Results 171 to 180 of about 7,020,352 (297)

Accelerated Bayesian inference of population size history from recombining sequence data. [PDF]

Nat Genet
Terhorst J.
europepmc   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Population size bottleneck [PDF]

Nature, 1990
openaire   +1 more source

Exceedingly low genetic diversity in snow leopards due to persistently small population size. [PDF]

Proc Natl Acad Sci U S A
Solari KA, Morgan S, Poyarkov AD, Weckworth B, Samelius G, Sharma K, Ostrowski S, Ramakrishnan U, Kubanychbekov Z, Kachel S, Johansson Ö, Lkhagvajav P, Hemmingmoore H, Alexandrov DY, Bayaraa M, Grachev A, Korablev MP, Hernandez-Blanco JA, Munkhtsog B, Rosenbaum B, Rozhnov VV, Madad Rajabi A, Noori H, Suryawanshi KR, Armstrong EE, Petrov DA.   +25 more
europepmc   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Genomic Evidence of Low Contemporary Effective Population Size and Southern Genetic Reservoirs in an Island Endemic Epiphytic Orchid of Taiwan. [PDF]

Ecol Evol
Chen WY, Sun Y, Wu SP, Huang JP.
europepmc   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Variance of <i>K</i> _s distribution corrects the bias in the divergence caused by the ancestral population size. [PDF]

Front Genet
Li MJ, Li XX, Xu LL, Zhang BW.
europepmc   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Measuring changes in <i>Plasmodium falciparum</i> census population size in response to sequential malaria control interventions. [PDF]

Elife
Tiedje KE, Zhan Q, Ruybal-Pésantez S, Tonkin-Hill G, He Q, Tan MH, Argyropoulos DC, Deed S, Ghansah A, Bangre O, Oduro AR, Koram KA, Pascual M, Day KP.   +13 more
europepmc   +1 more source