Results 111 to 120 of about 8,031,804 (248)

Population genomics from pool sequencing

open access: yesMolecular Ecology, 2013
AbstractNext generation sequencing of pooled samples is an effective approach for studies of variability and differentiation in populations. In this paper we provide a comprehensive set of estimators of the most common statistics in population genetics based on the frequency spectrum, namely the Watterson estimator , nucleotide pairwise diversity Π ...
Ferretti, Luca   +2 more
openaire   +3 more sources

Insights from Population Genomics to Enhance and Sustain Biological Control of Insect Pests

open access: yesInsects, 2020
Biological control—the use of organisms (e.g., nematodes, arthropods, bacteria, fungi, viruses) for the suppression of insect pest species—is a well-established, ecologically sound and economically profitable tactic for crop protection. This approach has
Arun Sethuraman   +3 more
semanticscholar   +1 more source

Differential Functional Constraints Cause Strain-Level Endemism in Polynucleobacter Populations. [PDF]

open access: yes, 2016
The adaptation of bacterial lineages to local environmental conditions creates the potential for broader genotypic diversity within a species, which can enable a species to dominate across ecological gradients because of niche flexibility.
Geeta Rijal   +8 more
core   +2 more sources

Characterising the phenotype and ‍outcomes of cascade-tested relatives of probands with ‍hypertrophic cardiomyopathy

open access: yesOpen Heart
Objectives Cascade-tested relatives of individuals with pathogenic genetic variants in sarcomere genes causing hypertrophic cardiomyopathy are recommended. Little is known about the outcomes in cascade-identified relatives.
Catherine Mcwilliam   +3 more
doaj   +1 more source

Population Genomics of Saccharomyces Yeasts

open access: yes, 2009
This thesis examines genome-wide polymorphisms amongst 20 strains of Saccharomyces paradoxus, a yeast strain which has recently emerged as a model organism for population genetic studies. Three major studies are included in this thesis. The first study
Tsai , Isheng Jason, Tsai , Isheng Jason
core   +1 more source

Highly Variable Genomic Landscape of Endogenous Retroviruses in the C57BL/6J Inbred Strain, Depending on Individual Mouse, Gender, Organ Type, and Organ Location. [PDF]

open access: yes, 2017
Transposable repetitive elements, named the "TREome," represent ~40% of the mouse genome. We postulate that the germ line genome undergoes temporal and spatial diversification into somatic genomes in conjunction with the TREome activity.
Cho, Kiho   +3 more
core   +2 more sources

Genomic selection in livestock populations

open access: yesGenetics Research, 2010
SummaryMost traits of economic importance in livestock are either quantitative or complex. Despite considerable efforts, there has been only limited success in identifying the polymorphisms that cause variation in these traits. Nevertheless, selection based on estimated breeding values (BVs), calculated from data on phenotypic performance and pedigree ...
Goddard, Michael E.   +2 more
openaire   +3 more sources

Population genomics of intrapatient HIV-1 evolution

open access: yeseLife, 2015
Many microbial populations rapidly adapt to changing environments with multiple variants competing for survival. To quantify such complex evolutionary dynamics in vivo, time resolved and genome wide data including rare variants are essential.
Fabio Zanini   +6 more
doaj   +1 more source

BMI variability and cardiovascular outcomes within clinical trial and real-world environments in type 2 diabetes: an IMI2 SOPHIA study

open access: yesCardiovascular Diabetology
Background BMI variability has been associated with increased cardiovascular disease risk in individuals with type 2 diabetes, however comparison between clinical studies and real-world observational evidence has been lacking.
Robert J. Massey   +8 more
doaj   +1 more source

A gene-derived SNP-based high resolution linkage map of carrot including the location of QTL conditioning root and leaf anthocyanin pigmentation [PDF]

open access: yes, 2014
Purple carrots accumulate large quantities of anthocyanins in their roots and leaves. These flavonoid pigments possess antioxidant activity and are implicated in providing health benefits.
Cavagnaro, Pablo Federico   +6 more
core   +2 more sources

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