Results 61 to 70 of about 1,425 (131)
Xenoperfusion—The Transformative Role of Machine Perfusion in Xenotransplantation
Xenotransplantation, Volume 33, Issue 3, May/June 2026.ABSTRACT Recent advances in xenotransplantation have gained substantial public and clinical attention as genetically modified porcine organs are now being transplanted into living human recipients. While only case reports have been published to date, the first clinical trials for kidney xenotransplantation are now ongoing.
Florian Huwyler +3 more
wiley +1 more source
Is There an Ethical Dilemma in Xenotransplantation?
Xenotransplantation, Volume 33, Issue 3, May/June 2026.ABSTRACT As clinical trials in xenotransplantation commence, the question of whether participants may withdraw from research is being intensely debated. Some authors argue that xenotransplant recipients should be subject to lifelong monitoring because of the potential risk of zoonotic or xenozoonotic infections affecting third parties.
Joachim Denner
wiley +1 more source
Mutations in a Highly Conserved Motif of nsp1? Protein Attenuate the Innate Immune Suppression Function of Porcine Reproductive and Respiratory Syndrome Virus [PDF]
, 2016 Citation: Li Y, Shyu D-L, Shang P, Bai J, Ouyang K, Dhakal S, Hiremath J, Binjawadagi B, Renukaradhya GJ, Fang Y. 2016. Mutations in a highly conserved motif of nsp1?
Bai, Jianfa +9 more
core +1 more source
Cell Biology International, Volume 50, Issue 2, February 2026.ABSTRACT Advancing reproductive technologies in livestock is essential to improve both productivity and genetic potential of cattle. Despite this importance, application of reproductive biotechnologies in cattle breeding remains limited. Bovine granulosa cells (bGCs), which are key components of the ovarian follicle, are critical in female reproduction
Lanlan Bai +12 more
wiley +1 more source
First virological and pathological study of Go¨ttingen Minipigs with Dippity Pig Syndrome (DPS) [PDF]
, 2023 Dippity Pig Syndrome (DPS) is a well-known but rare complex of clinical signs affecting minipigs, which has not been thoroughly investigated yet. Clinically affected animals show acute appearance of red, exudating lesions across the spine.
Denner, Joachim +13 more
core +1 more source
eVLP‐Mediated Cas9 Delivery for Preventing IBMIR in Islet Transplantation
Small, Volume 22, Issue 1, 2 January 2026.Engineered virus‐like particles (eVLPs) are used to deliver Cas9 nuclease to knock out tissue factor (TF) and plasminogen activator inhibitor‐1 (PAI‐1) genes in pancreatic islets. The edited islets maintained viability and function, while reducing instant blood‐mediated inflammatory reaction (IBMIR) markers and improving glycemic control in diabetic ...
Manju Shrestha +6 more
wiley +1 more source
Viruses, 2019 Xenotransplantation using pig tissues and organs is under development in order to alleviate the increasing shortage of human transplants. Since xenotransplantation may be associated with the transmission of porcine microorganisms to the human recipient ...
Luise Krüger +6 more
doaj +1 more source
Comparative analysis of Roseoloviruses in humans, pigs, mice, and other species [PDF]
, 2019 Viruses of the ...
Bigley, Tarin M +5 more
core +2 more sources
Microchimerism, PERV and Xenotransplantation [PDF]
, 2023 Microchimerism is the presence of cells in an individual that have originated from a genetically distinct individual. The most common form of microchimerism is fetomaternal microchimerism, i.e., cells from a fetus pass through the placenta and establish ...
Denner, Joachim
core +1 more source
Acta Physiologica, Volume 241, Issue 9, September 2025.ABSTRACT Aim The aim of this study is to determine the possible role of N‐methyl‐D‐aspartate receptor (NMDAR) dysregulation in the ischemic electrical remodeling observed in patients with myocardial infarction (MI) and elucidate the underlying mechanisms.
Yuxian He +7 more
wiley +1 more source