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Distribution of Porcine Cytomegalovirus in Infected Donor Pigs and in Baboon Recipients of Pig Heart Transplantation

open access: yesViruses, 2018
The porcine cytomegalovirus (PCMV) is a herpesvirus that may pose a risk for xenotransplantation using pig cells, tissues, or organs. Here, three orthotopic pig heart transplantations into baboons were studied.
Uwe Fiebig   +10 more
doaj   +3 more sources

Molecular Detection of Porcine Cytomegalovirus, Porcine Parvovirus, Aujeszky Disease Virus and Porcine Reproductive and Respiratory Syndrome Virus in Wild Boars Hunted in Serbia during 2023 [PDF]

open access: yesVeterinary Sciences
Porcine cytomegalovirus (PCMV) infection is widespread worldwide and has a high prevalence in swine herds, especially in countries with intensive swine production. PCMV is zoonotic and can impact xenotransplants.
Nemanja Jezdimirović   +9 more
doaj   +2 more sources

Role of a Porcine Herpesvirus, PCMV/PRV, in Xenotransplantation. [PDF]

open access: yesTranspl Int
Xenotransplantation using pig organs may be associated with the transmission of porcine viruses that could cause disease in recipients. A well-known example is the porcine cytomegalovirus, which is actually a porcine roseolovirus, hence abbreviated as ...
Denner J.
europepmc   +3 more sources

Virological Characterization of Pigs with Erythema Multiforme [PDF]

open access: yesMicroorganisms, 2022
Erythema multiforme in pigs is an acute, self-limiting disease characterized by red skin areas and often associated with anorexia, fever and respiratory problems. The cause of the disease remains unknown.
Sabrina Halecker   +5 more
doaj   +3 more sources

Comprehensive Protocols for Detecting Xenotransplantation-Relevant Viruses [PDF]

open access: yesMethods and Protocols
Xenotransplantation using pig cells, tissues, or organs is advancing toward clinical application to address the shortage of human donor organs for treating organ failure.
Hina Jhelum   +2 more
doaj   +2 more sources

How Does a Porcine Herpesvirus, PCMV/PRV, Induce a Xenozoonosis. [PDF]

open access: yesInt J Mol Sci
Porcine cytomegalovirus/porcine roseolovirus (PCMV/PRV), a porcine herpesvirus, has been shown to significantly reduce the survival time of porcine xenotransplants in non-human primates.
Denner J.
europepmc   +3 more sources

Commentary: Oral fluid testing can be used to monitor xenotransplant donor herds for porcine cytomegalovirus/roseolovirus status. [PDF]

open access: yesFront Vet Sci
To address the shortage of human tissues and organs for treating organ failure, xenotransplantation is progressing toward clinical application. Pigs have been chosen as donor species for various reasons, and extensive genetic modifications are being ...
Denner J.
europepmc   +3 more sources

Screening for Viruses in Indigenous Greek Black Pigs [PDF]

open access: yesMicroorganisms
The successful advancement of xenotransplantation has led to the development of highly sensitive detection systems for the screening of potentially zoonotic viruses in donor pigs and preventing their transmission to the recipient.
Hina Jhelum   +5 more
doaj   +3 more sources

Porcine Lymphotropic Herpesvirus (PLHV) Was Not Transmitted During Transplantation of Genetically Modified Pig Hearts into Baboons. [PDF]

open access: yesInt J Mol Sci
Porcine lymphotropic herpesviruses -1, -2, and -3 (PLHV-1, PLHV-2, and PLHV-3) are gammaherpesviruses that are widespread in pigs. These viruses are closely related to the human pathogens Epstein–Barr virus (EBV) and Kaposi sarcoma-associated herpesvirus
Jhelum H   +6 more
europepmc   +3 more sources

Mining Porcine Blood Whole-DNA Sequencing Datasets to Uncover Pig Viromes: An Exploratory Application to Identify Potential Infecting Agents of an Undefined Disease Outbreak [PDF]

open access: yesVeterinary Sciences
Pigs are affected by a variety of pathogenic agents that need to be identified correctly and diagnosed even when co-infections may complicate the application of specific and targeted assays.
Samuele Bovo   +6 more
doaj   +2 more sources

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