Results 141 to 150 of about 1,867,225 (312)
Population structure and species description of aquatic Sphingomonadaceae [PDF]
, 2012 Prokaryotes consist of the domains of Bacteria and Archaea and exist since approximately 3.8 billion years. Prokaryotes, despite the small size of the individual cells, are regarded to represent the 'unseen majority' among the living world as they occur ...
Chen, Hong
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Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Evolutionary ApplicationsKnowledge of functional dispersal barriers in the marine environment can be used to inform a wide variety of management actions, such as marine spatial planning, restoration efforts, fisheries regulations, and invasive species management.
Malin Gustafsson +12 more
doaj +1 more source
InsectsMorpho butterflies have the potential to act as a bioindicator species, since they are sensitive to changes in land uses and forest degradation; there have been few population studies of butterflies in the Caribbean region of Colombia.
Carlos Elías Altamar-Bolívar +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Social and population structure of striped and Risso's dolphins in the Mediterranean Sea [PDF]
, 2004 The aim of this research was to apply genetic methods to a better understanding of the evolution of population genetic structure in two dolphin species inhabiting a shared geographic range in the Mediterranean Sea and eastern North Atlantic (ENA).
Gaspari, Stefania
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Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Stochastic Models in Population Genetics: Genealogy and Genetic Differentiation in Structured Populations [PDF]
, 1994 PhDThe theory of probability and stochastic processes is applied to a current issue in population genetics, namely that of genealogy and genetic differentiation in subdivided populations.
Herbots, Hilde Maria Jozefa Dominiek
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Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source