Presence of porcine cytomegalovirus, a porcine roseolovirus, in wild boars in Italy and Germany [PDF]
, 2023 Porcine cytomegalovirus (PCMV), a porcine roseolovirus (PRV) that is closely related to human herpesviruses 6 and 7, is commonly found in commercial pigs.
Denner, Joachim +6 more
core +1 more source
Pre-transplant antibody screening and anti-CD154 costimulation blockade promote long-term xenograft survival in a pig-to-primate kidney transplant model [PDF]
, 2015 Xenotransplantation has the potential to alleviate the organ shortage that prevents many patients with end-stage renal disease from enjoying the benefits of kidney transplantation.
Adams, Andrew B +12 more
core +1 more source
Neoplastic transformation of porcine mammary epithelial cells in vitro and tumor formation in vivo. [PDF]
, 2015 BackgroundThe mammary glands of pigs share many functional and morphological similarities with the breasts of humans, raising the potential of their utility for research into the mechanisms underlying normal mammary function and breast carcinogenesis ...
Borowsky, AD +5 more
core +4 more sources
Xenotransplantation Literature Update: January-June 2025. [PDF]
XenotransplantationABSTRACT From January to June 2025, the field of xenotransplantation progressed rapidly toward clinical translation, with landmark compassionate‐use cases, peer‐reviewed reports of porcine kidney, heart, and liver transplants in humans, and the release of authoritative international guidelines.
Shirini K, Ladowski JM, Meier RPH.
europepmc +2 more sources
Investigating porcine parvoviruses genogroup 2 infection using in situ polymerase chain reaction [PDF]
, 2018 Background Porcine parvovirus 2 (PPV2) was detected in swine serum without showing any relationship with disease. The emergence of the virus seemed to be a unique event until other genetically highly similar parvoviruses were identified in China and ...
A Csagola +49 more
core +1 more source
Reduction of the survival time of pig xenotransplants by porcine cytomegalovirus
Virology Journal, 2018 Background Xenotransplantation using pig cells, tissues and organs may help to overcome the shortage of human tissues and organs for the treatment of tissue and organ failure.
Joachim Denner
doaj +1 more source
Safety of Xenotransplantation: Development of screening methods and testing for porcine viruses [PDF]
, 2018 Xenotransplantation using pig cells, tissues or organs might be a promising solution to overcome the shortage for organs suitable for allotransplantation. Because of several reasons, the pig is currently the favoured donor species.
Janich geb. Plotzki, Elena
core +1 more source
The Pseudorabies Virus DNA Polymerase Accessory Subunit UL42 Directs Nuclear Transport of the Holoenzyme [PDF]
, 2016 Pseudorabies virus (PRV) DNA replication occurs in the nuclei of infected cells and requires the viral DNA polymerase. The PRV DNA polymerase comprises a catalytic subunit, UL30, and an accessory subunit, UL42, that confers processivity to the enzyme ...
Chang-Ming Liu +6 more
core +2 more sources
, 2022 Abstract Porcine cytomegalovirus (PCMV), which is a porcine roseolovirus (PRV), closely related to the human herpesviruses 6 and 7, is common among commercial pigs. PCMV/PRV was shown to be important in xenotransplantation because transmission of PCMV/PRV in preclinical trials transplanting pig organs into non-human primates was associated with
Sabrina Hansen +6 more
openaire +1 more source
Molecular survey of Cytomegalovirus shedding profile in commercial pig herds in Brazil
Journal of Infection in Developing Countries, 2016 Introduction: Porcine cytomegalovirus (PCMV) causes rhinitis in both young and older pigs. The present study describes the detection and characterization of shedding profiles of PCMV in nine farrow-to-finish Brazilian swine herds.
Maurício Cabral Dutra +9 more
doaj +1 more source