Results 101 to 110 of about 8,031,804 (248)

A haplotype-resolved draft genome of the European sardine (Sardina pilchardus) [PDF]

open access: yes, 2019
The European sardine (Sardina pilchardus Walbaum, 1792) is culturally and economically important throughout its distribution. Monitoring studies of sardine populations report an alarming decrease in stocks due to overfishing and environmental change ...
Canario, A.V.M.   +7 more
core   +1 more source

Population genetics meets cancer genomics [PDF]

open access: yesProceedings of the National Academy of Sciences, 2010
There is a broad consensus that genetic alterations of normal body cells are the basis of cancer progression. Throughout the lifetime of an individual, her or his cells have to divide often, which is associated with occasional genetic changes. Some of the changes lead to uncontrolled cell proliferation and, at later stages of cancer progression, to ...
openaire   +2 more sources

On the Population Dynamics of Junk: A Review on the Population Genomics of Transposable Elements

open access: yesGenes, 2019
Transposable elements (TEs) play an important role in shaping genomic organization and structure, and may cause dramatic changes in phenotypes. Despite the genetic load they may impose on their host and their importance in microevolutionary processes ...
Y. Bourgeois, S. Boissinot
semanticscholar   +1 more source

Status and potential of bacterial genomics for public health practice : a scoping review [PDF]

open access: yes, 2019
Background: Next-generation sequencing (NGS) is increasingly being translated into routine public health practice, affecting the surveillance and control of many pathogens.
Boon, Nele AM   +6 more
core   +2 more sources

Enabling Population and Quantitative Genomics

open access: yesGenetical Research, 2002
Dissection of quantitative traits to the nucleotide level requires phenotypic and genotypic analysis of traits on a genome scale. Here we discuss the set of community-wide genetic and molecular resources, including panels of specific types of inbred lines and high density resequencing and SNP detection, that will facilitate such studies.
Gibson, Greg, Mackay, Trudy F. C.
openaire   +3 more sources

Cohort Profile: East London Genes & Health (ELGH), a community-based population genomics and health study in British Bangladeshi and British Pakistani people

open access: yesInternational Journal of Epidemiology, 2019
Cohort Profile: East London Genes & Health (ELGH), a community-based population genomics and health study in British Bangladeshi and British Pakistani people Sarah Finer , Hilary C Martin, Ahsan Khan, Karen A Hunt, Beverley MacLaughlin, Zaheer Ahmed ...
S. Finer   +15 more
semanticscholar   +1 more source

2b-RAD genotyping for population genomic studies of Chagas disease vectors: Rhodnius ecuadoriensis in Ecuador [PDF]

open access: yes, 2017
Background: Rhodnius ecuadoriensis is the main triatomine vector of Chagas disease, American trypanosomiasis, in Southern Ecuador and Northern Peru.
Andersson, Björn   +10 more
core   +4 more sources

Population genomics and evolution of a fungal pathogen after releasing exotic strains to control insect pests for 20 years

open access: yesThe ISME Journal, 2020
Entomopathogenic fungi are one of the key regulators of insect populations in nature. Some species such as Beauveria bassiana with a wide host range have been developed as promising alternatives to chemical insecticides for the biocontrol of insect pests.
Lijuan Mei   +9 more
semanticscholar   +1 more source

XBP1 expression in pancreatic islet cells is associated with poor glycaemic control especially in young non-obese onset diabetes across ancestries

open access: yesCommunications Medicine
Background Individuals of South and East Asian ancestry have a higher risk of type 2 diabetes, often driven by insulin deficiency due to impaired beta-cell function.
Moneeza K. Siddiqui   +24 more
doaj   +1 more source

Genetical genomics dissection of cotton fiber quality [PDF]

open access: yes, 2008
Cotton fiber is a commodity of key economic importance in both developed and developing countries. The two cultivated species, Gossypium hirsutum and G. barbadense , are tetraploid (2n=1x= 52 . 2.3 Gb).
Jacobs, John   +2 more
core  

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