Results 201 to 210 of about 16,226,702 (331)

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

Correction: Human impact on the recent population history of the elusive European wildcat inferred from whole genome data. [PDF]

open access: yesBMC Genomics, 2023
Nieto-Blázquez ME   +5 more
europepmc   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

open access: yesFEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz   +9 more
wiley   +1 more source

The ecological niche and population history shape mosquito population genetics on a group of three Caribbean islands. [PDF]

open access: yesParasit Vectors
Helleman P   +7 more
europepmc   +1 more source

Population history, genetic variation, and conservation status of European white elm (Ulmus laevis Pall.) in Poland. [PDF]

open access: yesAnn For Sci, 2022
Litkowiec M   +5 more
europepmc   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

The Population History of Domestic Sheep Revealed by Paleogenomes. [PDF]

open access: yesMol Biol Evol
Kaptan D   +38 more
europepmc   +1 more source

Human impact on the recent population history of the elusive European wildcat inferred from whole genome data. [PDF]

open access: yesBMC Genomics, 2022
Nieto-Blázquez ME   +5 more
europepmc   +1 more source

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