Results 211 to 220 of about 14,560,391 (301)

Estimating the Distribution of Fitness Effects in Aye-Ayes (Daubentonia madagascariensis), Accounting for Population History as Well as Mutation and Recombination Rate Heterogeneity. [PDF]

Am J Primatol
Soni V, Versoza CJ, Pfeifer SP, Jensen JD.   +3 more
europepmc   +1 more source

Ancient genomes illuminate Eastern Arabian population history and adaptation against malaria

, 2023
Martiniano R, Haber M, Almarri MA, Mattiangeli V, Kuijpers MCM, Chamel B, Breslin EM, Littleton J, Almahari S, Aloraifi F, Bradley DG, Lombard P, Durbin R.   +12 more
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Cross-continental transmission and host adaptation of <i>Mycobacterium tuberculosis</i> in China unveiled by population history reconstruction and adaptive evolution signal detection. [PDF]

IMetaOmics
Wu W, Liu Z, Chen H, Tang Y, Jiang Z, Zhang Y, Zhang A, Zhou Z, Marks RS, Zhang F, Yuan H, Yu Y, Mao K, Dinnyés A, Rastogi N, Xie J, Sun Q.   +16 more
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Genomic insights into the population history of fat-tailed sheep and identification of two mutations that contribute to fat tail adipogenesis. [PDF]

J Adv Res
Jin M, Liu G, Liu E, Wang L, Jiang Y, Zheng Z, Lu J, Lu Z, Ma Y, Liu Y, Quan K, Jin H, Jiang X, Fei X, Li T, Cao J, Yuan Z, Du L, Wang H, Wei C.   +19 more
europepmc   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

On “Weak” and “Strong” Population Momentum

, 2009
Levin, Simon A., Espenshade, Thomas J., Olgiati, Analia S.   +2 more
core  

Ten years of the The Dietary Guidelines for the Brazilian Population: history, science and policy. [PDF]

Epidemiol Serv Saude
Jaime PC, Braga MBL.
europepmc   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source