Results 191 to 200 of about 11,596,072 (260)

On “Weak” and “Strong” Population Momentum

, 2009
Levin, Simon A., Espenshade, Thomas J., Olgiati, Analia S.   +2 more
core  

Accelerated Bayesian inference of population size history from recombining sequence data. [PDF]

Nat Genet
Terhorst J.
europepmc   +1 more source

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Aging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho, Quang Le, Ngoc Thach Tran, Van Viet Ung, Loc Vu   +4 more
wiley   +1 more source

Real-time PCR to estimate population size of typical bacteria associated with the Cecum of Japanese rock ptarmigans. [PDF]

J Vet Med Sci
Tsuchida S, Suzuki-Hashido N, Tsuzuki T, Ushida K.   +3 more
europepmc   +1 more source

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

Aging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi, Emily Herdman, Danielle Westmark, Vijaya R. Bhatt   +3 more
wiley   +1 more source

Exceedingly low genetic diversity in snow leopards due to persistently small population size. [PDF]

Proc Natl Acad Sci U S A
Solari KA, Morgan S, Poyarkov AD, Weckworth B, Samelius G, Sharma K, Ostrowski S, Ramakrishnan U, Kubanychbekov Z, Kachel S, Johansson Ö, Lkhagvajav P, Hemmingmoore H, Alexandrov DY, Bayaraa M, Grachev A, Korablev MP, Hernandez-Blanco JA, Munkhtsog B, Rosenbaum B, Rozhnov VV, Madad Rajabi A, Noori H, Suryawanshi KR, Armstrong EE, Petrov DA.   +25 more
europepmc   +1 more source

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi, Katharine Lee, Kerry C. Nix, Miguel Menchaca, Xiwei Shé, Lorelei Santa Maria, Wei Wu, Zihuai He, Fiona M. Baumer   +8 more
wiley   +1 more source

Controlling for life-history traits in vertebrates reveals that effective population size does not affect mutation rate or genome size. [PDF]

Proc Natl Acad Sci U S A
Weinstein B, Roy SW.
europepmc   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source