Results 201 to 210 of about 2,115,565 (309)

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

The Population History of Domestic Sheep Revealed by Paleogenomes. [PDF]

Mol Biol Evol
Kaptan D, Atağ G, Vural KB, Morell Miranda P, Akbaba A, Yüncü E, Buluktaev A, Abazari MF, Yorulmaz S, Kazancı DD, Küçükakdağ Doğu A, Çakan YG, Özbal R, Gerritsen F, De Cupere B, Duru R, Umurtak G, Arbuckle BS, Baird D, Çevik Ö, Bıçakçı E, Gündem CY, Pişkin E, Hachem L, Canpolat K, Fakhari Z, Ochir-Goryaeva M, Kukanova V, Valipour HR, Hoseinzadeh J, Küçük Baloğlu F, Götherström A, Hadjisterkotis E, Grange T, Geigl EM, Togan İZ, Günther T, Somel M, Özer F.   +38 more
europepmc   +1 more source

Population history, genetic variation, and conservation status of European white elm (Ulmus laevis Pall.) in Poland. [PDF]

Ann For Sci, 2022
Litkowiec M, Chudzińska M, Pasławska A, Pałucka M, Kozioł C, Lewandowski A.   +5 more
europepmc   +1 more source

The ‘ins and outs’ of work – diversity or homogeneity in New Zealand women’s employment patterns?

, 2005
New Zealand has experienced sustained increases in women’s labour force participation since the post-war period. The Census of Population and Dwellings and the Household Labour Force Survey provide aggregate-level insights into labour force behaviour ...
Hillcoat-Nallétamby, Sarah, Baxendine, Sandra   +1 more
core  

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

The ecological niche and population history shape mosquito population genetics on a group of three Caribbean islands. [PDF]

Parasit Vectors
Helleman P, Schrama M, Trimbos KB, Braks MAH, Schaffner F, Stroo A, Wouters RM, van der Beek JG.   +7 more
europepmc   +1 more source

Human impact on the recent population history of the elusive European wildcat inferred from whole genome data. [PDF]

BMC Genomics, 2022
Nieto-Blázquez ME, Schreiber D, Mueller SA, Koch K, Nowak C, Pfenninger M.   +5 more
europepmc   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Estimating the Distribution of Fitness Effects in Aye-Ayes (Daubentonia madagascariensis), Accounting for Population History as Well as Mutation and Recombination Rate Heterogeneity. [PDF]

Am J Primatol
Soni V, Versoza CJ, Pfeifer SP, Jensen JD.   +3 more
europepmc   +1 more source

Genomic Insights Into the Population History and Biological Adaptation of Southwestern Chinese Hmong-Mien People. [PDF]

Front Genet, 2021
Liu Y, Xie J, Wang M, Liu C, Zhu J, Zou X, Li W, Wang L, Leng C, Xu Q, Yeh HY, Wang CC, Wen X, Liu C, He G.   +14 more
europepmc   +1 more source