Results 1 to 10 of about 1,354,958 (326)

The evolution of moment generating functions for the Wright Fisher model of population genetics

, 2014
We derive and apply a partial differential equation for the moment generating function of the Wright-Fisher model of population ...
Hofrichter, Julian, Jost, Juergen, Tran, Tat Dat   +2 more
core   +1 more source

Exploring the effects of ecological parameters on the spatial structure of genetic tree sequences

Peer Community Journal
Geographic space is a fundamental dimension of evolutionary change, determining how individuals disperse and interact with each other. Consequently, space has an important influence on the structure of genealogies and the distribution of genetic variants
Ianni-Ravn, Mariadaria K., Petr, Martin, Racimo, Fernando   +2 more
doaj   +1 more source

Epistatic regulation of growth in Atlantic salmon revealed: a QTL study performed on the domesticated-wild interface

BMC Genetics, 2020
Background Quantitative traits are typically considered to be under additive genetic control. Although there are indications that non-additive factors have the potential to contribute to trait variation, experimental demonstration remains scarce.
Francois Besnier, Monica F. Solberg, Alison C. Harvey, Gary R. Carvalho, Dorte Bekkevold, Martin I. Taylor, Simon Creer, Einar E. Nielsen, Øystein Skaala, Fernando Ayllon, Geir Dahle, Kevin A. Glover   +11 more
doaj   +1 more source

Using neutral cline decay to estimate contemporary dispersal: a generic tool and its application to a major crop pathogen [PDF]

, 2013
Dispersal is a key parameter of adaptation, invasion and persistence. Yet standard population genetics inference methods hardly distinguish it from drift and many species cannot be studied by direct mark-recapture methods.
Amil, Barton, Barton, Barton, Barton, Barton, Broquet, Brown, Burt, Carlier, Chen, Daguin, Dieckmann, Endler, Fisher, Gay, Giraud, Goudet, Guillot, Guillot, Halkett, Jones, Lapeyre de Bellaire, Lebreton, Lenormand, Lenormand, Lenormand, Lenormand, Lockwood, McCartney, McDonald, Mourichon, Neu, Pennisi, Rieux, Rieux, Robert, Ronce, Rousset, Rousset, Rousset, Saccheri, Sackett, Slatkin, Storey, Turelli, Zapater   +46 more
core   +1 more source

Little evidence of inbreeding depression for birth mass, survival and growth in Antarctic fur seal pups

Scientific Reports
Inbreeding depression, the loss of offspring fitness due to consanguineous mating, is generally detrimental for individual performance and population viability.
A. J. Paijmans, A. L. Berthelsen, R. Nagel, F. Christaller, N. Kröcker, J. Forcada, J. I. Hoffman   +6 more
doaj   +1 more source

Growth, competition and cooperation in spatial population genetics [PDF]

, 2012
We study an individual based model describing competition in space between two different alleles. Although the model is similar in spirit to classic models of spatial population genetics such as the stepping stone model, here however space is continuous ...
Allstadt, Barton, Benzi, Berti, Birch, Cencini, Crow, D.R. Nelson, Doering, D’Ovidio, F. Toschi, Fisher, Frey, Gardiner, Hallatschek, Hernandez-Garcia, Kimura, Kimura, Kolmogorov, Korolev, Korolev, Korolev, Law, M.H. Jensen, Neufeld, Neuhauser, Odor, O’Malley, O’Malley, P. Perlekar, Perlekar, Perlekar, Pigolotti, Pringle, R. Benzi, Risken, S. Pigolotti, Smith, Tel, Vlad, Wright   +40 more
core   +3 more sources

Population genetics and GWAS: A primer. [PDF]

PLoS Biology, 2018
This primer provides some background to help non-specialists understand a new theoretical evolutionary genetics study that helps explain why thousands of variants of small effect contribute to complex traits.
Greg Gibson
doaj   +1 more source

Genes Classical And Genes Developmental: The Different Uses Of The Gene In Evolutionary Synthesis [PDF]

, 2000
Dobzhansky (1964) stated that “Nothing in biology makes sense except in the light of evolution,” and the function of the gene is no exception. The use of genes in population genetics and developmental genetics differs significantly.
Gilbert, Scott F.
core   +3 more sources

Genetics and context for precision health in Greater Boston

Nature Communications
Mass General Brigham, an integrated healthcare system based in the Greater Boston area of Massachusetts, annually serves 1.5 million patients. We established the Mass General Brigham Biobank (MGBB), currently encompassing 142,238 participants, to unravel
Satoshi Koyama, Ying Wang, Kaavya Paruchuri, Md Mesbah Uddin, So Mi J. Cho, Sarah M. Urbut, Yang Sui, Akl C. Fahed, Himani Kamineni, Sara Haidermota, Whitney E. Hornsby, Robert C. Green, Mark J. Daly, Benjamin M. Neale, Patrick T. Ellinor, Jordan W. Smoller, Susan A. Slaugenhaupt, Matthew S. Lebo, Elizabeth W. Karlson, Alicia R. Martin, Pradeep Natarajan   +20 more
doaj   +1 more source

Coalescence 2.0: a multiple branching of recent theoretical developments and their applications [PDF]

, 2014
Population genetics theory has laid the foundations for genomics analyses including the recent burst in genome scans for selection and statistical inference of past demographic events in many prokaryote, animal and plant species.
Lemaire, Christophe, Tellier, Aurelien
core   +5 more sources