of many lncRNAs are elevated in metastatic lung cancer patients compared to non‐metastatic lung ...
Anha Tasnim, Afra Anjum Sumaiya, Abdullah Al Noman, Anika Tahsin, Abdullah Al Saba, Rubaiat Ahmed, Tahirah Yasmin, A. H. M. Nurun Nabi   +7 more
doaj   +1 more source