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Population genetics in microchannels [PDF]
Proceedings of the National Academy of Sciences, 2021 Spatial constraints such as rigid barriers affect the dynamics of cell populations, potentially altering the course of natural evolution. In this paper, we study the population genetics of Escherichia coli proliferating in microchannels with open ends ...
Koldaeva, Anzhelika +3 more
core +5 more sources
Molecular Population Genetics [PDF]
Genetics, 2017 Molecular population genetics aims to explain genetic variation and molecular evolution from population genetics principles. The field was born 50 years ago with the first measures of genetic variation in allozyme loci, continued with the nucleotide ...
Sònia Casillas, A. Barbadilla
semanticscholar +3 more sources
Definitions, 2020 There are thousands of ebooks available to download legally – either because their copyright has expired, or because their authors have chosen to release them without charge.
Brian Charlesworth, Jeffrey D. Jensen
semanticscholar +3 more sources
Genetic draft, selective interference, and population genetics of rapid adaptation [PDF]
Annual Review of Ecology, Evolution, and Systematics Vol. 44:
195-215, 2013, 2013 To learn about the past from a sample of genomic sequences, one needs to understand how evolutionary processes shape genetic diversity. Most population genetic inference is based on frameworks assuming adaptive evolution is rare. But if positive selection operates on many loci simultaneously, as has recently been suggested for many species including ...
Neher, Richard A.
arxiv +4 more sources
Archetypal Analysis for population genetics. [PDF]
PLoS Computational Biology, 2022 The estimation of genetic clusters using genomic data has application from genome-wide association studies (GWAS) to demographic history to polygenic risk scores (PRS) and is expected to play an important role in the analyses of increasingly diverse ...
Julia Gimbernat-Mayol +4 more
doaj +2 more sources
Author Correction: Landscape of multi-nucleotide variants in 125,748 human exomes and 15,708 genomes
Nature Communications, 2021 A Correction to this paper has been published: https://doi.org/10.1038/s41467-021-21077-8.
Qingbo Wang +11 more
doaj +1 more source
Scientific Reports, 2022 Non-invasive prenatal testing (NIPT) to detect fetal aneuploidy by sequencing the cell-free DNA (cfDNA) in maternal plasma is being broadly adopted. To detect fetal aneuploidies from maternal plasma, where fetal DNA is mixed with far-larger amounts of ...
Giulio Genovese +7 more
doaj +1 more source
Information-Geometric Optimization with Natural Selection
Entropy, 2020 Evolutionary algorithms, inspired by natural evolution, aim to optimize difficult objective functions without computing derivatives. Here we detail the relationship between classical population genetics of quantitative traits and evolutionary ...
Jakub Otwinowski +2 more
doaj +1 more source
Spatial Population Genetics: It's About Time [PDF]
Annual Review of Ecology, Evolution and Systematics, 2019 Many important questions about the history and dynamics of organisms have a geographical component: How many are there, and where do they live? How do they move and interbreed across the landscape?
Gideon S. Bradburd, Peter L. Ralph
semanticscholar +1 more source