Results 141 to 150 of about 13,097,883 (301)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Structured Population Models: Introduction

Theoretical Population Biology, 2012
Tuljapurkar, Shripad, Coulson, Tim, Steiner, Uli   +2 more
openaire   +3 more sources

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Genetical Structure of Populations [PDF]

Nature, 1950
openaire   +4 more sources

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Present and prospective state of policy approaches to fertility [PDF]

, 1975
For more about the East-West Center, see http://www.eastwestcenter.org/A shortened version of a paper originally prepared for a meeting of the Ford Foundation's international population staff held at Cali, Colombia, Oct.
Saunders, Lyle, Simmons, Ozzie G.
core   +1 more source

Unlocking the secret life of blue mussels: Exploring connectivity in the Skagerrak through biophysical modeling and population genomics

Evolutionary Applications
Knowledge of functional dispersal barriers in the marine environment can be used to inform a wide variety of management actions, such as marine spatial planning, restoration efforts, fisheries regulations, and invasive species management.
Malin Gustafsson, Åsa Strand, Ane T. Laugen, Jon Albretsen, Carl André, Göran Broström, Per Erik Jorde, Halvor Knutsen, Olga Ortega‐Martinez, Marte Sodeland, Malin Waern, Anna‐Lisa Wrange, Pierre De Wit   +12 more
doaj   +1 more source

Population Structure of Morpho helenor peleides (Kollar, 1850) (Lepidoptera: Nymphalidae) Under Different Land Uses in the Caribbean Region of Colombia

Insects
Morpho butterflies have the potential to act as a bioindicator species, since they are sensitive to changes in land uses and forest degradation; there have been few population studies of butterflies in the Caribbean region of Colombia.
Carlos Elías Altamar-Bolívar, Juan David González-Trujillo, Luis G. Quijano-Cuervo, María Inés Moreno-Pallares, Neis José Martínez-Hernández   +4 more
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

GENETIC STRUCTURE OF POPULATIONS [PDF]

Evolution, 1975
openaire   +2 more sources