Results 21 to 30 of about 807 (120)

Application of Methods Detecting Xenotransplantation-Relevant Viruses for Screening German Slaughterhouse Pigs [PDF]

Viruses
Detection methods have been developed to prevent transmission of zoonotic or xenozoonotic porcine viruses after transplantation of pig organs or cells to the recipient (xenotransplantation).
Hina Jhelum, Benedikt Kaufer, Joachim Denner   +2 more
doaj   +2 more sources

Molecular survey of Cytomegalovirus shedding profile in commercial pig herds in Brazil

Journal of Infection in Developing Countries, 2016
Introduction: Porcine cytomegalovirus (PCMV) causes rhinitis in both young and older pigs. The present study describes the detection and characterization of shedding profiles of PCMV in nine farrow-to-finish Brazilian swine herds.
Maurício Cabral Dutra, Luisa Zanolli Moreno, Cristina Roman Amigo, Maria Roberta Felizardo, Thais Sebastiana Porfida Ferreira, Tania Alen Coutinho, Alexandre Abelardo Sanches, Jason Ardila Galvis, Marina Moreno, Andrea Micke Moreno   +9 more
doaj   +3 more sources

Porcine Lymphotropic Herpesviruses (PLHVs) and Xenotranplantation [PDF]

Viruses, 2021
Porcine lymphotropic herpesviruses -1, -2 and -3 (PLHV-1, PLHV-2 and PLHV-3) are gammaherpesviruses which are widespread in pigs. They are closely related to the Epstein–Barr virus (EBV) and Kaposi sarcoma herpesvirus, both of which cause severe diseases
Joachim Denner
doaj   +2 more sources

Mining Porcine Blood Whole-DNA Sequencing Datasets to Uncover Pig Viromes: An Exploratory Application to Identify Potential Infecting Agents of an Undefined Disease Outbreak [PDF]

Veterinary Sciences
Pigs are affected by a variety of pathogenic agents that need to be identified correctly and diagnosed even when co-infections may complicate the application of specific and targeted assays.
Samuele Bovo, Anisa Ribani, Giuseppina Schiavo, Valeria Taurisano, Matteo Bolner, Francesca Bertolini, Luca Fontanesi   +6 more
doaj   +2 more sources

Pig-to-human kidney xenotransplants using genetically modified minipigs [PDF]

Cell Reports Medicine
Summary: This study develops an observational model to assess kidney function recovery and xenogeneic immune responses in kidney xenotransplants, focusing on gene editing and immunosuppression.
Yi Wang, Gang Chen, Dengke Pan, Hui Guo, Hongtao Jiang, Jianli Wang, Hao Feng, Songzhe He, Jiaxiang Du, Man Zhang, Tao Li, Yong Wang, Hang Yu, Huiling Gan, Quan Wen, Zhian Song, Desheng Li, Yifan Yu, Huanliang Wang, Bing Li, Yong You, Shen Zhou, Mingfa Wang, Lili Liu, Liang Xu, Meng Yang, Hua Pei, Kang Zhang, Zhonghua K. Chen   +28 more
doaj   +2 more sources

Potential Infectious Complications in Pig Xenograft Donors and Recipients [PDF]

Transplant International
Preclinical and clinical xenotransplantation trials have shown that successful outcomes depend on a number of factors including the prevention of xenozoonoses.
Nicolas J. Mueller, Linda Scobie
doaj   +2 more sources

Is There an Ethical Dilemma in Xenotransplantation? [PDF]

Xenotransplantation
ABSTRACT As clinical trials in xenotransplantation commence, the question of whether participants may withdraw from research is being intensely debated. Some authors argue that xenotransplant recipients should be subject to lifelong monitoring because of the potential risk of zoonotic or xenozoonotic infections affecting third parties.
Denner J.
europepmc   +2 more sources

The First Clinical Renal Xenotransplantation Study (EXPAND): Evaluating Safety, Function, and Zoonotic Risks. [PDF]

Health Care Sci
Health Care Science, Volume 4, Issue 6, Page 377-380, December 2025.
Nashan B.
europepmc   +2 more sources

Role of a Porcine Herpesvirus, PCMV/PRV, in Xenotransplantation. [PDF]

Transpl Int
Xenotransplantation using pig organs may be associated with the transmission of porcine viruses that could cause disease in recipients. A well-known example is the porcine cytomegalovirus, which is actually a porcine roseolovirus, hence abbreviated as ...
Denner J.
europepmc   +2 more sources

OMICS Analyses in Xenotransplantation: Initial Findings, Key Precautions, and Virus Infections. [PDF]

Xenotransplantation
ABSTRACT OMICS analyses have the potential to greatly enhance our understanding of rejection and other processes in xenotransplantation. These approaches may therefore contribute to extending the survival time of xenotransplants. Initial OMICS studies in brain‐dead patients following transplantation of pig kidneys or hearts revealed increased ...
Denner J.
europepmc   +2 more sources