Results 21 to 30 of about 7,466,882 (388)
Population Genetics and Pharmacogenetics [PDF]
, 2007 Genome-wide association studies (GWAS) have been hugely successful in identifying thousands of genetic loci robustly associated with hundreds of disease and other human traits. Since the first GWAS publication in an endocrinology-related topic, obesity in 2007, these studies have very rapidly increased in size and productivity. In 2011, this chapter is
Ken K. Ong, Cathy Elks
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Inherited basis of visceral, abdominal subcutaneous and gluteofemoral fat depots
Nature Communications, 2022 The inherited basis of body fat distribution is not fully understood. Here, the authors use genetic data and MRI-derived measures of local adiposity to highlight fat depot-specific genetic architecture with implications for cardiometabolic health.
Saaket Agrawal +15 more
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Population Genetics and Pharmacogenetics [PDF]
, 2005 The highlight for 2005/6 in population genetics was undoubtedly the publication of HapMap, a freely available public resource nearly of all common (>5% minor allele frequency) genetic differences in humans. Compared to the estimated 10 million single nucleotide polymorphisms (SNP) that we all share, at the launch of HapMap in 2002 there were fewer than
Heude, Barbara, Ong, Ken
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Growth, competition and cooperation in spatial population genetics [PDF]
, 2012 We study an individual based model describing competition in space between two different alleles. Although the model is similar in spirit to classic models of spatial population genetics such as the stepping stone model, here however space is continuous ...
Allstadt +40 more
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Neutral genomic signatures of host-parasite coevolution
BMC Evolutionary Biology, 2019 Background Coevolution is a selective process of reciprocal adaptation in hosts and parasites or in mutualistic symbionts. Classic population genetics theory predicts the signatures of selection at the interacting loci of both species, but not the ...
Daniel živković +4 more
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The Pennsylvania grotto sculpin: population genetics [PDF]
Subterranean Biology, 2021 The Pennsylvania grotto sculpin is known from just two caves of the Nippenose Valley in central Pennsylvania, USA. They exhibit emergent troglobitic morphological traits and are the second northern-most cave adapted fish in the world.
Luis Espinasa +2 more
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Genes Classical And Genes Developmental: The Different Uses Of The Gene In Evolutionary Synthesis [PDF]
, 2000 Dobzhansky (1964) stated that “Nothing in biology makes sense except in the light of evolution,” and the function of the gene is no exception. The use of genes in population genetics and developmental genetics differs significantly.
Gilbert, Scott F.
core +3 more sources
pegas: an R package for population genetics with an integrated-modular approach
Bioinform., 2010 SUMMARY pegas (Population and Evolutionary Genetics Analysis System) is a new package for the analysis of population genetic data. It is written in R and is integrated with two other existing R packages (ape and adegenet).
E. Paradis
semanticscholar +1 more source
The Genetic Structure of Populations. [PDF]
The Journal of Ecology, 1975 The genetic structure of populations , The genetic structure of populations , مرکز فناوری اطلاعات و اطلاع رسانی ...
Brian Charlesworth +3 more
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BMC Biology, 2022 Background Fishes are the one of the most diverse groups of animals with respect to their modes of sex determination, providing unique models for uncovering the evolutionary and molecular mechanisms underlying sex determination and reversal.
Le Wang +15 more
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