Results 131 to 140 of about 1,252 (156)

Porcine Circoviruses: A Review [PDF]

open access: yesJournal of Veterinary Diagnostic Investigation, 2000
Porcine circoviruses (PCV) are small nonenveloped DNA viruses containing a unique single-stranded circular genome. Previously, no recognized link was found between PCV infection of pigs and disease, and PCV was considered a nonpathogenic agent. Over the last 5 years, a “novel” PCV, designated PCV2, has been associated with various disease syndromes in ...
G M Allan, John A Ellis
exaly   +4 more sources

Porcine circoviruses: current status, knowledge gaps and challenges

open access: yesVirus Research, 2020
Circoviruses (CV) include some of the smallest viruses known. They were named after their circularly arranged single-stranded DNA genome with a gene encoding a conserved replicase protein on the sense strand. Circoviruses are widely distributed in mammals, fish, avian species and even insects.
Tanja Opriessnig   +2 more
exaly   +6 more sources

Molecular interactions of porcine circoviruses type 1 and type 2 with its host [PDF]

open access: yesVirus Research, 2012
This review discusses the molecular interaction of proteins encoded by porcine circoviruses type 1 (PCV1) and type 2 (PCV2) with respect to the putative role for disease induction. Besides protein:protein interactions also proteins binding to PCV DNA are covered. Moreover, new approaches are considered which have been generated by genomic and proteomic
Annette Mankertz
exaly   +5 more sources

Comparative immunopathogenesis and biology of recently discovered porcine circoviruses [PDF]

open access: yesTransboundary and Emerging Diseases, 2021
Porcine circoviruses are important pathogens of production swine. Porcine circovirus type 1 (PCV1) is non-pathogenic, and discovered as a contaminant of a porcine kidney cell line, PK-15. The discovery of pathogenic variant, PCV2, occurred in the late 90’s in association with post-weaning multi-systemic wasting disease syndrome (PMWS), which is ...
Agm Rakibuzzaman, Sheela Ramamoorthy
exaly   +3 more sources

Porcine circoviruses

Livestock, 2021
Porcine circoviruses have become an integral part of the pig production landscape. They are an evolving pathogen whose impact spans non-pathogenic to association with some of the most serious and far-reaching pathological conditions of pigs.
John Carr, Mark Howells, William Hersey
exaly   +2 more sources

Porcine circoviruses—Small but powerful

open access: yesVirus Research, 2009
When porcine circovirus type 1 (PCV1) was isolated more than 40 years ago as a non-pathogenic contaminant of a porcine kidney cell line, enthusiasm and curiosity kept within reasonable limits. Virologists became more interested, when a second variant was isolated and termed PCV2, because PCV2 is linked to postweaning multisystemic wasting disease (PMWS)
Tim Finsterbusch, Annette Mankertz
exaly   +3 more sources

Discovery and evolving history of two genetically related but phenotypically different viruses, porcine circoviruses 1 and 2

open access: yesVirus Research, 2012
Porcine circoviruses (PCVs) belong to the genus Circovirus, family Circoviridae. and are the smallest non-enveloped, single stranded, negative sense, circular DNA viruses that replicate autonomously in mammalian cells.
Gordon Allan   +2 more
exaly   +2 more sources

Comparative analysis of the transcriptional patterns of pathogenic and nonpathogenic porcine circoviruses

open access: yesVirology, 2003
The RNAs of porcine circovirus type 1 (PCV1) synthesized in PK15 cells were characterized. A total of 12 RNAs were detected. They include the viral capsid protein RNA (CR), a cluster of eight Rep-associated RNAs (designated Rep, Rep', Rep3a, Rep3b, Rep3c-1, Rep3c-2, Rep3c-3, and Rep3c-4), and three NS-associated RNAs (designated NS462, NS642, and NS0).
Andrew K Cheung
exaly   +3 more sources

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